Preliminary program

  Monday 26 Tuesday 27 Wednesday 28 Thursday 29 Friday 30
8:30  
9:00

Session I: VIRUS-HOST INTERACTIONS - 1.
Chair: Howard Lipton.
Keynote lecture. Frank Van Kuppeveld: Membrane rearrangements in enterovirus infected cells.

I1. George Belov: Poliovirus replication depends on a cellular membrane traffic protein GBF1.
I2. Elisabetta Groppelli: Aphthovirus cell entry: identification of the ERAV endocytic pathway and insight into the mechanism of genome release.
I3. William Jackson: Inhibition of autophagic cell death: a novel effect of picornavirus infection.
I4. Satoshi Koike: Studies on poliovirus RNA sensors.
9:15
9:30
9:45
10:00
10:15
10:30 Coffee break
10:45  
11:00

Session J: VIRUS-HOST INTERACTIONS - 2.
Chair: Timo Hyypiä.
Keynote lecture. Raul Andino: Picornaviruses dancing with the RNAi machinery.

J1. Elizabeth Rieder: Host cell factors involved in the life cycle of FMDV.
J2. Teresa de los Santos: A conserved domain in the leader proteinase of foot-and-mouth disease virus is required for proper subcellular localization and function.
J3. Stanley M. Lemon: Subversion and control of HAV infections by innate antiviral defenses.
J4. Noemí Sevilla: Foot-and-mouth disease virus (FMDV)-dendritic cells (DC) interaction: role of IL-10 in early immunosuppression during FMDV infection in swine.
11:15
11:30
11:45
12:00
12:15
12:30  
12:45 Lunch
13:00
13:15
13:30
13:45  
14:00 Session K: VIRUS-HOST INTERACTIONS-3.
Chair: Raymond Roos.
Keynote lecture. Florence Colbère-Garapin: Persistent poliovirus infection: a matter of life and death.

K1. Antonio Toniolo: Detection of persistent polioviruses in patients with the post-polio syndrom.
K2. Nadine Jarasch: Experimental coxsackievirus B3 infection of primary murine and human CD19+ B lymphocytes: mode of action.
K3. Karin Klingel: The evolvement of chronic CVB3-myocarditis is driven by disturbances in the expansion of cross-presenting CD4-/CD8+ dendritic cells and chemokine secretion by dendritic cells.
K4. William Golde: Suppression of swine natural killer cell (NK) function during acute infection with foot-and-mouth disease virus (FMDV).
K5. Nicholas Juleff: Foot-and-mouth disease virus induces a specific and rapid CD4+ T cell-independent neutralizing antibody response in naïve cattle.
14:15
14:30
14:45
15:00
15:15
15:30 Coffee break
15:45
16:00 Hot topic session L. Vadim I. Agol: How and why do picornaviruses harm their host cells?

L1. Vadim. I. Agol: Introductory remarks.
L2. Paul Monaghan: Host membrane alterations in response to picornavirus infection.
L3. Arnaud Autret: Early phosphatidylinositol 3-Kinase/AKT pathway activation limits poliovirus-induced JNK-mediated cell death.
L4. Howard Lipton: BH3 only proapoptotic members and the upstreTam signaling events involved in Theiler’s virus-induced intrinsic apoptosis in M1-D macrophages.
L5. Barbara M. Schulte: Phagocytosis of picornavirus-infected cells induces an RNA-dependent antiviral state in human dendritic cells.
Open discussion.
16:15
16:30
16:45
17:00
17:15
17:30
17:45
18:00  
18:15
18:30 Dinner
18:45
19:00
19:15
19:30
19:45
20:00
20:15
20:30 Poster viewing
20:45
21:00
21:15
21:30
21:45
22:00  
22:15  
22:30