Our main goals are to decipher the genetic determinants of bacterial plant diseases and to characterize the main executioners of the hypersensitive response cell death. We combine genetics, biochemistry and molecular biology in an integrated approach to study both plants and their pathogens. The Bacterial Plant Disease and Cell Death team is located in the Centre for Research in Agricultural Genomics (CRAG) in Bellaterra, Barcelona. The CRAG is a consortium between the Spanish National Research Council (CSIC), the Catalan Institute for Food and Agricultural Research and Technology (IRTA), the University of Barcelona (UB) and the Autonomous University of Barcelona (UAB).
Genetic determinants of Disease
Bacterial wilt caused by the wide-host range pathogen Ralstonia solanacearum is a devastating disease affecting over 200 plant species from disparate families including potato, tomato, peanut, eucalyptus, clove, etc. We study the expression and the functions of R. solanacearum virulence genes inside its plant hosts.Read more
Metacaspases as executioners of programmed cell death
Programmed cell death (PCD) is an essential process for normal development and defense against pathogens in all multicellular organisms.