Former Positions
Present Research Interest
Group Members
Recent Publications
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Email: Pmarrero@samba.cnb.uam.es
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Former Positions:

Present Research Interest:

Current Group Members:

1.- Maria Jose Barrero Fellowship from Catalonian Government  second year student
Thesis tittle: Role of postranscriptional mechanism on mitochondrial HMG-CoA synthase gene expression.

2.- Carine Nicot       Fellowship from Trend Mobility Research Program first year student
Thesis tittle: Transcriptional and allosteric regulation of liver carnitine palmitoyl transferase I (L-CPT I) in a non ketogenic mammals

European Master in Biotechnology (The Nottingham Trent University)
Master title: Characterization of a peroxisome proliferator-responsive element (PPRE) located upstream of the pig mitochondrial HMG-CoA synthase gene. Attempts to isolate a cDNA encoding for the porcine liver carnitine palmytoil transferase I 1997

3.- Nuria Camarero   Fellowship from Spanish Government   first year student
Thesis tittle: Role of mitochondrial HMG-CoA synthase expression in extra-hepatic tissues

Former group Members:

1.- Sean Harrison Adams, Ph.D.       1994-1995
2.- Joana Cabaño Juanola                 1993-1994

Master title: E. coli expression of HMG-CoA synthase 1 and 2 from Blattella germanica. Kinetic characterization of HMG-CoA synthase 1.

3.- Judith Mallolas Jimenez                1995-1996

Master title: Isolation and characterization of HMG-CoA synthase promoter from pig.

4.-    Clarice S. Alho  Fellow from Brazilian Government   last year student
Thesis title: Gene expression of mitochondrial 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase, liver carnitine palmitoyltransferase I (L-CPT I), and phosphoenolpyruvate carboxikinase (PEPCK) in a poorly ketogenic Mammal: effect of starvation during neonatal period of the piglet.

Recent Publications:

Mascaro-C; Acosta-E; Ortiz-JA; Marrero-PF; Hegardt-FG; Haro-D.

Control of human muscle type carnitine palmitoyltransferase I gene transcription by peroxisome proliferator-activated receptor. J-Biol-Chem. 1998; 273

Cabano-J; Buesa-C; Hegardt-FG; Marrero-PF.

Catalytic properties of recombinant 3-hydroxy-3-methylglutaryl coenzyme A synthase-1 from Blattella germanica. Insect-Biochem-Mol-Biol. 1997; 27: 499-505

Adams-SH; Alho-CS; Asins-G; Hegardt-FG; Marrero-PF.

Gene expression of mitochondrial 3-hydroxy-3-methylglutaryl-CoA synthase in a poorly ketogenic mammal: effect of starvation during the neonatal period of the piglet. Biochem-J. 1997; 324: 65-73

Casals-N; Buesa-C; Piulachs-MD; Cabano-J; Marrero-PF; Belles-X; Hegardt-FG.

Coordinated expression and activity of 3-hydroxy-3-methylglutaryl coenzyme A synthase and reductase in the fat body of Blattella germanica (L.) during vitellogenesis. Insect-Biochem-Mol-Biol. 1996; 26: 837-43

Marrero-PF; Poulter-CD; Edwards-PA.

Effects of site-directed mutagenesis of the highly conserved aspartate residues in domain II of farnesyl diphosphate synthase activity. J-Biol-Chem. 1992; 267: 21873-8

Ayte-J; Gil-Gomez-G; Haro-D; Marrero-PF; Hegardt-FG.

Rat mitochondrial and cytosolic 3-hydroxy-3-methylglutaryl-coa synthases are encoded by two different genes. Proceedings of the National Academy of Sciences. 1990; 87: 3874-3878