@article {179,
	title = {Conjugate additions to phenylglycinol-derived unsaturated delta-lactams. Enantioselective synthesis of uleine alkaloids},
	journal = {The Journal of organic chemistry},
	volume = {69},
	year = {2004},
	month = {2004/12/10/},
	pages = {8681 - 8693},
	abstract = {The stereochemical outcome of the conjugate addition of a variety of stabilized nucleophiles (2-indoleacetic enolates and sulfur-stabilized anions) to the phenylglycinol-derived unsaturated lactams trans-2, cis-2, and its 8-ethyl-substituted analogue 10 is studied. The factors governing the exo or endo facial stereoselectivity are discussed. This methodology provides short synthetic routes to either cis- or trans-3,4-disubstituted enantiopure piperidines as well as efficient routes for the enantioselective construction of the tetracyclic ring system of uleine alkaloids, both in the normal and 20-epi series. The formal total synthesis of several alkaloids of this group is reported.},
	keywords = {Alkaloids/chemical synthesis; Bridged Compounds/chemical synthesis; Crystallography, X-Ray; Glycine/analogs \& derivatives/chemistry; Lactams/chemical synthesis; Molecular Conformation; Stereoisomerism},
	author = {Amat,M. and Perez,M. and Llor,N. and Escolano,C. and F. J. Luque and Molins,E. and Bosch,J.}
}
