@article {184,
	title = {Virtual screening in structure-based drug discovery},
	journal = {Mini reviews in medicinal chemistry},
	volume = {4},
	year = {2004},
	month = {2004/09//},
	pages = {779 - 791},
	abstract = {Recent advances in structure determination and computational methods have encouraged the development of structure-based virtual screening. Here we survey progress in the field and review the most recent methods, validation experiments and real applications, including an in-house example of hit identification for the oncology target Hsp90. These results provide a basis for discussing the current state of structure-based virtual screening and to outline the developments that are expected to have a major impact in the near future.},
	keywords = {Chemical; Models, Combinatorial Chemistry Techniques/methods; Computational Biology/methods; Databases, Factual; Drug Design; Models, Molecular; Structure-Activity Relationship},
	author = {Barril, Xavier and Hubbard,R. E. and Morley,S. D.}
}
