ChemBio Lab

    Chemistry Platform for the Development of New Drugs
 
     
 

Marc Vendrell Escobar, Ramón Subiros Funosas, Lorena  Mendive Tapia, Fernando  Albericio Palomera, Rodolfo Lavilla Grifols,  Rodolfo; Nick D. Read, Nick D. "Fluorogenic compounds, process of preparation thereof and methods of use". PCT Int. Appl. (2016), WO 2016207626.

Luis J, Cruz-Ricondo, Carmen Gutierrez-Reyes, Gerardo A. Acosta-Crespo, Fernando Albericio. "Mixture of multifunctional peptides or polypeptides or combinations thereof that are capable of forming a 2d or 3d matrix for care of the skin, mucosae, scalp and/or hair, and the use thereof in cosmetic or dermopharmaceutical compositions". PCT Int. Appl. (2012), WO 2012168519 A1 20121213.

Joan Gil Santano, Rodolfo Lavilla Grifols, Fernando Albericio Palomera, Alba Pérez Perarnau, Sara Preciado Gallego, Diana Mª González Girones, Daniel Iglesias Serret, Rosario Ramon Albalate. "Fluorinated thiazoles for use in treating cancer". PCT Int. Appl. (2012), WO 2012028757 A1 20120308.

Fernando Albericio, Michele Cristau, Matthieu Giraud, Miriam Góngora Benítez, Judit Tulla-Puche. "Diketopiperazine forming dipeptidyl linker". PCT Int. Appl. (2012), WO 2012055509 A1 20120503.

Francesc Mitjans Prat, Jaume Adan Plana, Carme Calvis Calpe, Fernando Albericio Palomera, Rodolfo Lavilla Grifols, Javier Ruiz Rodríguez. "Cyclic rgd peptides of amino acids based on thiazoles or oxazoles as selective antagonists of the alfa agb 3 integrin". PCT Int. Appl. (2012), WO 2012062777 A1 20120518.

Rubí Zamudio, Judit Tulla-Puche, Fernando Albericio. "Compuestos peptídicos anticancerígenos". Spain # P201231102, July 2012.

Ramon Mangues, Isolda Casanovas, Fernando Albericio, Mercedes Álvarez, Svetlana Savina. "Antitumor 1,2-diphenylpyrrole compounds and their preparation process". PCT Int. Appl. (2011), WO 2011012660 A1 20110203 AN 2011:145322.

 
 
 
 
 
 

 

Sara Preciado Gallego, Alba Pérez Perarnau, Joan Gil Santano, Fernando Albericio Palomera, Rodolfo Lavilla Grifols. "Fluorinated Indolenines for Use in the Treatment of Cancer". PCT Int. Appl. (2013), WO 2013079754 A1 20130606

Leonor Ventosa Rull, Jaume Veciana Miró, Ingrid Cabrera Puig, Elisa Elizondo Saez de Vicuña, Marta Melgarejo Diaz, Miriam Royo Expósito, Fernando Albericio Palomera, Daniel Pulido Martínez, Sanatiago Sala Verges, Jose Luis Corchero Nieto, Simon Schwartz Navarro, Ibane Abasolo Olaortua, Antonio Pedro Villaverde Corrales. "Functionalized Liposomes Useful for the Delievery of Bioactive Compounds". PCT/EP2013/063646, 28 June, 2013.

Marie-Helene Brichard, Jeanne-Marie Cauvin, Christine Devijver, Anne-Sophie Droz, Pascal Gilles, Matthieu Giraud, Daniel Latassa, El Djouhar Rekai, Stephane Varray, Fernando Albericio, Marta Paradis Bas. "Process for the production of exenatide and of an exenatide analogue". PCT Int. Appl. (2011), WO 2011006644 A2 20110120 AN 2011:73485.

Yoav Luxembourg, Fernando Albericio, Yong Zhu. "Method for preparing amino acid with amino protected by alkoxy carbonyl". Faming Zhuanli Shenqing (2010), CAN 153:334373 AN 2010:1028518.

Rodolfo Lavilla Grifols, Joan Gil Santano, Fernando Albericio Palomera, Miriam Miguel Sala, Diana Mª González Gironès, Anna Alcalde López. "Bisthiazole compounds that can be used to treat cancer". PCT Int. Appl. (2010), WO 2010100297.

Ayman El-Faham, Ramon Subirós-Funosas, Fernando Albericio, Yoav Luxembourg, and Sharon Rahamim. "Coupling Agents for the Synthesis of Polypeptides and Polynucleotide". December 2009.

Nancy B. Iannucci, O. Cascone, Silvia A. Camperi, M. Victoria Miranda, Fernando Albericio. "Un método para extraer y purificar un proteína de cáscaras de semilla de soja (glycine max)". Argentina, P-090101603.

M. Camila Martínez Cerron, Mariela M. Marani, Silvia A. Camperi, Osvaldo Cascone, Marina Etcheverrigaray, Fernando Albericio. "Un procedimiento para la extracción y/o purificación de eritropoyetina y ligandos peptídicos utilizables en dicho procedimiento". Argentina, Exp 20090104014.

Fernando Albericio, Ayman El-Faham, Yoav Luxembourg, Ariel Ewenson, Ariel. "Preparation of proton acceptor iminium/carbocation-type and tris(amino)phosphonium-type coupling agents for the synthesis of polypeptides and polynucleotides". PCT Int. Appl. (2009), WO 2009138985.

Leticia Hosta, Mateu Pla, Luis Javier Cruz, Marcelo Kogan, Fernando Albericio. "Antitumor colloidal metal nanoparticles conjugated with Kahalalide F or an analog. ". PCT Int. Appl. (2009), WO 2009095480 A1 20090806 AN 2009:942303.

Rodolfo Lavilla Grifols, Joan Gil Santano, Fernando Albericio Palomera, Miriam Miguel Sala, Diana Mª González Gironès, Anna Alcalde López. "Compuestos bistiazólicos útiles para el tratamiento del cáncer". March 3, 2009. ES 200900659.

Juan Aymami Bofarull, Fernando Albericio Palomera, Anna María Avino Andrés, Josep Farrera Sinfreu, Miriam Royo Exposito, Isabel Navarro Muñoz, Ramon Eritja Casadella. "Polymers and their use as fluorescent labels.". Eur. Pat. Appl. (2009), EP 2014698 A1 20090114 AN 2009:45498.

Juan Aymami Bofarull, Fernando Albericio Palomera, Anna María Avino Andrés, Josep Farrera Sinfreu, Miriam Royo Exposito, Isabel Navarro Muñoz, Ramon Eritja Casadella. "New polymers and their use as fluorescent labels". PCT Int. Appl. (2009), WO 2009007397 A1 20090115 AN 2009:54103.

Andreas Brunner, Oleg Werbitzky, Stephane Varray, Francesca Quattrini, Holger Hermann, Andrew Strong, Fernando Albericio, Judit Tulla-Puche, Yésica García Ramos. "Process for the production of pramlintide". PCT Int. Appl. (2009), WO 2009003666 A1 20090108 AN 2009:24722.

Matthieu Giraud, Fernando Albericio, Albert Isidro-Llobet, Mercedes Álvarez. "Indolesulfonyl protecting groups for protection of guanidine and amino groups". PCT Int. Appl. (2009) WO 2009135645.

Judit Tulla-Puche, Eleonora Marcucci, Núria Bayó-Puxan, Fernando Albericio, Carmen Cuevas. "Antitumoral compounds". PCT Int. Appl. (2009), WO 2009077401 A1 20090625 AN 2009:768146.

Fernando Albericio, Ayman El-Faham, Yoav Luxembourg, Ariel Ewenson. "Proton Acceptor Immonium-type Coupling Reagents". PCT Int. Appl. (2008), WO 2008139481.

Matthieu Giraud, Fernando Albericio, Francesca Quattrini, Oleg Werbitzky, Katja Senn, Michaela Williner. "Method for peptide synthesis.". PCT Int. Appl. (2008), WO 2008040536 A1 20080410 CAN 148:379970 AN 2008:445114.

Judit Tulla-Puche, Nuria Bayó-Puxan, Fernando Albericio. "Method for obtaining bicyclic peptides". PCT Int. Appl. (2008), WO 2008040833 A1 20080410 CAN 148:449920 AN 2008:445253.

Francesc Yraola Font, Silvia García Vicente, Juan Fernández-Recio, Fernando Albericio, Antonio Zorzano, Miriam Royo Exposito, Luc Marti Clauzel, Luc. "Meta-xylylenediamine vanadate salts". PCT Int. Appl. (2007), WO 2007131996 A1 20071122 CAN 147:534686 AN 2007:1332917.

Royo Exposito, Miriam; Marti Clauzel, Luc; Abella Martin, Anna; Garcia Vicente, Silvia; Testar Yinbert, Xavier; Zorzano Olarte, Antonio; Palacin Prieto, Manuel; Albericio Palomera, Fernando; Yraola Font, Francesc; Mian, Alec. "Arylalkylamine vanadium (v) salts for the treatment and/or prevention of diabetes mellitus". U.S. Pat. Appl. Publ. (2007), US 2007066682 A1 20070322 CAN 146:309354 AN 2007:333004 CAPLUS

Reyes Benitez, Jose Fernando; Francesch Solloso, Andres; Cuevas Marchante, Carmen; Altuna Urquijo, Marta; Pla Queral, Daniel; Alvarez Domingo, Mercedes; Albericio Palomera, Fernando. "Indole derivatives as antitumor compounds". PCT Int. Appl.(2007), WO 2007054748 A1 20070518 CAN 146:528181 AN 2007:538679.

Albericio, Fernando; Cruz, Luis Javier; Garcia, Ramos Yesica; Tulla-Puche, Judit. "Method of peptide synthesis, particularly of Thymosin a1, via side chain-anchoring to a solid phase". PCT Int. Appl. (2006), 33pp. CODEN: PIXXD2 WO 2006117227 A2.

Albericio, Fernando; Cruz, Luis Javier; Garcia-Martin, Fayna; Tulla-Puche, Judit. "Peptide synthesis of a-helixes on PEG resin". PCT Int. Appl. (2006), 18pp. CODEN: PIXXD2 WO 2006108594 A1.

Fernando Albericio; Antonio Zorzano; Luc Marti; Miriam Royo; Francesc Yraola. "Compositions of semicarbazide-sensitive amine oxidase (SSAO) substrates and metal compounds of the VIa and VIb groups of the periodic table for the treatment of diabetes and obesity" Genmedica Therapeutics, Spain. PCT Int. Appl. (2006), 34 pp. CODEN: PIXXD2 WO 2006061140 A2 20060615.

Rubén Ventura, Vicent Casadó, Lluis Biset, Rafael Franco, Fernando Albericio, M. Royo. "Compuestos para el tratamiento de la enfermedad de Parkinson” ES200502546, Universitat de Barcelona, filled October 2005.

Fernando Albericio, Judit Tulla-Puche, Luis J. Cruz, Fayna García-Martín. "T20/Trimeris". EECC 05007694.2. Lonza AG, filled may 2005.

Fernando Albericio, Judit Tulla-Puche, Luis J. Cruz, Yésica García. "Method of peptide synthesis". EECC 05009758.3. Lonza AG, filled may 2005.

Antonio Zorzano, Luc Marti, Fernando Albericio, Miriam Royo, Francesc Yraola. “Composition of SSAO substrates and metal compounds of the 6th main or subgroup of the periodic table”, E.E.CC 04029195.7, Genmedica, E.E.CC., filled December 2004.

Alec Mian, Antonio Zorzano, Luc Marti, Miriam Royo, Fernando Albericio, Francesc Yraola. “Amines, combination of amines and vanadium and amine vanadium salts for the treatment or prevention of dyslipidemia”. Genmedica, USA , filled December 2004.

Antonio Zorzano, Luc Martí, Sívia García, Fernando Albericio, Miriam Royo, Francesc Yraola. “Compounds for inhibiting copper-containing amine oxidases and uses thereof”. Genmedica, US60/598010, filled October, 2004.

Antonio Zorzano, Luc Martí, Anna Abella, Sílvia García, Fernando Albericio, Miriam Royo, Francesc Yraola. “Arylalkylamine vanadium (V) salts for the treatment of Diabetes mellitus”, Genmedica, US2004/0224031A1, filled July, 2004.

Fernando Albericio, Luis J. Cruz, Carmen Cuevas, Andres Francesch, Ernest Giralt. “New Antitumoral Compounds”, U.K. filled February, 2004.

David G. Tubby, Andrés Francesch, Ángel López, Carmen Cuevas, Fernando Albericio, Gerardo Acosta, Luis J. Cruz, Ernest Giralt, Carolina Gracia, Albert Isidro. “Convergent síntesis of kahalalide compounds” PCT Int. Appl. (2005) WO 2005103072, GB 2004-8958 20040422. AN 2005:1170451 Pharma Mar, S.A. USA, E.E.CC.

Fernando Albericio, Ariadna Fernández, Ernest Giralt, Carolina Gracia, Pilar López, Sonia Varon, Carmen Cuevas, Ángel López, Andrés Francesch, José C. Jiménez, Míriam Royo. “Preparation of kahalalide F analogs as antitumor agents”. PCT Int. Appl. (2005) WO2005023846, A1 20050317 CAN 142:298335, AN 2005:239012 Pharma Mar, S.A. USA, E.E.CC.

Carolina García, Antonio Ferrer-Montiel, Montserrat del Fresno, Míriam Royo, Fernando Albericio, Cristina Carreño. “Preparation of guanidylated hydantoins with are capable of blocking the response to chemical substances or thermal stimuli or mediators of inflammation of nocireceptors, and their pharmaceuticals compositions”. PCT (2003) ES 2190884, CAN 142: 114457, Diverdrugs S.L., USA, E.E.CC.

Mercedes Álvarez, Fernando Albericio, Pablo Cironi, Carmen Cuevas, Andrés Francesch, Marta Marfil. "Solid-Phase Synthesis of Lamellarins via cyclocondensation of isoquinolines with haloacetoxyphenylethynylbenzenes". PCT Int. Appl. (2003), WO2004073598, Pharma Mar S.A., EE.CC.

Mercedes Álvarez, Fernando Albericio, Pablo Cironi, Carmen Cuevas, Andrés Francesch, Marta Marfil. "Solid Phase Synthesis of Antitumoral Compounds" (2003), WO 2004073.

Fernando Albericio, Jose M. Caba, Ernest Giralt, Ignacio Manzanares, Ignacio Rodriguez. "Process for producing Trunkamide A Compounds". PCT Int. Appl. (2002), WO2002081506, CAN 137: 295257. Pharma Mar S.A. EE.CC.

Miriam Royo, Guillermo Gerona, Carolina García, L. García, Cristina Carreño, Fernando Albericio, Rosario González-Muñiz, Antonio Ferrer-Montiel. "Compuestos capaces de bloquear la respuesta a sustancias químicas o estímulos térmicos o mediadores de la inflamación de los nociceptores, un método para su obtención y composiciones que los contienen". PCT (2002) ES200202869, Diver Drugs S.L. España.

Mercedes Álvarez, Davida Fernández , José Luís Fernández-Puentes. "Preparation of varioline B derivatives as antitumor agents" (2002) WO 2002012240.

Mercedes Álvarez, Lidia Feliu, José Luís Fernández-Puentes, Dolores García. "New Cytotoxic pyrido[2,3,4-kl]acridine derivatives, their preparation and their therapeutic use". (2002) US, 6559, 161 B1.

Fernando Albericio, Ernest Giralt, Jose C. Jiménez, Angel López, Ignacio Manzanares, Ignacio Rodriguez, Miriam Royo. "Preparation of Kahalalide Compounds". PCT Int. Appl. (2001), WO20011058934, CAN 135: 167039. Pharma Mar S.A. EE.CC.

Miriam Royo, María del Fresno, Cristina Carreño, Fernando Albericio, Carolina García, Antonio Ferrer-Montiel. "Hidantoinas guanidiladas capaces de bloquear la respuesta a sustancias químicas o estímulos térmicos o mediadores de la inflamación de los nociceptores, y composiciones que los contienen". PCT (2001) ES 200102379, Diver DrugsS.L. España.

Mercedes Álvarez, Lidia Feliu, José Luís Fernández-Puentes, Dolores García. "New Cytotoxic pyrido[2,3,4-kl]acridine derivatives, their preparation and their therapeutic use". (2001) WO 01/09133 A1.

Knud J. Jensen, Georges Barany, Micheal F. Songster, Jordi Alsina, Josef Vágner, Fernando Albericio. "Backbone amide (BAL) anchoring in solid-phase peptide synthesis". PCT Int. Appl. (1999) US 5917015, CAN 131: 73977. University of Minnesota-PE Biosystems. USA, EE.CC, Japan.

George Barany, Fernando Albericio, Nuria A.Sole, Jane Chang, Samuel Zalipsky. “Polyethylene glycol derivatives for solid-phase peptide synthesis” U.S. (1996), Cont.-in-part of U.S. Ser. No. 59,626. US 91-715289 19910614; WO 91-US6103 19910827; US 91-760768 19910916; US 93-59626 19930519. CAN 125:223972. University of Minnesota, USA.

Ernest Giralt, Fernando Albericio, Paul Lloyd-Williams, Isabel González-Valcarcel, Gemma Jou, Andres Gómez, Ignacio Manzanares. "Procedimiento de preparación de Didemnina A". PCT (1995) ES 2102322, CAN 128: 180667, Pharma Mar S.A., España.

Berta Ponsati, Antonio Parente, Jose M. García-Antón, David Andreu, Fernando Albericio. "Procedimiento de síntesis en fase sólida de calcitonina de salmón". PCT (1993) ES 9301330. Lipotec, S.A. España.

Fernando Albericio, Steven A. Kates. "Automated allyl cleavage for solid-phase synthesis of peptides" PCT Int. Appl. (1993) US93-45273. CAN 122:161366. Millipore Corporation. USA, EE.CC, Japan.

George Barany, Fernando Albericio. "Preparation of hypersensitive acid-labile handle for solid-phase peptide synthesis". PCT Int. Appl. (1993) US 5196566, CAN 119: 139796. University of Minnesota-Millipore Corporation. USA, EE.CC, Japan.

George Barany, Fernando Albericio, Nuria A. Solé, Jane Chang, Samuel Zalipsky. "Polyethylene glycol derivatives for solid-phase applications". PCT Int. Appl. (1992), WO 9204384, CAN 117: 172114. University of Minnesota-Millipore Corporation. USA, EE.CC, Japan

University of Barcelona (UB) - Barcelona Science Park (PCB) C/Baldiri Reixac, 10-12, 08028 Barcelona