Regulation of gene expression

Montserrat Corominas

Publications


Selected Publications

Camilleri-Robles C, Serras F, Corominas M. Role of D-GADD45 in JNK-Dependent Apoptosis and Regeneration in Drosophila. Genes (Basel). 2019 May 18;10(5). pii: E378. doi: 10.3390/genes10050378.

Vizcaya-Molina E, Klein CC, Serras F, Corominas M. Chromatin dynamics in regeneration epithelia: Lessons from Drosophila imaginal discs. Semin Cell Dev Biol. 2019 May 16. pii: S1084-9521(18)30195-2. doi: 10.1016/j.semcdb.2019.04.017.

Santabárbara-Ruiz P, Esteban-Collado J, Pérez L, Viola G, Abril JF, Milán M, Corominas M, Serras F. Ask1 and Akt act synergistically to promote ROS-dependent regeneration in Drosophila. PLoS Genet. 2019 Jan 24;15(1):e1007926

Vizcaya-Molina E, Klein CC, Serras F, Mishra RK, Guigó R, Corominas M. Damage-responsive elements in Drosophila regeneration. Genome Res. 2018 Dec;28(12):1852-1866.

Doumpas N, Ruiz-Romero M, Blanco E, Edgar B, Corominas M, Teleman AA. Brk regulates wing disc growth in part via repression of Myc expression. EMBO Rep. 2013 Mar 1;14(3):261-8. doi: 10.1038/embor.2013.1

Perez-Lluch, S., Guigo, R. and Corominas, M. Active transcription without histone modifications. Oncotarget. 2015 Dec 8;6(39):41401. doi: 10.18632/oncotarget.6437

Santabárbara-Ruiz P, López-Santillán M, Martínez-Rodríguez I, Binagui-Casas A, Pérez L, Milán M, Corominas M, Serras F. ROS-Induced JNK and p38 Signaling Is Required for Unpaired Cytokine Activation during Drosophila Regeneration. PLoS Genet. 2015 Oct 23;11(10):e1005595. doi: 10.1371/journal.pgen.1005595.

Pérez-Lluch S, Blanco E, Tilgner H, Curado J, Ruiz-Romero M, Corominas M, Guigó R. Absence of canonical marks of active chromatin in developmentally regulated genes. Nat Genet. 2015 Oct;47(10):1158-67. doi: 10.1038/ng.3381

Mariotti M, Santesmasses D, Capella-Gutierrez S, Mateo A, Arnan C, Johnson R, D'Aniello S, Yim SH, Gladyshev VN, Serras F, Corominas M, Gabaldón T, Guigó R. Evolution of selenophosphate synthetases: emergence and relocation of function through independent duplications and recurrent subfunctionalization. Genome Res. 2015 Sep;25(9):1256-67. doi: 10.1101/gr.190538.115.

Ruiz-Romero M, Blanco E, Paricio N, Serras F, Corominas M. Cabut/dTIEG associates with the transcription factor Yorkie for growth control. EMBO Rep.2015 Mar;16(3):362-9. doi: 10.15252/embr.201439193.

Alaña L, Sesé M, Cánovas V, Punyal Y, Fernández Y, Abasolo I, de Torres I, Ruiz C, Espinosa L, Bigas A, Y Cajal SR, Fernández PL, Serras F, Corominas M, Thomson TM, Paciucci R. Prostate tumor OVerexpressed-1 (PTOV1) down-regulates HES1 and HEY1 notch targets genes and promotes prostate cancer progression. Mol Cancer. 2014 Mar 31;13:74. doi: 10.1186/1476-4598-13-74.

Turkel N, Sahota VK, Bolden JE, Goulding KR, Doggett K, Willoughby LF, Blanco E, Martin-Blanco E, Corominas M, Ellul J, Aigaki T, Richardson HE, Brumby AM. The BTB-zinc finger transcription factor abrupt acts as an epithelial oncogene in Drosophila melanogaster through maintaining a progenitor-like cell state. PLoS Genet. 2013;9(7):e1003627. doi: 10.1371/journal.pgen.1003627.

Carbonell A, Mazo A, Serras F, Corominas M. Ash2 acts as an ecdysone receptor coactivator by stabilizing the histone methyltransferase Trr. Mol Biol Cell. 2013 Feb;24(3):361-72. doi: 10.1091/mbc.E12-04-0267.

Mora N, Almudi I, Alsina B, Corominas M, Serras F. β amyloid protein precursor-like (Appl) is a Ras1/MAPK-regulated gene required for axonal targeting in Drosophila photoreceptor neurons. J Cell Sci. 2013 Jan 1;126(Pt 1):53-9. doi: 10.1242/jcs.114785.

Blanco E, Corominas M. CBS: an open platform that integrates predictive methods and epigenetics information to characterize conserved regulatory features in multiple Drosophila genomes. BMC Genomics. 2012 Dec 10;13:688. doi: 10.

Lloret-Llinares M, Pérez-Lluch S, Rossell D, Morán T, Ponsa-Cobas J, Auer H, Corominas M, Azorín F. dKDM5/LID regulates H3K4me3 dynamics at the transcription-start site (TSS) of actively transcribed developmental genes. Nucleic Acids Res. 2012 Oct;40(19):

Pérez-Lluch S, Blanco E, Carbonell A, Raha D, Snyder M, Serras F, Corominas M. Genome-wide chromatin occupancy analysis reveals a role for ASH2 in transcriptional pausing. Nucleic Acids Res. 2011 Jun;39(11):4628-39. doi: 10.1093/nar/gkq1322.

Repiso A, Bergantiños C, Corominas M, Serras F. Tissue repair and regeneration in Drosophila imaginal discs. Dev Growth Differ. 2011 Feb;53(2):177-85. doi: 10.1111/j.1440-169X.2010.01247.x.

Almudi I, Corominas M, Serras F. Competition between SOCS36E and Drk modulates Sevenless receptor tyrosine kinase activity. J Cell Sci. 2010 Nov 15;123(Pt 22):3857-62. doi: 10.1242/jcs.071134.

Blanco E, Ruiz-Romero M, Beltran S, Bosch M, Punset A, Serras F, Corominas M. Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. BMC Dev Biol. 2010 Sep 2;10:94. doi: 10.118

Bergantiños C, Corominas M, Serras F. Cell death-induced regeneration in wing imaginal discs requires JNK signalling. Development. 2010 Apr;137(7):1169-79. doi: 10.1242/dev.045559.

Bergantiños C, Vilana X, Corominas M, Serras F. Imaginal discs: Renaissance of a model for regenerative biology. Bioessays. 2010 Mar;32(3):207-17. doi: 10.1002/bies.200900105.

Pignatelli M, Serras F, Moya A, Guigó R, Corominas M. CROC: finding chromosomal clusters in eukaryotic genomes. Bioinformatics. 2009 Jun 15;25(12):1552-3. doi: 10.1093/bioinformatics/btp248.

Almudi I, Stocker H, Hafen E, Corominas M, Serras F. SOCS36E specifically interferes with Sevenless signaling during Drosophila eye development. Dev Biol. 2009 Feb 1;326(1):212-23. doi: 10.1016/j.ydbio.2008.11.014.

Ryder E, Ashburner M, Bautista-Llacer R, Drummond J, Webster J, Johnson G, Morley T, Chan YS, Blows F, Coulson D, Reuter G, Baisch H, Apelt C, Kauk A, Rudolph T, Kube M, Klimm M, Nickel C, Szidonya J, Maróy P, Pal M, Rasmuson-Lestander A, Ekström K, Stocker H, Hugentobler C, Hafen E, Gubb D, Pflugfelder G, Dorner C, Mechler B, Schenkel H, Marhold J, Serras F, Corominas M, Punset A, Roote J, Russell S. The DrosDel deletion collection: a Drosophila genomewide chromosomal deficiency resource. Genetics. 2007 Sep;177(1):615-29.

Sesé M, Corominas M, Stocker H, Heino TI, Hafen E, Serras F. The Cdi/TESK1 kinase is required for Sevenless signaling and epithelial organization in the Drosophila eye. J Cell Sci. 2006 Dec 15;119(Pt 24):5047-56.

Dunlop J, Morin X, Corominas M, Serras F, Tear G. glaikit is essential for the formation of epithelial polarity and neuronal development. Curr Biol. 2004 Nov 23;14(22):2039-45.

Angulo M, Corominas M, Serras F. Activation and repression activities of ash2 in Drosophila wing imaginal discs. Development. 2004 Oct;131(20):4943-53.

Morey M, Corominas M, Serras F. DIAP1 suppresses ROS-induced apoptosis caused by impairment of the selD/sps1 homolog in Drosophila. J Cell Sci. 2003 Nov 15;116(Pt 22):4597-604.

Alsina B, Corominas M, Berry MJ, Baguñà J, Serras F. Disruption of selenoprotein biosynthesis affects cell proliferation in the imaginal discs and brain of Drosophila melanogaster. J Cell Sci. 1999 Sep;112 ( Pt 17):2875-84.