Members  of the group:

Àngel González-Sistal, M.D., PhD. Titular professor of Physiology. Head of group

Alicia Baltasar Sánchez, M.D., Fundació Bosch i Gimpera Researcher. UB

Research lines:

·        Analysis of Biomedical Images (code UNESCO 2406.06)

·        Nuclear Medicine (code UNESCO 3204.01)

·        Digital Computation (code UNESCO 1203.13)

·        Physiological Systems Modelling

Speciffic Applications

Processing and analysis of medical images:

Healthy bone characterization.

Improvement of skeletal  metastases diagnosis.

Techniques: - Plain x-ray and digital radiography.

                      - Scintigraphy

                      - Image: enhancement, filtering

                     - Parametric quantification and characterization

                     - Segmentation

                     - Morphometry

                     -  Computer assisted radiology

Processing and analysis of neurobiological signals:

Study of the cholinergic synaptic transmission. ATP release.

Techniques:  -Chemiluminescence and Deconvolution.

                       -Biosignal processing for data acquisition

                      - Signals: filtering, FFT

                     - Computer applications.

Financial support:

‘Connexins and ATP release. Role in the pathogenesis of X-linked Charcot Marie Tooth disease.’.

 SAF2005-00736. Programa Nacional de Promoción General del Conocimiento. Comisión Interministerial de Ciencia y Tecnología (CICYT). 2005-2008

‘Bone tumors analysis by digitized image processing’

Fundació Universitària Agustí Pedro i Pons. Universitat de Barcelona. 2006-2008

‘Computed Method for the detection of osteoblastic metastases’

Proof-of-Concept Programme (PPV045/07).  AVCRI - Universitat de Barcelona / Grupo Santander. 2008- 2009

Publications:

Baltasar Sánchez A, González-Sistal A (2005) Evaluation of Healthy Bone by a Method Based on Image Analysis. In: Mendez-Vilas A (ed), Recent Advances in Multidisciplinary Applied Physics, Elsevier Science, Oxford, pp: 683-688.

Baltasar Sánchez A, González-Sistal A (2005) A Method to Improve the Characterization of Bone Tumors from Digitalized Radiographs. In: Mendez-Vilas A (ed), Recent Advances in Multidisciplinary Applied Physics, Elsevier Science, Oxford, pp: 689-694.

González-Sistal, A.; Baltasar Sánchez, A. Assessment of Mean Gray Level Parameter. Usefulness of Healthy Skeletal Radiographs. Biomedizinische Technik 2005, 50 suppl. vol.1 (2): 1396- 1397   

González-Sistal, A.; Baltasar Sánchez, A.  A Complementary Method for the Detection of Osteoblastic Metastases on Digitized Radiographs.  Journal of Digital Imaging 2006, 12 (3): 270- 275   

González-Sistal, A. Diagnostic Imaging Modalities of Osteoblastic Metastases. Hospital Imaging & Radiology Europe 2007, 2 (1): 16-17

González-Sistal A, Reigada D, Puchal R, Gómez de Aranda I, Elias M, Marsal J, Solsona C. Ionic dependence of the velocity of release of ATP from permeabilized cholinergic synaptic vesicles. Neuroscience 2007,  149 (2): 251-255 

González- Sistal, A. Tribuna. Reorientar el diagnóstico. Diario Médico. 13 /04/2007.

Paper: Year 15, num. 3401, pp: 20.Online: http://www.diariomedico.com