Departament de Genètica 


EVOLUTIONARY GENETICS

Montserrat Aguadé
Ricard Albalat
Neus Cols
Elvira Juan
Francesc Mestres
Montserrat Papaceit
Marta Pascual
Julio Rozas
Carmen Segarra
Lluís Serra

NEUS COLS


contact
bio
research
publications


SELECTED DE PUBLICATIONS



Articles

Leiva-Presa, A., , Capdevila, M., Cols, N., Atrian, S., Gonzàlez-Duarte, P. Chemical foundation of the attenuation of methylmercury (II) cytotoxicity by metallothioneins. Eur J Biochem. 2004, 271: 1-6

Cols, N.; Roepstorff, K.; Gonzàlez-Duarte, R.; Atrian, S. Secretion of mouse metallothionein by engineered E.coli in metal enriched culture media.J Mol Microbiol Biotechnol. 2001, 3: 507-512

Bofill, R.; Capdevila, M.; Cols, N.; Atrian, S.; Gonzàlez-Duarte, P.Zinc (II) is required for the in vivo and in vitro folding of mouse copper metallothionein in two domains.J Biol Inorg Chem. 2001, 6: 405-417

Oppermann, M.; Cols, N.; Nyman, T.; Helin, J.; Saarien, J.; Byman, I.; Toran, N.; Alaiya, A.A.; Bergman, T.; Kalkkien, N.; Gonzàlez-Duarte, R.; Jörnvall, H.Identification of foetal brain proteins by two-dimensional electrophoresis and mass spectrometry: comparison of normal and Down syndrome samples. Eur J Biochem. 2000, 267: 4713-4719

Cols, N.; Romero-Isart, N.; Bofill, R.; Capdevila, M.; Gonzàlez-Duarte, P.; Gonzàlez-Duarte, R.; Atrian S.In vivo copper and cadmium binding ability of mammalian metallothionein b domain.Protein Eng. 1999, 12: 265-269

Bofill, R.; Palacios, O.; Capdevila, M.; Cols, N.; Gonzàlez-Duarte, R.; Atrian, S.; Gonzàlez-Duarte, P. A new insight into de Ag+ and Cu+ binding sites in the metallothionein b domain. J Inorg Biochem. 1999, 73: 57-64

Romero-Isart, N.; Cols, N.; Termansen, M.K.; Gelpí, J.Ll.; Gonzàlez-Duarte, R.; Atrian, S.; Capdevila, M.; Gonzàlez-Duarte, P. Replacement of terminal cysteine with histidine in the metallothionein a and b domains mantains its binding capacity. Eur J Biochem. 1999, 259: 519-527

Capdevila, M.; Cols, N.; Romero, N.; Gonzàlez-Duarte, R.; Atrian, S.; Gonzàlez-Duarte, P. Recombinant synthesis of mouse Zn3-b and Zn4-a metallothionein 1. Subunits and characterization of their cadmium (II) binding capacity.Cell Mol Life Sci. 1997, 53: 681-688

Cols, N.; Capdevila, M.; Romero, N.; Oliva, B.; Gonzàlez-Duarte, P.; Gonzàlez-Duarte, R.; Atrian S. Binding of excess cadmium (II) to Cd7-metallothionein from recombinant mouse Zn7-metallothionein. J Inorg Biochem. 1997, 68: 157-166

Cols, N.; Atrian, S.; Benach, J.; Ladenstein, R.; Gonzàlez-Duarte, R.Drosophila alcohol dehydrogenase: Evaluation of Ser139 site-directed mutants.FEBS Lett. 1997, 413:191-193

Capdevila, M.; Romero, N.; Gonzàlez-Duarte, P.; Cols, N.; Atrian, S.; Gonzàlez-Duarte, R.; Stillman, M.J.Cadmium (II) binding to recombinant mouse Zn3-b metallothionein 1. Anales de Química- International Edition.1996, 92: 199-201

Atrian, S.; Capdevila, M.; Cols, N.; Gonzàlez-Duarte, R.; Gonzàlez-Duarte, P.; Romero, N.; Stillman, M.J. Metal binding properties of recombinant metallothionein and related peptides. J Inorg Biochem. 1995, 59: 103

Cols, N.; Marfany, G.; Atrian, S.; Gonzàlez-Duarte, R. Effects of site-directed mutagenesis on conserved positions of Drosophila alcohol dehydrogenase. FEBS Lett. 1993, 319: 90-94

García-Calderón, P.A.; Engel, P.; Cols, N.; Heredia García, C.D. Immune complexes in retinitis pigmentosa. Ophthalmic Paediatr Genet. 1984, 4: 199-202

Engel, P.; Huguet, J.; Sanosa, J.; Sierra, P.; Cols, N.; García-Calderón, P.A. T cell subsets in allergic respiratory disease using monoclonal antibodies. Ann Allergy. 1984, 53: 337-340

Heredia, C.D.; Huguet, J.; Cols, N.; Engel, P.; García-Calderón, P.A. Immune complexes in retinitis pigmentosa. Br J Ophthalmol. 1984, 68: 811-814

Soler, A.; Salami, C.; Balmes, I.; Carrió, A.; Tejada, I.; Farguell, T.; Cols, N.; Cararach, J.; Fortuny, A. Pericentric inversion of the X chromosome in a family. Clin Genet 1981, 20: 234-235


Book chapters

Atrian, S.; Bofill, R.; Capdevila, M.; Cols, N.; Gonzàlez-Duarte, P.; Gonzàlez-Duarte, R. Recombinant synthesis and metal-binding abilities of mouse metallothionein 1 and its a and b domains. In Metallothionein IV. Klaassen Ed. Birhauser, 55-61, 1999