Personal details   Family name: MARTINEZ-HEREDIA       Given Name: JUAN DNI (ID): 47648622           Date of birth: 06/April/1979                  E-mail:jmartinezheredia@ub.edu

 

Academic studies

 

Batchelor Degree in Biological Sciences, Biotechnology specialization by University of Barcelona Date: 2003

Doctorate: January 2008. Human sperm proteomic characterization. Differential proteins found in asthenozoospermic patients.

Dissertation Director: Rafael Oliva Virgili

 

 

Actual position

 

Working at Human Genetics Lab, from University of Barcelona.

 

Previous activities

 

Echevarne Laboratory

July 2002 – December 2002 Human sperm analysis using CASA technology. Also, look for information about the seminal characteristic of several animals (dog, cat, bull, pig, horse, rabbit) and preparation of a protocol to study this animal seminal characteristics using CASA technology.

Human Genetic Lab

PhD studies in Human Genetic Lab; during these years, I have used to work with proteomic tools, like 2D gels and silver and DIGE stains. Also, I have gained knowledgement about  PDQuest software, Cluster&TreeView software, Pathway Assist and Office package.

 

 

Participation in funded projects

1.- Project Title: Molecular and proteomic characterization of sperm cells from infertile patients and controls (BMC2003-03937)

Financing Entity: Ministerio de Educación y Ciencia

Duration, from: 2004      to: 2006                       

Principal Researcher: Dr. Rafael Oliva Virgili

2.- Project Title: Proteomics from infertil patients’s sperm, in knock out models and mechanism of the nucleohistone-nucleoprotamine transition. (BFU2006-03479/BNC)

Financial Entity: Ministerio de Educación y Ciencia.

Duration, from: 2006      to: 2008

Principal Researcher: Dr. Rafael Oliva Virgili

Research articles

1.- Martínez-Heredia J, Estanyol JM, Ballescà JL, Oliva R. Proteomic identification of human sperm proteins. Proteomics, 2006 Aug; 6(15):4356-69. Impact Factor: 5.7

2.- Oliva R, Martinez-Heredia J, de Mateo S, Gazquez C, Oriola J, Estanyol JM, Guimera M, Balasch J, Ballesca JL. Proteomics of human spermatozoa, protamine content and assisted reproduction outcome. In: Spermatology (Roldan, Gomendio, Eds), Nottingham University Press. Series of the "Society for Reproduction and Fertility". 2007. ISBN 1-904761-48-8. Soc Reprod Fertil Suppl. 2007; 65:527-30.

3.- Martínez-Heredia J, de Mateo S, Vidal Taboada J, Estanyol JM, Ballescà JL, and Oliva R. Identification
of proteomic differences in asthenozoospermic sperm samples. Human Reproduction, 2008 Feb; 15. Impact Factor: 3.7

4.- de Mateo S, Martínez-Heredia J, Estanyol JM, Domíguez-Fandos D, Vidal-Taboada JM, Ballescà JL and Oliva R. Marked correlations in protein expression identified by proteomic analysis of human spermatozoa. Proteomics. 2007 Dec;7(23):4264-77. Impact Factor: 5.7

5.- Oliva R, Martínez-Heredia J, Estanyol JM. Proteomics in the study of the sperm cell composition, differentiation and function. In press in Systems Biology in Reproductive Medicine (Formerly called Archives of Andrology). Impact Factor: 0.6

6.- Mathivanan S,… Martínez-Heredia J, …, Pandey A. Human Proteinpedia: A portal for sharing and integration of human protein data. Nature Biotechnology, 2008 Feb; 26(2):164-7. Impact Factor: 22.7

 

Conference Contributions

1.- Oliva R, Mengual L, de Llanos M, Martínez-Heredia J, Ballescà JL. Title: Differences in P1/P2 ratios and in nuclear proteins content in sperm from infertile patients and controls. Poster presentation. Congress: Genetics of male infertility: from research to clinic, European Association of Andrology, International Symposium. Florence, Italy. Date: 2-4/10/03

2.- Martínez-Heredia J, Holub K, Fontanet A, Ballesca JL, and Oliva R. Title: Increased polymorphism of the mitochondrial DNA polymerase gamma gene (POLG) among asthenozoospermic patients. Poster presentation. Congress: European Journal of Human Genetics Publication: European Journal of Human Genetics, vol 12, Suppl 1, June 2004-12-17

3.- Oliva R, Martínez-Heredia J, Domínguez D, Torregrosa N, Mengual L, Ballescà JL.  Title: Proteomics of human male infertility. Poster presentation. Congress: VIth European Symposium of The Protein Society. Barcelona, Spain. Date: 30/04/05 to 04/05/05

4.- Martínez-Heredia J, Torregrosa N, Domínguez D, Estanyol JM, Ballescà JL, Oliva R. Title: Proteomic analysis of spermatozoa from asthenozoospermic or normozoospermic patients. Poster Presentation. Congress: International Workshop of Molecular Andrology. Giessen, German. Date: 7-9/10/05

5.- Oliva R, Martínez-Heredia J, de Mateo S, Gázquez C,Oriola J, Estanyol JM, Guimerà M, Balasch J, Ballescà JL. Title: Proteomics of human spermatozoa, protamine content and assisted reproduction outcome. Congress:10th International Symposium in Spermatology (Spermadrid), Madrid, Spain. Date: 17-22/09/06

6.- De Mateo S, Martínez-Heredia J, Domínguez-Fandos D, Estanyol JM, Ballescà JL, Oliva R. Title: Protamine content and proteomics of the human spermatozoa. Congress: BAS 2006 Annual Meeting, Leeds, UK. Date:  15-18/11/06

Presentations

1.- Martínez-Heredia J, Torregrosa N, Domínguez D, Estanyol JM, Mengual L, Ballescà JL, Oliva R. Title: Proteomic analysis of sperm from asthenozoospermic and normozoospermic patients (in Catalan). Oral presentation. Congress: IX Jornades de Biologia de la Reproducció, Barcelona, Spain. Date: 26/05/05

2.- Martínez-Heredia J, Estanyol JM, Ballescà JL, Oliva R. Title: Proteomic identification of sperm proteins from asthenozoospermic and normozoospermic patients. Oral presentation. Congress: European Testis Workshop 2006. Bad Aibling, German. Date: 22-26/04/2006

3.- Martínez-Heredia J, de Mateo S, Gázquez C, Oriola J, Estanyol JM, Guimerà M, Balasch J, Ballescà JL, Oliva R. Title: Proteomics of human spermatozoa in infertile patients and in controls. Oral presentation. Congress: Perspectives in Proteomics. Barcelona, Spain. Date: 30/06/06

4.- Martínez-Heredia J, de Mateo S, Vidal-Taboada JM, Ballescà JL, Oliva R. Title: Proteic expression differences between asthenozoospermics and normozoospermics patients samples. Oral presentation. Congress: X Jornades de Biologia de la Reproducció, Barcelona, Spain. Date: 25/04/07.

Fellowships

1.. Fellowship to finish the thesis, from UB. 2007.

References

Dr Rafael Oliva, Professor, Faculty of Medicine, University of Barcelona.

Casanova 143, 08036, Barcelona. Phone Number: +34934021877

E-mail: roliva@ub.edu