Hepatitis A
Genetic and antigenic characterisation of hepatitis A virus.

Gastroenteritis viruses

· Astroviruses. Molecular epidemiology of astroviruses.
Molecular and biological characterisation of protein nsP1a4.
Astrovirus morphogenesis.

· Rotaviruses. Molecular epidemiology of rotaviruses.

· Noroviruses. Molecular epidemiology of noroviruses.

Environmental virology.
Molecular environmental epidemiology of viruses in sewage.
Virus survival in the environment.
Virus disinfection. Development of methodologies for the
detection of viruses in environmental samples.

Food virology.
Development of standardised quantitative methodologies for the detection of viruses in food samples, in particular molluscan shellfish.

Virological safety of drugs purified from human or animal sources.
Virological determinations in viral safety validation studies.
Studies on the efficacy of antiviral agents.
All procedures are performed in compliance with GLP standards.

Official funding in the last 10 years.

European Commission.
Grant QLRT-1999-0594, Quality Of Life And Management Of Living Resources, Rapid detection of transnational foodborne viral infections and elucidation of transmission routes through molecular tracing and development of a common
database, 1999-2002.

Grant QLRT-1999-0634, Quality Of Life And Management Of Living Resources, Virus-safe seafood, 1999-2002.

Grant ERB IC15-CT98-0326, INCO-Copernicus, Blood sterilization using the photodynamic effect with immobilized photosensitizers,1998-2001.

Grant ERB3514PL973098, INCO, Isolation, characterization and molecular cloning of variants of hepatitis A in South America, and expression of antigens involved in virus neutralization by recombinant DNA techniques, 1999-2000.

Spanish government.

Grant BIO2002-02625, MCyT, Molecular diagnosis of hepatitis A virus and studies on genetic variability and structural stability. 2002-2004.

Spanish-Italian Integrated Action HI1999-0028, Enteric viruses in environmental and clinical samples from Albania, 1999-2001.

Grant BIO99-0455, CICYT, Diagnosis, and genetic and antigenic charaterisation of wild-tipe and variant HAV strains, 1999-2002.

Grant 98-0256, CDTI, New technologies in virus inactivation, 1998-2001.

Grant 98-0030, CDTI, Study of virus removal in one step of the production of ganglioside from human tumoral cells, 1998.

Grant BIO95-0061, CICYT, Production and evaluation of synthetic and recombinant immunogens of hepatitis A virus as constituents of a vaccine, 1995-1998.

Grant BIO92-0982, CICYT, Production and evaluation of chemosynthetic and biosynthetic immunogens of hepatitis A virus, 1992-1995.

Catalonian government.

Grant 2001SGR00098, Enteric Virus Research Group, 2001-2004.

Grant 1999SGR00022, Enteric Virus Research Group, 1999-2001.

Grant 1997SGR00224, Enteric Virus Research Group, 1997-1999.

Grant 1995SGR00197, Enteric Virus Research Group, 1995-1997.