Introduction

This group is part of the “Alberto Sols” Institute of Biomedical Research, a joint center of the National Research Council (CSIC) and the Autonomous University of Madrid. Its research activity focuses on the study of the molecular mechanisms by which nuclear receptors, particularly thyroid hormone receptors (TRs), affect several pathophysiological processes such as inflammation, tumorigenesis, and cellular reprogramming. Recent results from this group indicate that the NCoR (nuclear corepressor) is an important mediator of the antitumor and antimetastatic effects of TRs, and that these receptors inhibit the development of fibrotic processes.