Research
Interests
Current
Projects
Selected Recent Publications
Adenosine A1 receptor protein levels and activity is increased in the cerebral
cortex in Creutzfeldt-Jakob disease and in bovine spongiform
encephalopathy-infected bovine-PrP mice.
Rodriguez A, Martin M, Albasanz JL, Barrachina M, Espinosa JC, Torres JM,
Ferrer I.
J Neuropathol Exp Neurol. 2006 Oct;65(10):964-75.
Lysosome-associated membrane protein 1 (LAMP-1) in Alzheimer's disease.
Barrachina M, Maes T, Buesa C, Ferrer I.
Neuropathol Appl Neurobiol. 2006 Oct;32(5):505-16.
TaqMan PCR assay in the control of RNA normalization in human post-mortem brain
tissue.
Barrachina M, Castano E, Ferrer I.
Neurochem Int. 2006 Aug;49(3):276-84. Epub 2006 Mar 7.
Reduced ubiquitin C-terminal hydrolase-1 expression levels in dementia with
Lewy bodies.
Barrachina M, Castano E, Dalfo E, Maes T, Buesa C, Ferrer I.
Neurobiol Dis. 2006 May;22(2):265-73. Epub 2005 Dec 27.
Constitutive Dyrk1A is abnormally expressed in Alzheimer disease, Down
syndrome, Pick disease, and related transgenic models.
Ferrer I, Barrachina M, Puig B, Martinez de Lagran M, Marti E, Avila J,
Dierssen M.
Neurobiol Dis. 2005 Nov;20(2):392-400.
Induction of C/EBP beta and GADD153 expression by dopamine in human
neuroblastoma cells. Relationship with alpha-synuclein increase and cell damage.
Gomez-Santos C, Barrachina M, Gimenez-Xavier P, Dalfo E, Ferrer I, Ambrosio S.
Brain Res Bull. 2005 Feb 15;65(1):87-95.
Amyloid-beta deposition in the cerebral cortex in Dementia with Lewy bodies is
accompanied by a relative increase in AbetaPP mRNA isoforms containing the
Kunitz protease inhibitor.
Barrachina M, Dalfo E, Puig B, Vidal N, Freixes M, Castano E, Ferrer I.
Neurochem Int. 2005 Feb;46(3):253-60. Epub 2004 Nov 14.
DNA chip technology in brain banks: confronting a degrading world.
J Neuropathol Exp Neurol. 2004 Oct;63(10):1003-14. Review.
Buesa C, Maes T, Subirada F, Barrachina M, Ferrer I.
Abnormal alpha-synuclein interactions with rab3a and rabphilin in diffuse Lewy
body disease.
Dalfo E, Barrachina M, Rosa JL, Ambrosio S, Ferrer I.
Neurobiol Dis. 2004 Jun;16(1):92-7.
Abnormal alpha-synuclein interactions with Rab proteins in alpha-synuclein A30P
transgenic mice.
Dalfo E, Gomez-Isla T, Rosa JL, Nieto Bodelon M, Cuadrado Tejedor M,
Barrachina M, Ambrosio S, Ferrer I.
J Neuropathol Exp Neurol. 2004 Apr;63(4):302-13.
Neuroprotective effect of citicoline in 6-hydroxydopamine-lesioned rats and in
6-hydroxydopamine-treated SH-SY5Y human neuroblastoma cells.
Barrachina M, Dominguez I, Ambrosio S, Secades J, Lozano R, Ferrer I.
J Neurol Sci. 2003 Nov 15;215(1-2):105-10.
Dopamine induces autophagic cell death and alpha-synuclein increase in human
neuroblastoma SH-SY5Y cells.
Gomez-Santos C, Ferrer I, Santidrian AF, Barrachina M, Gil J, Ambrosio S.
J Neurosci Res. 2003 Aug 1;73(3):341-50.
Phosphorylated protein kinases associated with neuronal and glial tau deposits
in argyrophilic grain disease.
Ferrer I, Barrachina M, Tolnay M, Rey MJ, Vidal N, Carmona M, Blanco R,
Puig B.
Brain Pathol. 2003 Jan;13(1):62-78.
Citicoline increases glutathione redox ratio and reduces caspase-3 activation
and cell death in staurosporine-treated SH-SY5Y human neuroblastoma cells.
Barrachina M, Secades J, Lozano R, Gomez-Santos C, Ambrosio S, Ferrer I.
Brain Res. 2002 Dec 6;957(1):84-90.
Anti-tau phospho-specific Ser262 antibody recognizes a variety of abnormal
hyper-phosphorylated tau deposits in tauopathies including Pick bodies and
argyrophilic grains.
Ferrer I, Barrachina M, Puig B.
Acta Neuropathol (Berl). 2002 Dec;104(6):658-64. Epub 2002 Aug 30.
Glycogen synthase kinase-3 is associated with neuronal and glial
hyperphosphorylated tau deposits in Alzheimer's disease, Pick's disease,
progressive supranuclear palsy and corticobasal degeneration.
Ferrer I, Barrachina M, Puig B.
Acta Neuropathol (Berl). 2002 Dec;104(6):583-91. Epub 2002 Jul 13.
MPP+ increases alpha-synuclein expression and ERK/MAP-kinase phosphorylation in human neuroblastoma SH-SY5Y cells.
Gomez-Santos C, Ferrer I, Reiriz J, Vinals F, Barrachina M, Ambrosio S.
Brain Res. 2002 May 10;935(1-2):32-9.
CDP-choline reduces pro-caspase and cleaved caspase-3 expression, nuclear DNA
fragmentation, and specific PARP-cleaved products of caspase activation
following middle cerebral artery occlusion in the rat.
Krupinski J, Ferrer I, Barrachina M, Secades JJ, Mercadal J, Lozano R.
Neuropharmacology. 2002 May;42(6):846-54.
Active, phosphorylation-dependent mitogen-activated protein kinase (MAPK/ERK),
stress-activated protein kinase/c-Jun N-terminal kinase (SAPK/JNK), and p38
kinase expression in Parkinson's disease and Dementia with Lewy bodies.
Ferrer I, Blanco R, Carmona M, Puig B, Barrachina M, Gomez C, Ambrosio S.
J Neural Transm. 2001;108(12):1383-96.
