Vanesa Soto Cerrato Assistant Professor of Cell Biology Professor Ajudant de Biologia Cel.luar E-mail: vsoto@ub.edu Phone: +3493 4024288

Research Interests

Current Projects

Selected Recent Publications

Proteomic analysis of prodigiosin-induced apoptosis in a breast cancer mitoxantrone-resistant (MCF-7 MR) cell line.
Monge M, Vilaseca M, Soto-Cerrato V, Montaner B, Giralt E, Perez-Tomas R. 
Invest New Drugs. 2006 Apr 5; [Epub ahead of print] 
 
Cell cycle arrest and proapoptotic effects of the anticancer cyclodepsipeptide serratamolide (AT514) are independent of p53 status in breast cancer cells.
Soto-Cerrato V, Montaner B, Martinell M, Vilaseca M, Giralt E, Perez-Tomas R. 
Biochem Pharmacol. 2005 Dec 19;71(1-2):32-41. Epub 2005 Nov 18. 
 
High cytotoxic sensitivity of the human small cell lung doxorubicin-resistant carcinoma (GLC4/ADR) cell line to prodigiosin through apoptosis activation.
Llagostera E, Soto-Cerrato V, Joshi R, Montaner B, Gimenez-Bonafe P,Perez-Tomas R. 
Anticancer Drugs. 2005 Apr;16(4):393-9. 
 
AT514, a cyclic depsipeptide from Serratia marcescens, induces apoptosis of B-chronic lymphocytic leukemia cells: interference with the Akt/NF-kappaB survival pathway.
Escobar-Diaz E, Lopez-Martin EM, Hernandez del Cerro M, Puig-Kroger A,Soto-Cerrato V, Montaner B, Giralt E, Garcia-Marco JA, Perez-Tomas R, Garcia-Pardo A. 
Leukemia. 2005 Apr;19(4):572-9. 
 
Mitochondria-mediated apoptosis operating irrespective of multidrug resistance in breast cancer cells by the anticancer agent prodigiosin.
Soto-Cerrato V, Llagostera E, Montaner B, Scheffer GL, Perez-Tomas R. 
Biochem Pharmacol. 2004 Oct 1;68(7):1345-52. 
 
Prodigiosin induces apoptosis by acting on mitochondria in human lung cancer cells.
Llagostera E, Soto-Cerrato V, Montaner B, Perez-Tomas R. 
Ann N Y Acad Sci. 2003 Dec;1010:178-81. 
 
The prodigiosins, proapoptotic drugs with anticancer properties.
Perez-Tomas R, Montaner B, Llagostera E, Soto-Cerrato V. 
Biochem Pharmacol. 2003 Oct 15;66(8):1447-52. Review.