As a model we use the gene encoding for Dihydrofolate reductase (DHFR), enzyme that it is widely used as the target for the chemotherapy that uses methotrexate.

This group is part of the Consolidated Group "Anticancer and Antiinflammatory Therapies" together with the Department of Physiology from the School of Pharmacy, University of Barcelona.
Our group forms part of the "Gene Therapy Network" and "Medical Chemistry" suported by the Generalitat of Catalonia
At the international level, we maintain a
stable collaboration with the Department
of Biological Sciences.(
Columbia
University) and Molecular
Neuro-Oncology (Rockefeller
University), both in New York City.