Research Interests

HEPATITIS A AND E VIRUSES

Molecular and antigenic characterisation.
Virus evolution.
Cellular cycle.
Molecular epidemiology.

GASTROENTERITIS VIRUSES

· Astroviruses.

Molecular and biological characterisation of protein nsP1a4.
Astrovirus morphogenesis.
Molecular epidemiology of astroviruses.

· Rotaviruses.
Molecular epidemiology of rotaviruses.

· Noroviruses.
Molecular epidemiology of caliciviruses.

ENVIROMENTAL VIROLOGY

Molecular environmental epidemiology of viruses in water and sewage.
Virus survival in the environment.
Virus disinfection.
Development of methodologies for the detection of viruses in environmental samples.

FOOD VIROLOGY

Development of standardised quantitative methodologies for the detection of viruses in food samples, in particular molluscan shellfish.
Development of methodologies to estimate infectious titers from physical genomesfor unculturable viruses.
Virus inactivation in food matrices.

VIROLOGICAL SAFETY OF DRUGS PURIFIED FROM HUMAN OR ANIMAL SOURCES

Virological determinations in viral safety validation studies.
Studies on the efficacy of antiviral agents. All procedures are performed in compliance with GLP standards.

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