Identified the key mechanistic aspects of the enzymes that trim carbohydrates attached to proteins

From left to right, the researchers Javier Iglesias-Fernández, Albert Ardèvol and Carme Rovira.
From left to right, the researchers Javier Iglesias-Fernández, Albert Ardèvol and Carme Rovira.
(05/10/2012)

Researchers from the Quantum Simulation of Biological Processes Research Group (), Department of Chemistry, University of Barcelona (UB) - located at the Barcelona Science Park (PCB) have identified important mechanistic aspects of the enzymes that trim carbohydrates attached to proteins. The study, done in collaboration with biochemical and structural biology groups from the UK, France and Australia, has been published in the current issue of  Angewandte Chemie i està classificat com a VIP (very important paper). Només el 5 % dels treballs editats en aquesta publicació reben aquesta distinció.

 
From left to right, the researchers Javier Iglesias-Fernández, Albert Ardèvol and Carme Rovira.
From left to right, the researchers Javier Iglesias-Fernández, Albert Ardèvol and Carme Rovira.
05/10/2012

Researchers from the Quantum Simulation of Biological Processes Research Group (), Department of Chemistry, University of Barcelona (UB) - located at the Barcelona Science Park (PCB) have identified important mechanistic aspects of the enzymes that trim carbohydrates attached to proteins. The study, done in collaboration with biochemical and structural biology groups from the UK, France and Australia, has been published in the current issue of  Angewandte Chemie i està classificat com a VIP (very important paper). Només el 5 % dels treballs editats en aquesta publicació reben aquesta distinció.

 

The work was directed by Carme Rovira, ICREA research professor at the UB, principal investigator of Quantum Simulation of Biological Processes  lʼQuantum Simulation of Biological Processes (IQTC) of the UB, and by Gideon Davies, Professor at University of York (UK). Researchers from the IQTC, Javier Iglesias-Fernández, a predoctorate student at SQPBIO and Albert Ardèvol, a former member of the group, also participated in the study. The simulations were carried out at the MareNostrum supercomputer of the Barcelona Supercomputing Center.

 
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