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We apply institutional economics and human capital perspectives to advance research on the influence of institutional factors predicting entrepreneurial growth aspirations. We use data that combines individual and country level information over the period 2006-13. The main findings suggest that some institutions represent a barrier to new ventures’ development (cost of property registration and fear of failure) while others may enhance it (access to credit and role models). Additionally, the role of entrepreneurs’ human capital appear to be moderated by the institutional context. We find that those entrepreneurs holding higher levels of human capital investment would attenuate their growth aspirations when regulation, access to credit, and fear of failure, will not be favorable. However, the influence of role models would strengthen that relationship.