{"id":20,"date":"2016-02-23T17:16:59","date_gmt":"2016-02-23T17:16:59","guid":{"rendered":"http:\/\/www.ub.edu\/cellbiology\/?page_id=20"},"modified":"2026-04-16T09:39:07","modified_gmt":"2026-04-16T09:39:07","slug":"publication","status":"publish","type":"page","link":"https:\/\/www.ub.edu\/cellbiology\/publication\/","title":{"rendered":"Publications"},"content":{"rendered":"<p><strong><span style=\"color: #e96656;\">Selected Publications<\/span><\/strong><\/p>\n<h4><em><strong><span style=\"color: #e96656;\">from the last years<\/span><\/strong><\/em><\/h4>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Ben\u00edtez-Garc\u00eda C, Mart\u00ednez-Garc\u00eda D, Kotev M, P\u00e9rez-Hern\u00e1ndez M, Westermaier Y, D\u00edaz L, Korrodi-Greg\u00f3rio L, Fontova P, Torres AA, P\u00e9rez-Tom\u00e1s R, Garc\u00eda-Valverde M, Quesada R, Soliva R, Soto-Cerrato V. <strong>Identification of the atypical antipsychotic Asenapine as a direct survivin inhibitor with anticancer properties and sensitizing effects to conventional therapies. <\/strong><em>Biomed Pharmacother, 2025.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Arias-Betancur A, Fontova P, Alonso-Carrillo D, Carreira-Barral I, Duis J, Garc\u00eda-Valverde M, Soto-Cerrato V, Quesada R, P\u00e9rez-Tom\u00e1s R. <strong>Deregulation of lactate permeability using a small-molecule transporter (Lactrans-1) disturbs intracellular pH and triggers cancer cell death. <\/strong><em>Biochem Pharmacol, 2024.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Alonso-Carrillo D, Arias-Betancur A, Carreira-Barral I, Fontova P, Soto-Cerrato V, Garc\u00eda-Valverde M, P\u00e9rez-Tom\u00e1s R, Quesada R. <strong>Small molecule anion carriers facilitate lactate transport in model liposomes and cells. <\/strong><em>iScience, 2023.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Espona-Fiedler M, Manuel-Manresa P, Ben\u00edtez-Garc\u00eda C, Fontova P, Quesada R, Soto-Cerrato V, P\u00e9rez-Tom\u00e1s R. <strong>Antimetastatic Properties of Prodigiosin and the BH3-Mimetic Obatoclax (GX15-070) in Melanoma. <\/strong><em>Pharmaceutics, 2023.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Molero-Valenzuela A, Fontova P, Alonso-Carrillo D, Carreira-Barral I, Torres AA, Garc\u00eda-Valverde M, Ben\u00edtez-Garc\u00eda C, P\u00e9rez-Tom\u00e1s R, Quesada R, Soto-Cerrato V. <strong>A Novel Late-Stage Autophagy Inhibitor That Efficiently Targets Lysosomes Inducing Potent Cytotoxic and Sensitizing Effects in Lung Cancer. <\/strong><em>Cancers, 2022.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>P\u00e9rez-Hern\u00e1ndez M, Cusc\u00f3 C, Ben\u00edtez-Garc\u00eda C, Bonelli J, Nuevo-Fonoll M, Soriano A, Mart\u00ednez-Garc\u00eda D, Arias-Betancur A, Garc\u00eda-Valverde M, Segura MF, Quesada R, Rocas J, Soto-Cerrato V, P\u00e9rez-Tom\u00e1s R. <strong>Multi-Smart and Scalable Bioligands-Free Nanomedical Platform for Intratumorally Targeted Tambjamine Delivery, a Difficult to Administrate Highly Cytotoxic Drug. <\/strong><em>Biomedicines, 2021.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle; text-align: justify;\">\n<li>Carreira-Barral I, Mielczarek M, Alonso-Carrillo D, Capurro V, Soto-Cerrato V, Perez Tomas R, Caci E, Garc\u0131a-Valverde M, Quesada R. <strong>Click-tambjamines as efficient and tunable bioactive anion transporters. <\/strong><em>ChemComm, 2020.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>P\u00e9rez-Hern\u00e1ndez M, Arias A, Mart\u00ednez-Garc\u00eda D, P\u00e9rez-Tom\u00e1s R, Quesada R, Soto-Cerrato V.<strong> Targeting autophagy for cancer treatment and tumor chemosensitization.<\/strong> <em>Cancers, 2019.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Mart\u00ednez-Garc\u00eda D, P\u00e9rez-Hern\u00e1ndez M, Korrodi-Greg\u00f3rio L, Quesada R, Ramos R, Baixeras N, P\u00e9rez-Tom\u00e1s R, Soto-Cerrato V. <strong>The natural-based antitumor compound T21 decreases survivin levels through potent STAT3 inhibition in lung cancer models.<\/strong> <em>Biomolecules, 2019.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Mart\u00ednez-Garc\u00eda D, Manero-Rup\u00e9rez N, Quesada R, Korrodi-Greg\u00f3rio L,\u00a0Soto-Cerrato\u00a0V.\u00a0<strong>Therapeutic strategies involving survivin inhibition in cancer.<\/strong> <em>Med Res Rev, 2018.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Hernando E, Capurro V, Cossu C, Fiore M, Garc\u00eda-Valverde M,\u00a0Soto-Cerrato\u00a0V, P\u00e9rez-Tom\u00e1s R, Moran O, Zegarra-Moran O, Quesada R.\u00a0<strong>Small molecule anionophores promote transmembrane anion permeation matching CFTR activity.<\/strong> <em>Sci Rep, 2018.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li><span lang=\"EN-US\">Jowett LA, Howe ENW,\u00a0Soto-Cerrato\u00a0V, Van Rossom W, P\u00e9rez-Tom\u00e1s R, Gale PA. <b>Indole-based perenosins as highly potent HCl transporters and potential anti-cancer agents<\/b>. <i>Sci Rep,<\/i><em> 2017.\u00a0<\/em><\/span><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li><span lang=\"EN-US\">Kotev M, Manuel-Manresa P, Hernando E,\u00a0Soto-Cerrato\u00a0V, Orozco M, Quesada R, P\u00e9rez-Tom\u00e1s R, Guallar V. <b>Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs<\/b>. <i>J Chem Inf Model,<\/i> <em>2017.<\/em><\/span><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Manuel-Manresa P, Korrodi-Greg\u00f3rio L, Hernando E, Villanueva A, Mart\u00ednez-Garc\u00eda D, Rodilla AM, Ramos R, Fardilha M, Moya J, Quesada R, Soto-Cerrato V, P\u00e9rez-Tom\u00e1s R. <strong>Novel Indole-based Tambjamine-Analogues Induce Apoptotic Lung Cancer Cell Death through p38 Mitogen-Activated Protein Kinase Activation<\/strong>. <em>Mol Cancer Ther,<\/em> <em>2017.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Rodilla AM, Korrodi-Greg\u00f3rio L, Hernando E, Manuel-Manresa P, Quesada R, P\u00e9rez-Tom\u00e1s R, Soto-Cerrato V. <strong>Synthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and cell death in lung cancer<\/strong>.\u00a0<em>Biochemical Pharmacology,<\/em> <em>2017.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Korrodi-Greg\u00f3rio L, Soto-Cerrato V, Vitorino R, Fardilha M, P\u00e9rez-Tom\u00e1s R. <strong>From Proteomic Analysis to Potential Therapeutic Targets: Functional Profile of Two Lung Cancer Cell Lines, A549 and SW900, Widely Studied in Pre-Clinical Research<\/strong>. <em>PLoS One, 2016.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Wu X, Judd LW, Howe ENW, Withecombe AM, Soto-Cerrato V, Li H, Busschaert N, Valkenier H, P\u00e9rez-Tom\u00e1s R, Sheppard DN, Jiang Y, Davis AP, and Gale PA.\u00a0<strong>Nonprotonophoric \u00a0electrogenic Cl\u2212 transport mediated by valinomycin-like carriers<\/strong>. <em>Chem,<\/em> <em>2016.<\/em><\/li>\n<\/ul>\n<ul style=\"list-style-type: circle;\">\n<li>Soto-Cerrato V, Manuel-Manresa P, Hernando E, Calabuig-Farinas S, Martinez-Romero A, Fernandez-Duenas V, Sahlholm K, Knopfel T, Garcia-Valverde M, Rodilla AM, Jantus-Lewintre E, Farr\u00e0s R, Ciruela F, P\u00e9rez-Tom\u00e1s R, Quesada R. <strong>Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells<\/strong>. <em>J Am Chem Soc, 2015.<\/em><\/li>\n<\/ul>\n<p>To view all publications by each researcher:<\/p>\n<p>ORCID ID Ricardo P\u00e9rez-Tom\u00e1s: <a href=\"http:\/\/orcid.org\/0000-0003-3226-1240\">0000-0003-3226-1240<\/a><\/p>\n<p>ORCID ID Vanessa Soto-Cerrato:<a href=\"http:\/\/orcid.org\/0000-0001-5835-3595\"> 0000-0001-5835-3595<\/a><\/p>\n<p>ORCID ID Laura Devis-Jauregui: <a href=\"https:\/\/orcid.org\/0000-0003-3736-3983\">0000-0003-3736-3983<\/a><\/p>\n<p>ORCID ID Pere Fontova: <a href=\"https:\/\/orcid.org\/0000-0002-1352-3084\">0000-0002-1352-3084<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Selected Publications from the last years Ben\u00edtez-Garc\u00eda C, Mart\u00ednez-Garc\u00eda D, Kotev M, P\u00e9rez-Hern\u00e1ndez M, Westermaier Y, D\u00edaz L, Korrodi-Greg\u00f3rio L, Fontova P, Torres AA, P\u00e9rez-Tom\u00e1s R, Garc\u00eda-Valverde M, Quesada R, Soliva R, Soto-Cerrato V. Identification of the atypical antipsychotic Asenapine as a direct survivin inhibitor with anticancer properties and sensitizing effects to conventional therapies. Biomed<a href=\"https:\/\/www.ub.edu\/cellbiology\/publication\/\">[&#8230;]<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":40,"comment_status":"closed","ping_status":"closed","template":"template-fullwidth.php","meta":{"footnotes":""},"class_list":["post-20","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/pages\/20","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/comments?post=20"}],"version-history":[{"count":35,"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/pages\/20\/revisions"}],"predecessor-version":[{"id":1141,"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/pages\/20\/revisions\/1141"}],"wp:attachment":[{"href":"https:\/\/www.ub.edu\/cellbiology\/wp-json\/wp\/v2\/media?parent=20"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}