Drugs from Drugs

Discovery of new bioactive agents by modification of known drugs using Multicomponent Reactions. Facilitated Access to Libraries of

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Proapoptotic TrifluoroThiazoles

Direct synthetic access to compounds in 1-2 steps, to trigger Proapoptotic p-53 independent antitumoral activity, and Sdelectively targeting prohibitins (Collaboration…

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This constitutes a new research line initiated by Dr. Christian Griñán-Ferré, by using C. elegans, as well as several mice models…

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