Publications

Design, synthesis, and multitarget biological profiling of second generation anti-Alzheimer rhein-huprine hybrids

Pérez-Areales, F. J.; Betari, N.; Viayna, A.; Pont, C.; Espargaró, A.; Bartolini, M.; De Simone, A.; Rinaldi Alvarenga, J. F.; Pérez, B.; Sabate, R.; Lamuela-Raventós, R. M.; Andrisano, V.; Luque, F. J.; Muñoz-Torrero, D.

Fut. Med. Chem. 2017, 9, 965-981.

Selected Publications

The protein aggregation inhibitor YAT2150 has potent antimalarial activity in Plasmodium falciparum in vitro cultures

Bouzón-Arnáiz, I.; Avalos-Padilla, Y.; Biosca, A.; Caño-Prades, O.; Román-Álamo, L.; Valle, J.; Andreu, D.; Moita, D.; Prudêncio, M.; Arce, E.…

Unveiling the multitarget anti-Alzheimer drug discovery landscape: A bibliometric analysis

Sampietro, A.; Pérez-Areales, F. J.; Martínez, P.; Arce, E. M.; Galdeano, C.; Muñoz-Torrero, D. Pharmaceuticals 2022, 15, 545

Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimer’s disease

Codony, S.; Pont, C.; Griñán-Ferré, C.; Di Pede-Mattatelli, A.; Calvó-Tusell, C.; Feixas, F.; Osuna, S.; Jarné-Ferrer, J.; Naldi, M.; Bartolini,…

From virtual screening hits targeting a cryptic pocket in BACE-1 to a nontoxic brain permeable multitarget anti-Alzheimer lead with disease-modifying and cognition-enhancing effects

Pont, C.; Ginex, T.; Griñán-Ferré, C.; Scheiner, M.; Mattellone, A.; Martínez, N.; Arce, E. M.; Soriano-Fernández, Y.; Naldi, M.; De…