Discovery and in vivo proof of concept of a highly potent dual inhibitor of soluble epoxide hydrolase and acetylcholinesterase for the treatment of Alzheimer’s disease

Overexpression in Plasmodium falciparum of an intrinsically disordered segment of PfUT impairs the parasite’s proteostasis and reduces its growth rate

Ávalos-Padilla, Y.; Bouzón-Arnáiz, I.; Ramírez, M.; Camarero-Hoyos, C.; Orozco-Quer, M.; Arce, E.M.; Muñoz-Torrero, D.; Fernàndez-Busquets, X. Front. Cell. Infect. Microbiol.…

Combining the zebrafish embryo developmental toxicity assay (ZEDTA) with hemoglobin staining to accelerate the research of novel antimalarial drugs for pregnant women

Borrallo-Lopez, L.; Guzman, L.; Romero, N.G.; Sampietro, A.; Mallo-Abreu, A.; Guardia-Escote, L.; Teixidó, E.; Flick, B.; Fernàndez-Busquets, X.; Muñoz-Torrero, D.;…

Proteome aggregation in cells derived from amyotrophic lateral sclerosis patients for personalized drug evaluation

Pérez de la Lastra Aranda, C.; Tosat-Bitrián, C.; Porras, G.; Dafinca, R.; Muñoz-Torrero, D.; Talbot, K.; Martín-Requero, Á.; Martínez, A.;…

Leveraging the aggregated protein dye YAT2150 for malaria chemotherapy

Camarero-Hoyos, C.; Bouzón-Arnáiz, I.; Avalos-Padilla, Y.; Fallica, A.N.; Román-Álamo, L.; Ramírez, M.; Portabella, E.; Cuspinera, O.; Currea-Ayala, D.; Orozco-Quer, M.;…

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