Fluorogenic Trp(redBODIPY) Cyclopeptide Targeting Keratin 1 for Imaging of Aggressive Carcinomas.

Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants

Synopsis We describe diazonium BODIPYs for the straightforward labeling of Tyr-containing peptides and whole proteins and the first fluorogenic analogue…

Reaction Space Charting as a Tool in Organic Chemistry Research and Development

Eloy Lozano Baró, Pau Nadal Rodríguez, Jordi Juárez-Jiménez, Ouldouz Ghashghaei*, Rodolfo Lavilla* https://doi.org/10.1002/adsc.202301205 The chemical and reaction spaces are incredibly…

The Prohibitin-Binding Compound Fluorizoline Induces the Pro-inflammatory Cytokines Interleukin-8 and Interleukin-6 through the Activation of JNK and p38 MAP Kinases

Ismael Sánchez-Vera, José Saura-Esteller, Sonia Núñez-Vázquez, Ana M Cosialls, Ouldouz Ghashghaei, Rodolfo Lavilla, Gabriel Pons, Joan Gil, Daniel Iglesias-Serret DOI: 10.1016/j.bcp.2023.115860…

Charting the Chemical Reaction Space around a Multicomponent Combination: Controlled Access to a Diverse Set of Biologically Relevant Scaffolds

Pau Nadal Rodríguez, Ouldouz Ghashghaei*, Anna M. Schoepf, Sam Benson, Marc Vendrell, Rodolfo Lavilla* https://doi.org/10.1002/ange.202303889 Charting the chemical reaction space…

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