Diagnostics with Modern Chemical Probes
Generation of functional probes by modern chemistry such as CH activation for modified tryptophan peptides and the preparation of fluorescent…
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Neurodegeneration in ageing and neurodegenerative diseases
We focus our research in the study of the molecular mechanisms involved in behavioral abnormalities and cognitive decline, by using…
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Design, synthesis and evaluation of new polycyclic inhibitors of the M2 channel of the influenza A virus.
Amantadine and rimantadine have been in clinical use as anti-influenza A virus agents for decades. The mechanism of action of…
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New imidazoline I2 receptor ligands
The imidazoline I2 receptors (I2-IRs) are altered in the brain of Alzheimer’s disease patients and I2-IR ligands may have therapeutic…
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