Diagnostics with Modern Chemical Probes

Generation of functional probes by modern chemistry such as CH activation for modified tryptophan peptides and the preparation of fluorescent isocyanides for multicomponent reactions. (Collaboration M. Vendrell, U. Edinburgh)

Diagnostics with Modern Chemical Probes

Generation of functional probes by modern chemistry such as CH activation for modified tryptophan peptides and the preparation of fluorescent…

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Neurodegeneration in ageing and neurodegenerative diseases

  We focus our research in the study of the molecular mechanisms involved in behavioral abnormalities and cognitive decline, by using…

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Design, synthesis and evaluation of new polycyclic inhibitors of the M2 channel of the influenza A virus.

Amantadine and rimantadine have been in clinical use as anti-influenza A virus agents for decades. The mechanism of action of…

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New imidazoline I2 receptor ligands

The imidazoline I2 receptors (I2-IRs) are altered in the brain of Alzheimer’s disease patients and I2-IR ligands may have therapeutic…

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