University of Barcelona

Information for the student – Genetics and Genomics

Final project

What is a Master Thesis? The master’s thesis is a piece of original research work written under the direction of an experienced advisor. All students will undertake a Master’s Thesis or Trabajo Final de Master-TFM (30 ECTS). The Thesis is typically based on an experimental research project carried out in one of the research groups of the list shown in this page.Students may be interested in pursuing further research, for instance in a doctoral (PhD) program, or as a researcher in hospitals or research institutes. 

How to do a Master Thesis? You will learn how to plan a research project choose adequate methods to performing the experiments and analysing the results. You will write your Thesis as if it were a scientific publication, critically describing, contemplating and discussing your results in the light of previous scientific literature on the topic.In your written Thesis you are expected to demonstrate that you are capable of scientific thinking, that you are familiar with the methodology and with the topic of your research. The written Thesis is an important exercise for developing skills in project management and written scientific communication. 

Where to find the labs to do the Master Thesis? Below you will find a list of laboratories you can apply. You will see a brief title of the work, a link to the web page of the research group and the name of the supervisor. If you decide to join a particular group for your Master Thesis, write an email to the supervisor and ask for further information and availability. 

If you have problems finding a lab, please contact the master’s coordinator.

 

Select your laboratory for the research project (Master Thesis/TFM)

University of Barcelona 2023-24

University of Barcelona, School of Biology offers 2023-24

Viral metagenomics for pandemic species surveiilance and characterization

Transcriptomic landscape of planarian, a model organism in regeneration

Josep F. Abril

 

How to rejuvenate stem cells: the role of autophagy during starvation in regenerative processes

Teresa Adell i Cristina González-Estévez

 

Deciphering the molecular signature of planarian organizers: the key of being a whole-body regenerative animal

Teresa Adell

 

New organs in insects

Isabel Almudí

 

Genetics and cell biology of single-cell branching morphogenesis, implications for human disease

Sofia J. Araújo

 

How does a mutation in a single gene manage to cause a full intellectual disability- developmental delay syndrome?

Susanna Balcells Raquel Rabionet

 

Characterization of antimicrobial peptides (AMPs) in the newly sequenced genome of the endemic Balearic lizard Podarcis lilfordi and their role in shaping the gut microbiota symbiosis 

Laura Baldo

 

Gene loss and heart embryonic development in Oikopleura dioica

Development of new CRISPR tools in Oikopleura dioica

Cristian Cañestro & Alfonso Ferrández

 

Genomics and transcriptomics of embryo response to marine biotoxins in the context of climate change

Cristian Cañestro & Nuria Torres-Aguila

 

Transcriptomics of embryo response to anthropogenic noise contamination in the context of the European Deuteronoise consortium

Cristian Cañestro & Eva Rodríguez-Quintana

 

Medical genomics of primary immunodeficiencies

Ferran Casals

 

Exploring the genetic basis of psychiatric disorders in humans and animal models

Bru Cormand and Noelia Fernandez 

 

Generation and study of iPSC-derived neurons of patients with 7q11.23 rearrangements

Roser Corominas

 

Expression of transcription factors during epithelial regeneration

Montserrat Corominas

 

Early animal evolution using genome-scale data

Insect metamorphosis evolution

Jesus Lozano

 

Unexpected molecular encounters: How exogenous genes interact with new host genomes when they meet for the first time?

Ignacio Maeso

 

Gene therapy for Retitinis pigmentosa: a preclinical assay using adenoassociated viruses (AAVs) in the CerklKD/KO mouse model *

Gemma Marfany and Serena Mirra

 

Computational genomics of the special amino acid selenocysteine

Marco Mariotti

 

Neural plastcity during organ remodeling

Marta Morey

 

Function of CBP/p300 homologues on neoblast cell cylce progression and progenitor specification during planarian regeneration

Loli Molina i Francesc Cebrià

 

Effect of VNN2 variants in neutrophil transmigration and the stroke recovery process? *

Raquel Rabionet

 

Comparative and evolutionary analysis of multi-gene families in spider genomes

Julio Rozas

 

Climate change genomics: the genomics basis of rapid adaptation in natural populations

Alejandro Sanchez

 

CRISPR-Cas9 Screening of RNA Modifying enzymes in Pluripotent Stem Cells*

Ana Sevilla

 

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University of Barcelona, School of Medicine offers 2023-24

Genetic and epigenetic signatures modulating liver and adipose tissue crosstalk in NAFLD

Pablo M Garcia-Roves

 

Immunogenic activity of non-coding RNAs in Huntington’s disease

Eulàlia Martí

 

* indicates group has already accepted one student (some groups may accept more than one student)

Centre for Genomic Regulation (CRG)

 

Elucidating the tissue-specific regulatory logic of Srrm3 and Srrm4 in vertebrates

Multi-layer transcriptomic analysis of the evolution of tissue-specific gene regulation

Understanding the impact of microexon mis-regulation in zebrafish sleep/wake behaviors

Manu Irimia

 

Epigenetic regulation of mammalian germ cell development

Bernhard Payer

 

Mechanobiology in development and multicellular self-organisation

Verena Ruprecht

 

Investigating animal cell type diversity, evolution and regulation using single cell genomics and epigenomics approaches

Arnau Sebé

 

Efficient computational gene identification across the tree of life

Roderic Guigó

 

Origin and evolution of novel mammalian genes

Roderic Guigó and Harris Lewin

 

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Centre Nacional d'Anàlisi Genòmica (CNAG)

 

Diagnosis and stratification of neuroblastoma samples from circulating tumour DNA (bioinformatics project, background in Python/R required)

Simon Heath

 

Allele specific methylation in cancer/normal pairs (bioinformatics project, background in Python/R required)

Emanuele Raineri

 

Use of novel reference genomes to improve variant discovery in African patients with rare diseases

Pedro Rodriguez

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European Molecular Biology Lab (EMBL- Barcelona)

 

A stem cell zoo platform to uncover intracellular scaling of developmental tempo across mammals

Jorge Lázaro and Miki Ebisuya

 

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Bellvitge Biomedical Research Institute (IDIBELL)

 

Dynamics of stem cell surveillance in live embryos using quantitative imaging

Esteban Hoijman

 

Identification of new prognostic and diagnostic markers for urogenital diseases based on ncRNAs in biofluids

Sara Larriba

 

Analyzing the missing heritability of different hereditary cancer conditions / Deepening the classification of genetic variants in genes related to cancer predisposition

Conxi Lázaro

 

Organoids for diabetes treatment

Meritxell Rovira

 

Functional characterization of hereditary cancer genes

Laura Valle

 

CRISPR-Cas in C. elegans to optimize genome-editing in animals and to model human diseases

Julian Ceron

 

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Germans Trias i Pujol Research Institute (IGTP), Can Ruti, Badalona

 

Deciphering the role of HDAC11 in muscular dystrophies

Monica Suelves

 

Using genomes for life to understand the prevalence of repeat expansion disorders

Gisela Nogales-Gadea

 

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Hospital Sant Joan de Déu - Fundació Sant Joan de Déu

 

Identifying novel therapeutic vulnerabilities in pediatric cancer

Alexandra Avgustinova

 

Therapeutic target validation study in a sample of patients with Rett syndrome: detection of the molecular signature of neurodevelopmental disorders

Delia Yubero &  Judith Armstrong

 

Study of the molecular bases of neurodevelopmental diseases to define personalized treatments

Alfonso Oyarzabal

 

Non-genomic Inheritance of environmentally-induced traits: Deciphering epigenetically-driven genetic variation in mammals 

Josep C Jimenez-Chillaron

 

Closing the therapeutic gap for congenital muscular dystrophies: improving efficacy, delivery and safety of CRISPR/cas9 and antisense oligonucleotides based therapies

Arístides López-Márquez and Cecilia Jiménez Mallebrera

 

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Hospital Clínic de Barcelona

 

Whole genome sequencing applied to neurodevelopmental disorder patients

Maria Isabel Alvarez

 

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Institut Botànic de Barcelona (IBB-CSIC)

 

Comparative and population genomics of migratory butterflies

Gerard Talavera

 

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Institut de Biologia Molecular de Barcelona (IBMB-CSIC-PCB)

 

Modeling neurodevelopmental disorders in the mouse and 3D organoids

Maria Lourdes Arbonés

 

Molecular Basis of cellular drug persistence: from stochastic gene expression to phase transitions

Hector Garcia-Seisdedos

 

From Drosophila development to human disease

Gerardo Jiménez

 

Occupancy of histone H1 variants genome-wide and consequences of altering H1 levels on human chromatin organization and gene expression

Albert Jordan

 

The role of the extracellular matrix in the condensation of the nervous system of the Drosophila embryo

Katerina Karkali & Enrique Martín-Blanco

 

Cellular and molecular mechanisms regulating epithelial morphogenesis in Drosophila

Marta Llimargas Casanova

 

Building human spinal cord organoids to study human specific developmental features and neurodevelompental disorders

Elisa Martí

 

Understanding epigenetic mechanisms involved in early neurogenesis and neurodevelopmental disorders 

Marian Martinez-Balbas

 

Communication between the mitochondrial and nuclear genomes in humans

Genetics of developmental rate in the model organism Caenorhabditis elegans

Marcos Francisco Perez

 

The Contribution of Human-Acquired Centrosome-Cilia Genes in Normal and Pathological Neural Development

Murielle Saade

 

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IDIBAPS

 

Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer

Antonio Postigo

 

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Institute of Biomedical Research (IRB)

Drosophila, a model to understand development, regeneration and cancer *

Marco Milán

 

Survival mechanisms and plasticity of Drosophila adult progenitor cells

Jordi Casanova

 

Functional study of pediatric oncogenes in Drosophila

Cayetano Gonzalez

 

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Institute of Environmental Assessment and Water Research (IDAEA-CSIC)

Identification of biomarkers of exposures to environmental pollutans in zebrafish using a multi-omics approach 

Characterization of epigenetic induced modifications by endocrine disruptors in zebrafish 

Laia Navarro-Martín

 

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Institue of Evolutionary Biology (IBE) (CSIC - Universitat Pompeu Fabra)

 

Exploring the genomic basis of terrestrialization across animals through comparative genomics

Rosa Fernández

 

Role and regulation of temporal specifiers during insect development 

Xavier Franch-Marro & David Martín

 

Genomics of adaptation to urban and natural environments in Anopheles and Drosophila

Josefa González

 

The affair of the insect insulin receptors

José Luis Maestro

 

Small RNAs regulating insect oogenesis

M. Dolors Piulachs

 

The unknown cell biology and genomics of the most abundant marine microbial eukaryotes

Daniel J. Richter

 

Unraveling the cell biology of the closest relatives of animals

Iñaki Ruiz & Elena Casacuberta 

 

Single-cell microbial ecology of the coral holobiont under heat stress

Structure and Evolution of Coral-Photosymbiont Networks , shared with Sergi Valverde lab

Javier del Campo

 

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Institut Hospital del Mar d'Investigació Mèdica (IMIM)

 

Evaluation of HIV-induced inflammation measuring inflammatory biomarkers, and evaluation of cardiovascular tissue inflammation

Natalia Garcia Giralt

 

Deciphering Intercellular Communication in Cancer and Ageing-related Diseases

Patrick-Simon Welz

 

Implementation of Optical Genome Mapping technology as a tool new cytogenomic tool for diagnosis and research in hematologic malignancies

Blanca Espinet Sola

 

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Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC)

 

Dorso-ventral limb patterning and its implication in morphogenesis, evolution and disease

Marian Ros

 

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Josep Carreras Leukaemia Research Institute (IJC)

 

Epigenetic and metabolic functions of histone variants

Marcus Buschbeck

 

Studying the function of regulatory RNAs in neurodevelopmental diseases

Sonia Guil

 

Epigenetic dysregulation and immune cell crosstalk in inflammation

Esteban Ballestar

 

Impact of the dual catalytic activities of the aging-related sirtuin family members in cancer progression.

Irene Fernández-Duran Alejandro Vaquero

 

Improve mechanistic understanding of Pediatric B-cell precursor Acute Lymphoblastic Leukemia to find new biomarkers and therapeutic approaches

Biola M. Javierre

 

Epigenetics of Human Cancer: DNA Methylation, Histone Modifications and Non-Coding RNAs

Manel Esteller i Verónica Padial

 

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Institut de Salut Global Barcelona (ISGlobal)

 

Regulation of gene expression in malaria parasites

Alfred Cortés

 

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Universitat Pompeu Fabra (UPF)

Analysis of the diversity of the human genome: demography and adaptation

David Comas

 

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Universitat Internacional de Catalunya (UIC)

 

Advances in diagnostic and therapy for rare hereditary haematological diseases (ARETHA Project)

Mayka Sánchez

 

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Vall d'Hebron Institut de Recerca (VHIR)

 

Shared genetic architecture between inflammatory processes and depression: exploring genetic correlations, overlap and causality

Silvia Alemany &Maria Soler-Artigas

 

Impact of Neurodevelopmental Disorders on School Performance in 6,000 school-age children: genes and environment

Marta Ribasés & Judit Cabana

 

Retrospective exome reanalysis through literature search of new disease-associated genes *

Núria Martínez-Gil & Marta Codina

 

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* indicates group has already accepted one student (some groups may accept more than one student)

The internatinal relationship office (ORI) at Biologia offers the possibility to apply for an ERASMUS Fellowship to do your TFM abroad. in this website you can check for mor info, or contact ori-bio@ub.edu.

International (ERASMUS) placements

 

Optogenetics and Chemical genetics tool development to study heart development in a simple marine chordate

International Center for Marine Molecular Biology (BERGEN)

Lionel Christiaen

 

RNA degradation by the exosome and its contribution to chromatin regulation and genome integrity

Department of Molecular Biosciences, The Wenner-Gren Institute (MBW), Stockholm University, Stockholm, Sweden

Neus Visa

 

Crosstalks between transcription, replication and genome stability

Institut de Génétique Moléculaire de Montpellier (IGMM)

Domenico Libri

 

Molecular basis of juvenile amyotrophic lateral sclerosis

Institut de Génétique Moléculaire de Montpellier (IGMM)

Odil Porrua

 

Early embryo development

Centre for Regenerative Medicine, Institute for Stem Cell Research, The University of Edinburgh.

Anahi Binagui (Valerie Wilson's Lab)

 

Enhancer dissection at disease-associated loci with CRISPR and base editing

St. Anna Kinderkrebsforschung (Children's cancer research institute)

Davide Seruggia

 

Does regeneration re-use developmental gene regulatory networks?

IGFL Lyon, France

Mathilde Paris

 

Multi-omics characterization of skeletal muscle in health and disease

IGBMC Strasbourg, France

Alix Simon and Jocelyn Laporte

 

Pathomechanism and treatment of neuromuscular diseases

IGBMC Strasbourg, France

Jocelyn Laporte

 

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