University of Barcelona

Information for the student – Genetics and Genomics

Master Thesis/TFM

What is a Master Thesis? The master’s thesis is a piece of original research work written under the direction of an experienced advisor. All students will undertake a Master’s Thesis or Trabajo Final de Master-TFM (30 ECTS). The Thesis is typically based on an experimental research project carried out in one of the research groups of the list shown in this page.Students may be interested in pursuing further research, for instance in a doctoral (PhD) program, or as a researcher in hospitals or research institutes. 

How to do a Master Thesis? You will learn how to plan a research project choose adequate methods to performing the experiments and analysing the results. You will write your Thesis as if it were a scientific publication, critically describing, contemplating and discussing your results in the light of previous scientific literature on the topic.In your written Thesis you are expected to demonstrate that you are capable of scientific thinking, that you are familiar with the methodology and with the topic of your research. The written Thesis is an important exercise for developing skills in project management and written scientific communication. 

Where to find the labs to do the Master Thesis? Below you will find a list of laboratories you can apply. You will see a brief title of the work, a link to the web page of the research group and the name of the supervisor. If you decide to join a particular group for your Master Thesis, write an email to the supervisor and ask for further information and availability. 

If you have problems finding a lab, please contact the master’s coordinator.


Select your laboratory for the research project (Master Thesis/TFM)

University of Barcelona 2023-24

University of Barcelona, School of Biology offers 2023-24

Viral metagenomics for pandemic species surveiilance and characterization

Transcriptomic landscape of planarian, a model organism in regeneration

Josep F. Abril


How to rejuvenate stem cells: the role of autophagy during starvation in regenerative processes

Teresa Adell i Cristina González-Estévez


Deciphering the molecular signature of planarian organizers: the key of being a whole-body regenerative animal

Teresa Adell


New organs in insects

Isabel Almudí


Genetics and cell biology of single-cell branching morphogenesis, implications for human disease

Sofia J. Araújo


How does a mutation in a single gene manage to cause a full intellectual disability- developmental delay syndrome?

Susanna Balcells Raquel Rabionet


Characterization of antimicrobial peptides (AMPs) in the newly sequenced genome of the endemic Balearic lizard Podarcis lilfordi and their role in shaping the gut microbiota symbiosis 

Laura Baldo


Gene loss and heart embryonic development in Oikopleura dioica

Development of new CRISPR tools in Oikopleura dioica

Cristian Cañestro & Alfonso Ferrández


Genomics and transcriptomics of embryo response to marine biotoxins in the context of climate change

Cristian Cañestro & Nuria Torres-Aguila


Transcriptomics of embryo response to anthropogenic noise contamination in the context of the European Deuteronoise consortium

Cristian Cañestro & Eva Rodríguez-Quintana


Medical genomics of primary immunodeficiencies

Ferran Casals


Exploring the genetic basis of psychiatric disorders in humans and animal models

Bru Cormand and Noelia Fernandez 


Generation and study of iPSC-derived neurons of patients with 7q11.23 rearrangements

Roser Corominas


Expression of transcription factors during epithelial regeneration

Montserrat Corominas


Early animal evolution using genome-scale data

Insect metamorphosis evolution

Jesus Lozano


Unexpected molecular encounters: How exogenous genes interact with new host genomes when they meet for the first time?

Ignacio Maeso


Gene therapy for Retitinis pigmentosa: a preclinical assay using adenoassociated viruses (AAVs) in the CerklKD/KO mouse model *

Gemma Marfany and Serena Mirra


Computational genomics of the special amino acid selenocysteine

Marco Mariotti


Neural plastcity during organ remodeling

Marta Morey


Function of CBP/p300 homologues on neoblast cell cylce progression and progenitor specification during planarian regeneration

Loli Molina i Francesc Cebrià


Effect of VNN2 variants in neutrophil transmigration and the stroke recovery process? *

Raquel Rabionet


Comparative and evolutionary analysis of multi-gene families in spider genomes

Julio Rozas


Climate change genomics: the genomics basis of rapid adaptation in natural populations

Alejandro Sanchez


CRISPR-Cas9 Screening of RNA Modifying enzymes in Pluripotent Stem Cells*

Ana Sevilla



University of Barcelona, School of Medicine offers 2023-24

Genetic and epigenetic signatures modulating liver and adipose tissue crosstalk in NAFLD

Pablo M Garcia-Roves


Immunogenic activity of non-coding RNAs in Huntington’s disease

Eulàlia Martí


* indicates group has already accepted one student (some groups may accept more than one student)

Centre for Genomic Regulation (CRG)


Elucidating the tissue-specific regulatory logic of Srrm3 and Srrm4 in vertebrates

Multi-layer transcriptomic analysis of the evolution of tissue-specific gene regulation

Understanding the impact of microexon mis-regulation in zebrafish sleep/wake behaviors

Manu Irimia


Epigenetic regulation of mammalian germ cell development

Bernhard Payer


Mechanobiology in development and multicellular self-organisation

Verena Ruprecht


Investigating animal cell type diversity, evolution and regulation using single cell genomics and epigenomics approaches

Arnau Sebé


Efficient computational gene identification across the tree of life

Roderic Guigó


Origin and evolution of novel mammalian genes

Roderic Guigó and Harris Lewin



Centre Nacional d'Anàlisi Genòmica (CNAG)


Diagnosis and stratification of neuroblastoma samples from circulating tumour DNA (bioinformatics project, background in Python/R required)

Simon Heath


Allele specific methylation in cancer/normal pairs (bioinformatics project, background in Python/R required)

Emanuele Raineri


Use of novel reference genomes to improve variant discovery in African patients with rare diseases

Pedro Rodriguez



European Molecular Biology Lab (EMBL- Barcelona)


A stem cell zoo platform to uncover intracellular scaling of developmental tempo across mammals

Jorge Lázaro and Miki Ebisuya




Implementation of a liquid biopsy-based integral strategy for monitoring pediatric sarcomas

Jairo Rodriguez


Bellvitge Biomedical Research Institute (IDIBELL)


Dynamics of stem cell surveillance in live embryos using quantitative imaging

Esteban Hoijman


Identification of new prognostic and diagnostic markers for urogenital diseases based on ncRNAs in biofluids

Sara Larriba


Analyzing the missing heritability of different hereditary cancer conditions / Deepening the classification of genetic variants in genes related to cancer predisposition

Conxi Lázaro


Organoids for diabetes treatment

Meritxell Rovira


Functional characterization of hereditary cancer genes

Laura Valle


CRISPR-Cas in C. elegans to optimize genome-editing in animals and to model human diseases

Julian Ceron



Germans Trias i Pujol Research Institute (IGTP), Can Ruti, Badalona


Deciphering the role of HDAC11 in muscular dystrophies

Monica Suelves


Using genomes for life to understand the prevalence of repeat expansion disorders

Gisela Nogales-Gadea



Hospital Sant Joan de Déu - Fundació Sant Joan de Déu


Identifying novel therapeutic vulnerabilities in pediatric cancer

Alexandra Avgustinova


Therapeutic target validation study in a sample of patients with Rett syndrome: detection of the molecular signature of neurodevelopmental disorders

Delia Yubero &  Judith Armstrong


Study of the molecular bases of neurodevelopmental diseases to define personalized treatments

Alfonso Oyarzabal


Non-genomic Inheritance of environmentally-induced traits: Deciphering epigenetically-driven genetic variation in mammals 

Josep C Jimenez-Chillaron


Closing the therapeutic gap for congenital muscular dystrophies: improving efficacy, delivery and safety of CRISPR/cas9 and antisense oligonucleotides based therapies

Arístides López-Márquez and Cecilia Jiménez Mallebrera



Hospital Clínic de Barcelona


Whole genome sequencing applied to neurodevelopmental disorder patients

Maria Isabel Alvarez



Institut Botànic de Barcelona (IBB-CSIC)


Comparative and population genomics of migratory butterflies

Gerard Talavera



Institut de Biologia Molecular de Barcelona (IBMB-CSIC-PCB)


Modeling neurodevelopmental disorders in the mouse and 3D organoids

Maria Lourdes Arbonés


Molecular Basis of cellular drug persistence: from stochastic gene expression to phase transitions

Hector Garcia-Seisdedos


From Drosophila development to human disease

Gerardo Jiménez


Occupancy of histone H1 variants genome-wide and consequences of altering H1 levels on human chromatin organization and gene expression

Albert Jordan


The role of the extracellular matrix in the condensation of the nervous system of the Drosophila embryo

Katerina Karkali & Enrique Martín-Blanco


Cellular and molecular mechanisms regulating epithelial morphogenesis in Drosophila

Marta Llimargas Casanova


Building human spinal cord organoids to study human specific developmental features and neurodevelompental disorders

Elisa Martí


Understanding epigenetic mechanisms involved in early neurogenesis and neurodevelopmental disorders 

Marian Martinez-Balbas


Communication between the mitochondrial and nuclear genomes in humans

Genetics of developmental rate in the model organism Caenorhabditis elegans

Marcos Francisco Perez


The Contribution of Human-Acquired Centrosome-Cilia Genes in Normal and Pathological Neural Development

Murielle Saade





Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer

Antonio Postigo



Institute of Biomedical Research (IRB)

Drosophila, a model to understand development, regeneration and cancer *

Marco Milán


Survival mechanisms and plasticity of Drosophila adult progenitor cells

Jordi Casanova


Functional study of pediatric oncogenes in Drosophila

Cayetano Gonzalez



Institute of Environmental Assessment and Water Research (IDAEA-CSIC)

Identification of biomarkers of exposures to environmental pollutans in zebrafish using a multi-omics approach 

Characterization of epigenetic induced modifications by endocrine disruptors in zebrafish 

Laia Navarro-Martín



Institue of Evolutionary Biology (IBE) (CSIC - Universitat Pompeu Fabra)


Exploring the genomic basis of terrestrialization across animals through comparative genomics

Rosa Fernández


Role and regulation of temporal specifiers during insect development 

Xavier Franch-Marro & David Martín


Genomics of adaptation to urban and natural environments in Anopheles and Drosophila

Josefa González


The affair of the insect insulin receptors

José Luis Maestro


Small RNAs regulating insect oogenesis

M. Dolors Piulachs


The unknown cell biology and genomics of the most abundant marine microbial eukaryotes

Daniel J. Richter


Unraveling the cell biology of the closest relatives of animals

Iñaki Ruiz & Elena Casacuberta 


Single-cell microbial ecology of the coral holobiont under heat stress

Structure and Evolution of Coral-Photosymbiont Networks , shared with Sergi Valverde lab

Javier del Campo



Institut Hospital del Mar d'Investigació Mèdica (IMIM)


Evaluation of HIV-induced inflammation measuring inflammatory biomarkers, and evaluation of cardiovascular tissue inflammation

Natalia Garcia Giralt


Deciphering Intercellular Communication in Cancer and Ageing-related Diseases

Patrick-Simon Welz


Implementation of Optical Genome Mapping technology as a tool new cytogenomic tool for diagnosis and research in hematologic malignancies

Blanca Espinet Sola



Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC)


Dorso-ventral limb patterning and its implication in morphogenesis, evolution and disease

Marian Ros



Josep Carreras Leukaemia Research Institute (IJC)


Epigenetic and metabolic functions of histone variants

Marcus Buschbeck


Studying the function of regulatory RNAs in neurodevelopmental diseases

Sonia Guil


Epigenetic dysregulation and immune cell crosstalk in inflammation

Esteban Ballestar


Impact of the dual catalytic activities of the aging-related sirtuin family members in cancer progression.

Irene Fernández-Duran Alejandro Vaquero


Improve mechanistic understanding of Pediatric B-cell precursor Acute Lymphoblastic Leukemia to find new biomarkers and therapeutic approaches

Biola M. Javierre


Epigenetics of Human Cancer: DNA Methylation, Histone Modifications and Non-Coding RNAs

Manel Esteller i Verónica Padial



Institut de Salut Global Barcelona (ISGlobal)


Regulation of gene expression in malaria parasites

Alfred Cortés



Universitat Pompeu Fabra (UPF)

Analysis of the diversity of the human genome: demography and adaptation

David Comas



Universitat Internacional de Catalunya (UIC)


Advances in diagnostic and therapy for rare hereditary haematological diseases (ARETHA Project)

Mayka Sánchez



Vall d'Hebron Institut de Recerca (VHIR)


Shared genetic architecture between inflammatory processes and depression: exploring genetic correlations, overlap and causality

Silvia Alemany &Maria Soler-Artigas


Impact of Neurodevelopmental Disorders on School Performance in 6,000 school-age children: genes and environment

Marta Ribasés & Judit Cabana


Retrospective exome reanalysis through literature search of new disease-associated genes *

Núria Martínez-Gil & Marta Codina



* indicates group has already accepted one student (some groups may accept more than one student)

The internatinal relationship office (ORI) at Biologia offers the possibility to apply for an ERASMUS Fellowship to do your TFM abroad. in this website you can check for mor info, or contact

International (ERASMUS) placements


Optogenetics and Chemical genetics tool development to study heart development in a simple marine chordate

International Center for Marine Molecular Biology (BERGEN)

Lionel Christiaen


RNA degradation by the exosome and its contribution to chromatin regulation and genome integrity

Department of Molecular Biosciences, The Wenner-Gren Institute (MBW), Stockholm University, Stockholm, Sweden

Neus Visa


Crosstalks between transcription, replication and genome stability

Institut de Génétique Moléculaire de Montpellier (IGMM)

Domenico Libri


Molecular basis of juvenile amyotrophic lateral sclerosis

Institut de Génétique Moléculaire de Montpellier (IGMM)

Odil Porrua


Early embryo development

Centre for Regenerative Medicine, Institute for Stem Cell Research, The University of Edinburgh.

Anahi Binagui (Valerie Wilson's Lab)


Enhancer dissection at disease-associated loci with CRISPR and base editing

St. Anna Kinderkrebsforschung (Children's cancer research institute)

Davide Seruggia


Does regeneration re-use developmental gene regulatory networks?

IGFL Lyon, France

Mathilde Paris


Multi-omics characterization of skeletal muscle in health and disease

IGBMC Strasbourg, France

Alix Simon and Jocelyn Laporte


Pathomechanism and treatment of neuromuscular diseases

IGBMC Strasbourg, France

Jocelyn Laporte