Histology

Presentation

The Histology Unit imparts teaching in various subjects and optional subjects of different degrees in the fields of Medicine and Health Sciences, both at the Bachelor's Degree (Medicine, Biomedical Engineering and Biomedicine / Biomedical Sciences) and Master's Degree (Biomedicine and Neurosciences). With regard to research, the main investigators of the Unit investigate the physiopathological bases in neurodegenerative genetic diseases and the connective tissue, and in regenerative medicine.

Alberch Vié, Jordi Full professor alberch@ub.edu
Britó, Verónica Inés Assistant professor 
Serra-Hunter
veronica.brito@ub.edu
Campuzano Uceda, Victoria Assistant professor 
Serra-Hunter
vcampuzanou@ub.edu    
Canals Coll, Josep M. Associate professor jmcanals@ub.edu
Egea Guri, Gustavo Full professor gegea@ub.edu
Ginés Padrós, Silvia
(Head Unit, phone no. 934035284)     
Associate professor silviagines@ub.edu
Giralt Torroella, Albert Res. postdoc. Ramón y Cajal albertgiralt@ub.edu    
Masana Nadal, Mercè Assistant professor mmasana@ub.edu
Mato Matute, Eugenia M. Assistant professor ematom@ub.edu
Muñoz Alarcón, M. Teresa Laboratory technician mtmunoz@ub.edu
Pérez Navarro, Esther Associate professor estherperez@ub.edu
Daniel Tornero Prieto Assistant professor daniel.tornero@ub.edu    

Dynamics and effective connectivity in bi- and three-dimensional neuronal cultures: from self-organization to engeneering
By: Estefanía Estevez Priego
Directors: Daniel Tornero Prieto and Jordi Soriano Fradera
Note: Excellent Cum Laude
Universitat de Barcelona, Facultat de Medicina
November 2019

Deciphering neuronal network alterations of the basal ganglia circuit in Huntington's Disease
By: Sara Fernández García

Directors: Jordi Alberch Vié and Mercè Masana Nadal
Universitat de Barcelona, Facultat de Medicina
May 2019

Dual role of mTOR in Huntington’s disease: contribution to striatal neuronal survival and dysfunction
By: Jordi Creus Muncunill
Director: Esther Perez Navarro
Universitat de Barcelona, Facultat de Medicina
October 2018

Evaluation of therapeutic targets for the treatment of behavioral alterations and neuropathology in Huntington´s disease: The role of histone deacetylase 3 and p75 neurotrophin receptor
By: Nuria Suelves Caballol
Director: Sílvia Ginés
Universitat de Barcelona, Facultat de Medicina
July 2018

Neuronal differentiation and maturation of human pluripotent stem cells for modeling Huntington’s disease
By: Andrea Comella Bolla
Director: Josep M. Canals Coll
Universitat de Barcelona, Facultat de Medicina
July 2018

Dual role of Cdk5 in cognitive deficits and striatal vulnerability in Huntington´s disease
By: Elena Alvárez-Periel
Director: Sílvia Gines
Universitat de Barcelona, Facultat de Medicina
July 2018

Technological insights into a histopathological and protein composition analysis of aortic aneurysmsin marfan syndrome
By: Júlia López-Guimet
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
February 2018

Therapeutic strategies based on neuroprotective mechanisms of neurotrophic factors in Huntington's disease models
By: Alfonso Gerardo García Díaz Barriga
Director: Jordi Alberch Vié
Universitat de Barcelona, Facultat de Medicina
2018

Membrane trafficking of TGF-beta and transcriptome analysis in Marfan syndrome

By: Anna-Maria Elisa Siegert
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
October de 2017

Pkco and nuclear lamina alterations: involvement in huntington's disease pathophysiology
By: Rafael Alcalá Vida
Director: Esther Perez Navarro
Universitat de Barcelona, Facultat de Medicina
June 2017

Caracterización de factores implicados en el desarrollo estriatal
By: Inés Guardia Pena
Director: Josep M. Canals Coll
Universitat de Barcelona, Facultat de Medicina
March 2017

Papel de las disfunciones mitocondriales en la patologia de la enfermedad de Huntington

By: Marta Cherubini
Director: Sílvia Ginés
Universitat de Barcelona, Facultat de Medicina
December 2016

Development of new methods for the differentiation of hPSCs for Huntington’s disease
Tesi Internacional
By: Andreas Mezger
Director: Josep M. Canals Coll
Universitat de Barcelona, Facultat de Medicina
November 2016

Characterization of morphogenes and new transcription factors involved in the development of striatal Medium Spiny Neurons
By:  Mónica Pardo Muñoz
Director: Josep M. Canals Coll
Universitat de Barcelona, Facultat de Medicina
November 2016

Description and validation of new therapeutical targets to prevent neurodegenerative and cognitive deficits in Huntington's Disease
By: Maria del Mar Puigdellívol Cañadell
Director: Sílvia Gines
Universitat de Barcelona, Facultat de Medicina
September 2015

Papel del citoesqueleto de actina en la regulación de la H+-ATPasa vacuolar del complejo de Golgi
By: Carla Serra-Peinado
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
December 2014

Red blood cell dynamics: a refined study of the erythrocyte flicker
By: Michael Mell (Universidad Complutense de Madrid)
Co-directors: Gustavo Egea Guri and Francisco Monroy
Universitat de Barcelona, Facultat de Medicina
November 2014

Role of phospholipid synthesis and phospholipase C in the regulation of diacylglycerol required for membrane trafficking at the Golgi complex

By: Adrià Sicart Caselles
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
February 2014

Función de las fosfatasa de fosfolípidos LPP3 en las etapas tempranas de la vía secretora
By: Enrique Gutiérrez-Martínez
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
October 2013

Characterization of mechanisms underlying neuronal survival and plasticity in Huntington's disease
By: Marta Anglada Huguet
Qualification: Capaç Cum Laude
Director: Jordi Alberch Vié
Universitat de Barcelona, Facultat de Medicina
2013

Regulation of the PKA pathway as a therapy to improve both motor and cognitive dysfunction in Huntington’s disease
By: Shiraz Ziauddin Tyebji
Director: Esther Perez Navarro
Universitat de Barcelona, Facultat de Medicina
October 2014

Characterization of the mechanisms underlying alterations in macroautophagy and survival signaling in Huntington’s disease
By: Laura Rué Cabré
Director: Esther Perez Navarro
Universitat de Barcelona, Facultat de Medicina
July 2012

El citoesqueleto de espectrina y el complejo de Golgi. Implicaciones en su arquitectura y funcionalidad en el transporte secretor
By: Laia Salcedo-Sicilia
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
December 2012

Vías de señalización y potenciales agentes terapéuticos en un modelo in vitro de síndrome alcohólico fetal

By: Javier Selva Sánchez
Director: Gustavo Egea Guri
Universitat de Barcelona, Facultat de Medicina
February 2011

Estudio de la alteración de las vías de señalización implicadas en la disfunción neuronal en la enfermedad de Huntington: Evaluación de su aplicación como terapia preventiva de las deficiencias cognitivas
By: Olga Carreton Gómez
Qualification: Excel·lent Cum Laude
Director: Jordi Alberch Vié
Universitat de Barcelona, Facultat de Medicina
2011

Unrevealing the role of 4E-BP1 in the control of translation in Huntington’s disease striatum
By: Lluís Salvador Hernández
Director: Esther Perez Navarro

Degree: Medicina UB. Academic course: 2020-2021

Modulation of protein synthesis in striatal cells
By: Marina Hernán Godoy
Director: Esther Perez Navarro

Degree: Ciències Biomèdiques UB. Academic course: 2018-2019

Understanding the mechanism of corticostriatal optogenetic-induced recovery of Huntington disease symptoms
By: Clara Gort Paniello

Director: Jordi Alberch Vié

Impact Of Mechanical Forces In The Phenotypic Modulation Of Vascular Smooth Muscle Cells In Marfan syndrome
By: Carla Fernández Barceló
Co-directors: Gustavo Egea Guri and Júlia López-Guimet
Degree in Biomedicine. 2017

Blockade of small RNA in Huntington’s disease: a novel and promising therapeutic door
By: Marta García de Herreros
Director: Esther Perez Navarro. Co-supervisor: J. Creus
Degree: Medicina UB. Academic course: 2016-2017

Evaluation of Lamin B1 levels in different neuronal populations and their effects on nuclear morphology and function in Huntington’s disease
By: Killian Crespí.
Director: Esther Perez Navarro
Degree: Ciències Biomèdiques UB. Academic course: 2016-2017.

The role of Lamin B1 in Huntington’s disease: its implications in cognition and nuclear morphology alterations
By: Carla Castany
Director: Esther Perez Navarro
Degree: Biologia Humana UPF. Academic course: 2016-2017

Small RNAs derived from Huntington’s disease patients induce motor alterations and molecular abnormalities in mice.
By: Anna Guisado.
Director: Esther Perez Navarro.
Co-supervisor: J. Creus.
Degree: Ciències Biomèdiques UB. Academic course: 2016-2017.

Paradigma de la recerca translacional en els aneurismes d’aorta.
By: Alba Prieto Fitó.
Director: Gustavo Egea
Fac. Medicina. 2016.

Intracellular signalling in Huntington’s disease: Analysis of a possible increased protein synthesis.
By: Raquel Badillos
Director: Esther Perez Navarro
Degre: Ciències Biomèdiques UB. Academic course: 2015-2016

Expresión diferencial de genes de la ruta del TGF-β en células vasculares del músculo liso en modelos experimentales del sindrome de Marfan.
By: Andrea Peiró Aubalat
Co-directors: Gustavo Egea Guri and Darya Gorbenko del Blanco
Degree in Biomedicine. 2015

The role of the extracellular matrix in the phenotype of aortic vascular smooth muscle cells in Marfan syndrome.
By: Roser Pons Cursach
Co-director: Gustavo Egea Guri and Elisabet Sarri Plans
Degree in Biomedicine, 2015

Role of PKC in STEP cleavage by calpains.
By: Silvia Cases
Co-supervisor: A. Saavedra
Director: Esther Perez Navarro
Degree: Biomedicina UdL. Academic course: 2013-2014

Regulation of mTORC1 and mTORC2 activity in Huntington’s disease striatum.
By: Jordi Creus
Director: Esther Perez Navarro
Degree: Ciències Biomèdiques. UB. Academic course: 2012-2013.

Study of the alterations in the neurodevelopment of lysosomal storage disease using cell cultures derived from human iPSCs
By: Carla Dumitrasco
Director: Daniel Tornero Prieto
Interuniversity Master in Neurosciences. Date of defense: 05/07/2021

Deciphering the exon1-production in Huntington disease pathology
By: Nerea Garcia Hernaez
Co-directors: Verónica Inés Britó and Sílvia Ginés Padrós
Interuniversity Master in Neurosciences. Academic course: 2019-2020

Understanding the molecular mechanism of corticostriatal optogenetic-induced recovery of Huntington disease symptoms
By: Clara Gort-Paniello
Director: Mercè Masana Nadal
Interuniversity Master in Neurosciences. Academic course: 2019-2020

Do alterations in translation induced by mutant huntingtin depend on the number of CAG repeats?
By: Irene De la Calle Fuentes
Director: Esther Pérez Navarro
Interuniversity Master in Neurosciences. Academic course: 2019-2020

Dissociation of embryonic mouse striatum for single cell analysis: An improvement on the generation of single-cell suspensions from mouse embryonic neural tissue
By: Xavier Alarcón Masferrer
Directores: Daniel Tornero Prieto and Josep M. Canals
Interuniversity Master in Neurosciences. Date of defense: 17/09/19

Sertraline-mediated protein synthesis normalization as a possible novel treatment for Huntington's disease.
By: Uxue Balantzategi
Director: Esther Pérez Navarro
Interuniversity Master in Neurosciences. Academic course: 2018-2019

Avaluació de NPT520-35 al model transgènic de la malaltia de Huntington R6/1
By: Javier David Lluesma
Director: Esther Pérez Navarro
Interuniversity Master in Neurosciences. Academic course: 2018-2019

Helios transcription factor regulates WDFY1 and associated schizophrenia-like pehnotypes
By: Belissa Fernandez
Director: Albert Giralt Torroella
Interuniversity Master in Neurosciences. Academic course: 2018-2019

Decoding the role of Ikaros in neuroinflamation and schizophrenia-related phenotypes
By: Jessica Fernandez
Director: Albert Giralt Torroella
Interuniversity Master in Neurosciences. Academic course: 2018-2019

Superoxide Dismutase 2: its role in the oxidative stress in Marfan Syndrome
By: Isaac Rodríguez Rovira
Director: Gustavo Egea Guri.
Master Translational Medicine, 2018

Optogenetic stimulation of corticostriatal pathway recovers motor impairments inr6/1 model of Huntington's disease
By: Sara Conde Berriozabal
Director: Jordi Alberch Vié
Universitat de Barcelona, Facultat de Medicina, 2018

Protein synthesis as a novel biomarker in Huntington’s disease
By: Carla Castany
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course: 2017-2018

Involvement of small RNAs in the pathophysiology of Huntington’s disease: focus on sCAG species.
By: Anna Guisado
Director: Esther Perez Navarro
Co-supervisor: E. Martí
Interuniversity Master in Neurosciences. Academic course: 2017-2018

Identification and validation of therapeutic targets and biomarkers in Huntington’s Disease
By: Anika Pupak
Co-directors: Verónica Inés Britó and Sílvia Ginés Padrós
Interuniversity Master in Neurosciences. Academic course: 2017-2018

Elucidating the communication between neurons and astrocytes in temporal lobe epilepsy: role of the BDNF-TrkB Pathway
By: Anna Sancho Balsells
Director: Albert Giralt Torroella
Interuniversity Master in Neurosciences. UPMC (França). Academic course: 2017-2018

Caracterización de alteracions en los circuitos de los ganglios basales en la enfermedad de Huntington
By: Ened Rodríguez Urgellés
Director: Jordi Alberch Vié
Universitat de Barcelona, Facultat de Medicina, 2017

Increased protein translation as a new pathogenic mechanism in Huntington’s disease
By: Raquel Badillos
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course: 2016-2017

The influence of physiologic stretching on Marfan vascular smooth muscle cells’ phenotype and their cytoskeleton organization
By:
Nacho Ruíz Jiménez
Co-directors: Gustavo Egea Guri and Júlia López-Guimet.
Master in Biomedicine, 2016

Segmentation and 3D reconstruction of aortic tomographic images of Marfan syndrome murine model
By: Lucía Peña Pérez.
Co-directors: Gustavo Egea Guri and Bart Bijnens (UPF)
Master in Biomedicine, 2016

Pyk2 and Alzheimer disease
By: Amel Tamila Farah
Director: Albert Giralt Torroella
Master's Degree in Biology (UPMC, Paris, France). Academic course: 2015-2016

Títol:
By: Ferran Lugo Hernández
Director: Mercè Masana Nadal
Interuniversity Master in Neurosciences. Academic course: 2015-2016

Expression of β1 integrin is down-regulated in patients with Marfan syndrome
By: Laia Yáñez Bisbe
Director: Gustavo Egea Guri.
Master Translational Medicine, 2015

Characterization of STEP levels and function during aging
By: Silvia Cases
Director: Esther Perez Navarro
Co-supervisor: A. Saavedra
Interuniversity Master in Neurosciences. Academic course 2014-2015

Role of STEP in the cognitive and motor decline occurring in Huntington’s disease
By: Sara Martínez.
Director: Esther Perez Navarro
Co-supervisor: G. Azkona
Interuniversity Master in Neurosciences. Academic course 2014-2015

Characterization of nuclear morphological alterations related to increased levels of lamin B in Huntington’s disease
By: Marta Garcia
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2014-2015

Pyk2 and Alzheimer disease
By: Benoit de Pins
Director: Albert Giralt Torroella
Master in Biology (UPMC, Paris. França). Academic course 2014-2015.

mTORC2 activity is increased in Huntington’s disease striatum: Role of Rictor
By: Jordi Creus.
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2013-2014

Role of STEP in hyperalgesia
By: David Aluja
Co-supervisor: G. Azkona
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2013-2014

Paper del receptor p75 en els dèficits cognitius de la malaltia de Huntington
By: Nuria Suelves
Co-directors: Verónica Inés Britó and Sílvia Ginés Padrós
Interuniversity Master in Neurosciences. Academic course 2013-2014

Study of the alterations in macroautophagy induced by aging
By: Laura Vidal
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2011-2012

Regulation of PKC delta in Huntington’s disease
By: Graciela López-Soop
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2010-2011

Role of cGMP/PKG in motor and cognitive dysfunction in HD
By: Helena Arumí
Director: Esther Perez Navarro
Co-supervisor: A. Saavedra
Interuniversity Master in Neurosciences. Academic course 2010-2011

Study of the pro-apoptotic function of PKC delta in an in vitro model of Huntington’s disease
By: Rafael Alcalá
Director: Esther Perez Navarro
Interuniversity Master in Neurosciences. Academic course 2010-2011

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