Para más información sobre las publicaciones del IP del grupo pueden visitar el siguiente enlace:
ORCID: https://orcid.org/0000-0002-6154-8323
ResearcherID: http://www.researcherid.com/rid/T-9630-2017
Loop profile: https://loop.frontiersin.org/people/21648/overview
Martínez-Alberquilla, I.; Gasull, X.; Pérez-Luna, P.; Seco-Mera, R.; Ruiz-Alcocer, J.; Crooke, A. Neutrophils and neutrophil extracellular trap components: emerging biomarkers and therapeutic targets for age-related eye diseases. Ageing Res Rev. 2022 Feb;74: 101553. doi: 10.1016/ j.arr.2021. 101553. Epub 2021 Dec 28. PMID: 34971794
Radosevic, M.; Planagumà, J.; Mannara, F.; Mellado, A.; Aguilar, E.; Sabater, L.; Landa, J.; García-Serra, A.; Maudes, E.; Gasull, X.; Lewis, M.; Dalmau, J. Allosteric Modulation of NMDARs Reverses Patients' Autoantibody Effects in Mice. Neurol Neuroimmunol Neuroinflamm 2021 Dec 13;9 (1):e1122. doi: 10.1212/ NXI. 0000000000001122. Print 2022 Jan. PMID: 34903638
Andres-Bilbe, A.; Castellanos, A.; Pujol-Coma, A.; Callejo, G.; Comes, N.; Gasull, X. The background K+ channel TRESK in sensory physiology and pain. Front Physiol. 2021 Oct 1; 12:691045. doi: 10.3389/ fphys. 2021.691045. eCollection 2021. PMID: 34658903
Rezola, M.; Castellanos, A.; Gasull, X.; Comes, N. Functional Interaction Between Caveolin 1 and LRRC8-Mediated Volume-Regulated Anion Channel. Front Physiol. 2021 Oct 1; 12:691045. doi: 10.3389/ fphys. 2021.691045. eCollection 2021. PMID: 34658903
Pérez-Sisqués, L.; Martín-Flores, N.; Masana, M.; Solana-Balaguer, J.; Llobet, A.; Romaní-Aumedes, J.; Canal, M.; Campoy-Campos, G.; García-García, E.; Sánchez-Fernández, N.; Fernández-García, S.; Gilbert, J.P.; Rodríguez, M.J.; Man, H.Y.; Feinstein, E.; Williamson, D.L.; Soto, D.; Gasull, X.; Alberch, J.; Malagelada, C. RTP801 regulates motor cortex synaptic transmission and learning. Exp. Neurol. 2021 Aug. 342: 113755. doi: 10.1016/ j.expneurol. 2021.113755. Epub 2021 May 11. PMID: 33984337
Landa, J.; Guasp, M.; Míguez-Cabello, F.; Guimarães, J.; Mishima, T.; Oda, F.; Zipp, F.; Krajinovic, V.; Fuhr, P.; Honnorat, J.; Titulaer, M.; Simabukuro, M.; Planagumà, J.; Martínez-Hernández, E.; Armangué, T.; Saiz, A.; Gasull, X.; Soto, D.; Graus, F.; Sabater, L.; Dalmau, J.; GluK2 encephalitis study group. Encephalitis with Autoantibodies against the Glutamate Kainate Receptors GluK2. Ann Neurol. 2021 Jul; 90(1): 101-117. doi: 10.1002/ ana.26098. Epub 2021 May 17. PMID: 33949707
Mannara, F.; Radosevic, M.; Planagumà, J., Soto, D.; Aguilar, E.; García-Serra, A.; Maudes, E.; Pedreño, M.; Paul, S.; Doherty, J.; Quirk, M.; Dai, J.; Gasull, X.; Lewis, M.; Dalmau, J. Allosteric modulation of NMDA receptors prevents the antibody effects of patients with anti-NMDAR encephalitis. Brain. 2020 Sep 1; 143(9): 2709-2720. doi: 10.1093/ brain/awaa195. PMID: 32830245
Miguez-Cabello, F.; Sánchez-Fernández, N.; Yefimenko, N.; Gasull, X.; Gratacòs-Batlle, E.; Soto, D. AMPAR/TARP stoichiometry differentially modulates channel properties. Elife. 2020 May 26; 9: e53946. doi: 10.7554/ eLife.53946. PMID: 32452760
Castellanos A, Pujol-Coma A, Andres-Bilbe A, Negm A, Callejo G, Soto D, Noël J, Comes N, Gasull X. TRESK background K+ channel deletion selectively uncovers enhanced mechanical and cold sensitivity. J Physiol. 2020 Mar; 598(5): 1017-1038. doi: 10.1113/ JP279203. PMID: 31919847
Jérôme Busserolles J, Gasull X, Noël J. Potassium Channels and Pain. In: The Oxford Handbook of the Neurobiology of Pain. Edited by John N. Wood. Oxford University Press. Dec 2019 DOI: 10.1093/ oxfordhb/ 9780190860509.013. 19. ISBN: 9780190860509
Soto D, Olivella M, Grau C, Armstrong J, Alcon C, Gasull X, Santos-Gómez A, Locubiche S, Gómez de Salazar M, García-Díaz R, Gratacòs-Batlle E, Ramos-Vicente D, Chu-Van E, Colsch B, Fernández-Dueñas V, Ciruela F, Bayés À, Sindreu C, López-Sala A, García-Cazorla À, Altafaj X. l-Serine dietary supplementation is associated with clinical improvement of loss-of-function GRIN2B-related pediatric encephalopathy. Sci Signal. 2019 Jun 18;12 (586). pii: eaaw0936. doi: 10.1126/ scisignal.aaw0936. PMID: 31213567
Coombs ID, Soto D, McGee TP, Gold MG, Farrant M, Cull-Candy SG. Homomeric GluA2(R) AMPA receptors can conduct when desensitized. Nat Commun. 2019 Sep 20;10(1): 4312. doi: 10.1038/ s41467-019-12280-9. PMID: 31541113
Ramos-Vicente D, Ji J, Gratacòs-Batlle E, Gou G, Reig-Viader R, Luís J, Burguera D, Navas-Perez E, García-Fernández J, Fuentes-Prior P, Escriva H, Roher N, Soto D, Bayés À. Metazoan evolution of glutamate receptors reveals unreported phylogenetic groups and divergent lineage-specific events. Elife. 2018; 7: e35774. doi: 10.7554/ eLife.35774. PMID: 30465522
Pérez-Verdaguer M, Capera J, Ortego-Domínguez M, Bielanska J, Comes N, Montoro RJ, Camps M, Felipe A.Caveolar targeting links Kv1.3 with the insulin-dependent adipocyte physiology. Cell Mol Life Sci. 2018 Nov;75(21): 4059-4075. doi: 10.1007/ s00018-018-2851-7. Epub 2018 Jun 11. PMID: 29947924
Gasull X, Castany M, Castellanos A, Rezola M, Andrés-Bilbé A, Canut MI, Estévez R, Borrás T, Comes N. The LRRC8-mediated volume-regulated anion channel is altered in glaucoma. Sci Rep. 2019 Apr 1;9(1): 5392. doi: 10.1038/ s41598-019- 41524-3. PMID:
Royal P, Andres-Bilbe A, Ávalos Prado P, Verkest C, Wdziekonski B, Schaub S, Baron A, Lesage F, Gasull X, Levitz J, Sandoz G. Migraine-Associated TRESK Mutations Increase Neuronal Excitability through Alternative Translation Initiation and Inhibition of TREK. Neuron. 2019 Jan 16;101 (2): 232-245.e6. doi: 10.1016 /j.neuron. 2018.11.039. Epub 2018 Dec 17. PMID: 30573346
Petit-Pedrol M, Sell J, Planagumà J, Mannara F, Radosevic M, Haselmann H, Ceanga M, Sabater L, Spatola M, Soto D, Gasull X, Dalmau J, Geis C. LGI1 antibodies alter Kv1.1 and AMPA receptors changing synaptic excitability, plasticity and memory. Brain. 2018 Nov 1;141(11): 3144-3159. doi: 10.1093/ brain/ awy253. PMID: 30346486
Gratacòs-Batlle E, Olivella M, Sánchez-Fernández N, Yefimenko N, Miguez-Cabello F, Fadó R, Casals N, Gasull X, Ambrosio S, Soto D. Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement. Front Mol Neurosci. 2018 Aug 8;11:275. doi: 10.3389/ fnmol.2018.00275. eCollection 2018. PMID: 30135643
Elorza-Vidal X, Sirisi S, Gaitán-Peñas H, Pérez-Rius C, Alonso-Gardón M, Armand-Ugón M, Lanciotti A, Brignone MS, Prat E, Nunes V, Ambrosini E, Gasull X, Estévez R. GlialCAM/MLC1 modulates LRRC8/VRAC currents in an indirect manner: Implications for megalencephalic leukoencephalopathy. Neurobiol Dis. 2018 Nov;119:88-99.
Haselmann H, Mannara F, Werner C, Planagumà J, Miguez-Cabello F, Schmidl L, Grünewald B, Petit-Pedrol M, Kirmse K, Classen J, Demir F, Klöcker N, Soto D, Doose S, Dalmau J, Hallermann S, Geis C. Human Autoantibodies against the AMPA Receptor Subunit GluA2 Induce Receptor Reorganization and Memory Dysfunction. Neuron. 2018 Aug 18. pii: S0896-6273(18)30646-9. doi: 10.1016/j.neuron.2018.07.048. [Epub ahead of print]
Gratacòs-Batlle E, Olivella M, Sánchez-Fernández N, Yefimenko N, Miguez-Cabello F, Fadó R, Casals N, Gasull X, Ambrosio S, Soto D. Mechanisms of CPT1C-Dependent AMPAR Trafficking Enhancement. Front Mol Neurosci. 2018 Aug 8;11:275
Giblin JP, Etayo I, Castellanos A, Andres-Bilbe A, Gasull X. Anionic Phospholipids Bind to and Modulate the Activity of Human TRESK Background K+ Channel. Mol Neurobiol. 2018 Jul 23. doi: 10.1007/s12035-018-1244-0. [Epub ahead of print]
Leiva R, Phillips MB, Turcu AL, Gratacòs-Batlle E, León-García L, Sureda FX, Soto D, Johnson JW, Vázquez S. Pharmacological and Electrophysiological Characterization of Novel NMDA Receptor Antagonists. ACS Chem Neurosci. 2018 Jun 1. doi: 10.1021/acschemneuro.8b00154. [Epub ahead of print]
Castellanos A, Andres A, Bernal L, Callejo G, Comes N, Gual A, Giblin JP, Roza C, Gasull X. Pyrethroids inhibit K2P channels and activate sensory neurons: basis of insecticide-induced paraesthesias. Pain. 2018 Jan;159(1):92-105
Gaitán-Peñas H, Apaja PM, Arnedo T, Castellanos A, Elorza-Vidal X, Soto D, Gasull X, Lukacs GL, Estévez R. Leukoencephalopathy-causing CLCN2 mutations are associated with impaired Cl- channel function and trafficking. J Physiol. 2017 Nov 15;595(22):6993-7008
Carreon TA, Castellanos A, Gasull X, Bhattacharya SK. Interaction of cochlin and mechanosensitive channel TREK-1 in trabecular meshwork cells influences the regulation of intraocular pressure. Sci Rep. 2017 Mar 28; 7(1):452.
Sirisi S, Elorza-Vidal X, Arnedo T, Armand-Ugón M, Callejo G, Capdevila-Nortes X, López-Hernández T, Schulte U, Barrallo-Gimeno A, Nunes V, Gasull X*, Estévez R*. Depolarization causes the formation of a ternary complex between GlialCAM, MLC1 and ClC-2 in astrocytes: implications in megalencephalic leukoencephalopathy. Hum Mol Genet. 2017 Apr 7. [Epub ahead of print] *co-senior author
Martínez-Mármol R, Styrczewska K, Pérez-Verdaguer M, Vallejo-Gracia A, Comes N, Sorkin A, Felipe A. Ubiquitination mediates Kv1.3 endocytosis as a mechanism for protein kinase C-dependent modulation. Scientific Reports, 2017, 10(7): 42395.
Mirallave A, Morales M, Cabib C, Muñoz EJ, Santacruz P, Gasull X, Valls-Sole J. Sensory processing in Huntington's disease. Clin Neurophysiol. 2017 May; 128(5):689-696.
Kovács I, Luna C, Quirce S, Mizerska K, Callejo G, Riestra A, Fernández-Sánchez L, Meseguer VM, Cuenca N, Merayo-Lloves J, Acosta MC, Gasull X*, Belmonte C*, Gallar J*. Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease. Pain. 2016 Feb; 157(2):399-417. *co-senior author
Giblin JP, Comes N, Strauss O, Gasull X. Ion Channels in the Eye: Involvement in Ocular Pathologies. Adv Protein Chem Struct Biol. 2016: 104, pp.157-231.
López-Serrano C, Torres-Espín A, Hernández J, Alvarez-Palomo AB, Requena J, Gasull X, Edel MJ, Navarro X. Effects of the spinal cord injury environment on the differentiation capacity of human neural stem cells derived from induced pluripotent stem cells. Cell Transplant. 2016: 25, pp.1833-1852
Pérez-Verdaguer M, Capera J, Martínez-Mármol R, Camps M, Comes N, Tamkun MM, Felipe A. Caveolin interaction governs Kv1.3 lipid raft targeting. Scientific Reports, 2016, 2(6): 22453.
Martínez-Mármol R, Comes N, Pérez-Verdaguer M, Vicente R, Pujadas Ll, Soriano, E, Sorkin A, Felipe A. Unconventional EGF-induced ERK1/2-mediated Kv1.3 endocytosis. Cellular and Molecular Life Sciences 2016, 73(7): 1515-28.
Martínez-Mármol R, Barneda-Zahonero B, Soto D, Andrés RM, Coccia E, Gasull X, Planells-Ferrer L, Moubarak RS, Soriano E, Comella JX. FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration. Sci Rep. 2016 Oct 21; 6:35775.
Figueiro-Silva J, Gruart A, Clayton KB, Podlesniy P, Abad MA, Gasull X, Delgado-García JM, Trullas R. Neuronal pentraxin 1 negatively regulates excitatory synapse density and synaptic plasticity. J Neurosci. 2015 Apr 8; 35 (14):5504-21.
Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, Chrast R, Cull-Candy SG. (2015) Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons. J Physiol. 2015 Oct 1; 593(19):4373-86.
Espinosa-Parrilla JF, Martínez-Moreno M, Gasull X, Mahy N, Rodríguez MJ. The L-type voltage-gated calcium channel modulates microglial pro-inflammatory activity. Mol Cell Neurosci. 2015 Jan; 64:104-15.
Fadó R, Soto D, Miñano-Molina AJ, Pozo M, Carrasco P, Yefimenko N, Rodríguez-Álvarez J, Casals N (2015) Novel Regulation of the Synthesis of α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Subunit GluA1 by Carnitine Palmitoyltransferase 1C (CPT1C) in the Hippocampus. J Biol Chem. 2015 Oct 16; 290(42):25548-60.
Moreno C, Oliveras A, de la Cruz A, Bartolucci Ch, Muñoz C, Salar E, Gimeno JR, Severi S, Comes N, Felipe A, Gonzalez T, Lambiase P, Valenzuela C. A new KCNQ1 mutation at the S5 segment that impairs its association with KCNE1 is responsible for short QT syndrome. Cardiovascular Research 2015, 107(4): 613-23.
Moreno C, de la Cruz A, Oliveras A, Kharche SR, Guizy M, Comes N, Starý T, Ronchi C, Rocchetti M, Baró I, Loussouarn G, Zaza A, Severi S, Felipe A, Valenzuela C. Marine n-3 PUFAs modulate IKs gating, channel expression, and location in membrane domains. Cardiovascular Research 2015, (2): 223-32.
Gratacòs-Batlle E, Yefimenko N, Cascos-García H, Soto D (2015) AMPAR interacting protein CPT1C enhances surface expression of GluA1-containing receptors. Front Cell Neurosci. 2015 Feb 2; 8:469.
Comes N, Felipe A. Involvement of potassium channels in the progression of cancer to a more malignant phenotype. Biochimica et Biophysica Acta-Biomembranes 2015 Oct; 1848(10 Pt B):2477-92.
Callejo G, Castellanos A, Castany M, Gual A, Luna C, Acosta MC, Gallar J, Giblin JP, Gasull X. Acid-sensing ion channels detect moderate acidifications to induce ocular pain. Pain. 2015 Mar; 156(3) :483-95.
Soto D, Coombs ID, Gratacòs-Batlle E, Farrant M, Cull-Candy SG. (2014) Molecular mechanisms contributing to TARP regulation of channel conductance and polyamine block of calcium-permeable AMPA receptors. J Neurosci. 34 (35):11673-83.
Oliveras A, Roura-Ferrer M, Solé L, de la Cruz A, Prieto A, Etxebarria A, Manils J, Morales-Cano D, Condom E, Soler C, Cogolludo A, Valenzuela C, Villarroel A, Comes N, Felipe A. Functional assembly of Kv7.1/Kv7.5 channels with emerging properties on vascular muscle physiology. Arteriosc Thromb and Vasc Biol, 2014 (7): 1522-30.
Guzman-Aranguez A, Gasull X, Diebold Y, Pintor J. Purinergic receptors in ocular inflammation. Mediators Inflamm. 2014; 2014:320906.
