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A new study reveals the function of ‘corpora amylacea’ to remove brain waste substances

News | 03-12-2019

An article published in Proceedings of the National Academy of Sciences (PNAS) describes a new pathway in the central nervous system to expel waste substances from the brain through the creation of corpora amylacea (CA), aggregates formed by glucose polymers amassing waste products.

The study, which opens new views on the clinical practice regarding neurodegenerative diseases, is led by Carme Pelegrí and Jordi Vilaplana, lecturers from the Faculty of Pharmacy and Food Sciences, the Institute of Neurosciences (UBNeuro) of the University of Barcelona and the Biomedical Research Networking Center on Neurodegenerative Diseases (CIBERNED).   

Other participants in the study are Marta Riba and Elisabet Augé (Faculty of Pharmacy and Food Sciences, UB-UBNeuro and CIBERNED); Joan Campo, David Moral, Ruth Ferrer and Raquel Martín (Faculty of Pharmacy and Food Sciences and INSA-UB), and Laura Molina and Teresa Ximelis, from the Hospital Clinic de Barcelona Biobank Neurological Tissue Bank – IDIBAPS.

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