Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressants

TP53INP2-dependent activation of muscle autophagy ameliorates sarcopenia and promotes healthy aging

Binding of Cholesterol to the N-terminal Domain of the NPC1L1 Transporter: Analysis of the Epimerisation-Related Binding Selectivity and Loop Mutations

c-Jun N-terminal Kinase 1 ablation protects against metabolic-induced hippocampal cognitive impairments

11β-HSD1 Inhibition Rescues SAMP8 Cognitive Impairment Induced by Metabolic Stress

g-Nomic: a new pharmacogenetics interpretation software

Maternal Resveratrol Supplementation Prevents Cognitive Decline in Senescent Mice Offspring

Cancer immunotherapy using PolyPurine Reverse Hoogsteen hairpins targeting the PD-1/PD-L1 pathway in human tumor cells

Functional pharmacogenomics and toxicity of PolyPurine Reverse Hoogsteen hairpins directed against survivin in human cells

Tomato UDP-glucose sterol glycosyltransferases: A family of developmental and stress regulated genes that encode cytosolic and membrane-associated forms of the enzyme

Stereoselective preparation of quaternary 2-vinyl sphingosines and ceramides and their effect on basal sphingolipid metabolism

From the configurational preference of dihydroceramide desaturase-1 towards Δ6-unsaturated substrates to the discovery of a new inhibitor

The combination of MDPV and ethanol results in decreased cathinone and increased alcohol levels. Study of such pharmacological interaction

Evolutionary roots and diversification of the genus Aeromonas

New perspectives on corpora amylacea in the human brain

The Mediterranean diet and ADHD in children and adolescents

Dynamic undocking and the quasi-bound state as tools for drug discovery

Environmental enrichment modified epigenetic mechanisms in SAMP8 mouse hippocampus by reducing oxidative stress and inflammaging and achieving neuroprotection

Elucidation of the biosynthesis of carnosic acid and its reconstitution in yeast

Plasma miR-34a-5p and miR-545-3p as early biomarkers of Alzheimer's disease: potential and limitations

SIRT1 overexpression in mouse hippocampus induces cognitive enhancement through proteostatic and neurotrophic mechanisms

Suppressing farnesyl diphosphate synthase alters chloroplast development and triggers sterol-dependent induction of jasmonate- and Fe-related responses

Fructose, but not glucose, impairs insulin signaling in the three major insulin-sensitive tissues