J. Rozas, P. Librado, J. C. Sánchez-DelBarrio, X. Messeguer and R. Rozas
Universitat de Barcelona
Current Released Version: 5.10.1  (March 4, 2010)


DnaSP, DNA Sequence Polymorphism, is a software package for the analysis of nucleotide polymorphism from aligned DNA sequence data. DnaSP can estimate several measures of DNA sequence variation within and between populations (in noncoding, synonymous or nonsynonymous sites, or in various sorts of codon positions), as well as linkage disequilibrium, recombination, gene flow and gene conversion parameters. DnaSP can also carry out several tests of neutrality: Hudson, Kreitman and Aguadé (1987), Tajima (1989), McDonald and Kreitman (1991), Fu and Li (1993), and Fu (1997) tests. Additionally, DnaSP can estimate the confidence intervals of some test-statistics by the coalescent. The results of the analyses are displayed on tabular and graphic form.

More information

DnaSP User-Interface

Running DnaSP under Windows, Linux and MacIntosh

Bugs detected in DnaSP

New features in DnaSP versions 5.10

DnaSP version 5.10.1 (Self-extracting file of 4.6 Mb)

    Download DnaSP

     DnaSP Documentation  

    Having trouble downloading/running DnaSP?

Molecular Evolutionary Genetics Group Web 

VariScan Software 



Rozas, J. and Rozas, R. (1995). DnaSP, DNA sequence polymorphism: an interactive program for estimating Population Genetics parameters from DNA sequence data. Comput. Applic. Biosci. 11: 621-625.

Rozas, J. and Rozas, R. (1997). DnaSP version 2.0: a novel software package for extensive molecular population genetics analysis. Comput. Applic. Biosci. 13: 307-311.

Rozas, J. and Rozas, R. (1999). DnaSP version 3: an integrated program for molecular population genetics and molecular evolution analysis. Bioinformatics 15: 174-175.

Rozas, J., Sánchez-DelBarrio, J. C., Messeguer, X. and Rozas, R. (2003).  DnaSP, DNA polymorphism analyses by the coalescent and other methods. Bioinformatics 19: 2496-2497.

Librado, P. and Rozas, J. (2009). DnaSP v5: A software for comprehensive analysis of DNA polymorphism data. Bioinformatics 25: 1451-1452.

Rozas, J. (2009). DNA Sequence Polymorphism Analysis using DnaSP. Pp. 337-350. In Posada, D. (ed.) Bioinformatics for DNA Sequence Analysis; Methods in Molecular Biology Series Vol. 537. Humana Press, NJ, USA.


This is access number  since July 19, 1998

Web Page created on 1997
December 17, 2012

Back to Julio Rozas Home Page