Identificació de biomarcadors i validació de dianes: Articles

2021–

  • Diaz-Garrido, N.; Badia, J.; Baldoma, L. Modulation of Dendritic Cells by Microbiota Extracellular Vesicles Influences the Cytokine Profile and Exosome Cargo. Nutrients, 14, 2022, 344. https://doi.org/10.3390/nu14020344
  • Diaz-Garrido, N.; Cordero, C.; Olivo-Martinez, Y.; Badia, J.; Baldoma, L. Cell-to-Cell Communication by Host-Released Extracellular Vesicles in the Gut: Implications in Health and Disease. International Journal Of Molecular Sciences, 22, 2021, 2213. https://doi.org/10.3390/ijms22042213
  • Lopez-Machado, A.; Diaz, N.; Cano, A.; Espina, M.; Badia, J.; Baldoma, L.; Calpena, A.C.; Biancardi, M.; Souto, E.B.; Garcia, M.L.; Sanchez-Lopez, E.  Development of topical eye-drops of lactoferrin-loaded biodegradable nanoparticles for the treatment of anterior segment inflammatory processes. International Journal Of Pharmaceutics, 609, 2021, 121188. https://doi.org/10.1016/j.ijpharm.2021.121188
  • Diaz-Garrido, N.; Badia, J.; Baldoma, L. Microbiota-derived extracellular vesicles in interkingdom communication in the gut. Journal Of Extracellular Vesicles, 10, 2021, e12161. https://doi.org/10.1002/jev2.12161
  • Lopez-Machado, A.; Diaz-Garrido, N.; Cano, A.; Espina, M.; Badia, J.; Baldoma, L.; Calpena, A.C.; Souto, E.B; Garcia, M.L.; Sanchez-Lopez, E.  Development of Lactoferrin-Loaded Liposomes for the Management of Dry Eye Disease and Ocular Inflammation. Pharmaceutics, 13, 2021, 1698. https://dx.doi.org/10.3390%2Fpharmaceutics13101698
  • Folle, C.; Diaz-Garrido, N.; Sanchez-Lopez, E.; Marques, A.M.; Badia, J.; Baldoma, L.; Espina, M.; Calpena, A.C.; Garcia, M. L.  Surface-Modified Multifunctional Thymol-Loaded Biodegradable Nanoparticles for Topical Acne Treatment. Pharmaceutics, 13, 2021, 1501. https://doi.org/10.3390/pharmaceutics13091501
  • Bustos-Salgado, P.; Andrade-Carrera, B.; Dominguez-Villegas, V.; Diaz-Garrido, N.; Rodriguez-Lagunas, M.J.; Badia, J.; Baldoma, L.; Mallandrich, M.; Calpena-Campmany, A.; Garduno-Ramirez, M.L. Screening Anti-Inflammatory Effects of Flavanones Solutions. International Journal Of Molecular Sciences, 22, 2021, 8878. https://doi.org/10.3390/ijms22168878
  • de Atauri, P.; Tarrado-Castellarnau, M.; Tarrago-Celada, J.; Foguet, C.; Karakitsou, E.; Centelles, J.J.; Cascante, M. Integrating systemic and molecular levels to infer key drivers sustaining metabolic adaptations. PLOS Computational Biology, 17, 2021. https://doi.org/10.1371/journal.pcbi.1009234
  • Folle, C.; Marques, A.M.; Diaz-Garrido, N.; Espina, M.; Sanchez-Lopez, E.; Badia, J.; Baldoma, L.; Calpena, AC.; Garcia, M.L. Thymol-loaded PLGA nanoparticles: an efficient approach for acne treatment. Journal Of Nanobiotechnology, 19, 2021, 359. https://doi.org/10.1186/s12951-021-01092-z
  • Privat, C.; Madurga, S.; Mas, F.; Rubio-Martinez, J. Unravelling Constant pH Molecular Dynamics in Oligopeptides with Explicit Solvation Model. Polymers, 13, 2021, 3311. https://doi.org/10.3390/polym13193311
  • Limon, D.; Vila, S.; Herrera-Olivas, A.; Vera, R.; Badia, J.; Baldoma, L.; Planas, M.; Feliu, L.; Perez-Garcia, L. Enhanced cytotoxicity of highly water-soluble gold nanoparticle-cyclopeptide conjugates in cancer cells. Colloids And Surfaces B-Biointerfaces, 197, 2021, 111384. https://doi.org/10.1016/j.colsurfb.2020.111384

2016-2020

  • Sokovic Bajic, S.; Canas, M.-A.; Tolinacki, M.; Badia, J.; Sanchez, B.; Golic, N.; Margolles, A.; Baldoma, L.; Ruas-Madiedo, P.  Proteomic profile of extracellular vesicles released by Lactiplantibacillus plantarum BGAN8 and their internalization by non-polarized HT29 cell line. Scientific Reports, 10, 2020, 21829. https://doi.org/10.1038/s41598-020-78920-z
  • Lazaro, A.; Balcells, C.; Quirante, J.; Badia, J.; Baldoma, L.; Ward, J.S.; Rissanen, K.; Font-Bardia, M.; Rodriguez, L.; Crespo, M.; Cascante, M. Luminescent Pt-II and Pt-IV Platinacycles with Anticancer Activity Against Multiplatinum-Resistant Metastatic CRC and CRPC Cell Models. Chemistry-A European Journal, 26, 2020, 1947-1952. https://doi.org/10.1002/chem.201905325
  • Diaz-Garrido, N.; Bonnin, S.; Riera, M.; Gimenez, R.; Badia, J.; Baldoma, L. Transcriptomic microRNA Profiling of Dendritic Cells in Response to Gut Microbiota-Secreted Vesicles. Cells, 9, 2020, 1534. https://doi.org/10.3390/cells9061534
  • Grau, L.; Romero, M.; Viñas, M.; Privat-Contreras, C.; Presa, D.; Morral, J.; Pors, K.; Rubio-Martinez, J.; Pujol, M. D.  Multigran scale synthesis of polycyclic lactones and evaluation of antitumor and other biological properties. European Journal Of Medicinal Chemistry, 185, 2020, 111807. https://doi.org/10.1016/j.ejmech.2019.111807
  • Privat, C.; Madurga, S.; Mas, F.; Rubio-Martinez, J. On the Use of the Discrete Constant pH Molecular Dynamics to Describe the Conformational Space of Peptides. Polymers, 13, 2020, 99. https://doi.org/10.3390/polym13010099
  • Alvarez, C.-S.; Gimenez, R.; Canas, M.-A.; Vera, R.; Diaz-Garrido, N.; Badia, J.; Baldoma, L. Extracellular vesicles and soluble factors secreted by Escherichia coli Nissle 1917 and ECOR63 protect against enteropathogenic E. coli-induced intestinal epithelial barrier dysfunction. BMC Microbiology, 19, 2019, 166. https://doi.org/10.1186/s12866-019-1534-3
  • Gonzalez-Pizarro, R.; Parrotta, G.; Vera, R.; Sanchez-Lopez, E.; Galindo, R.; Kjeldsen, F.; Badia, J.; Baldoma, L.; Espina, M.; Garcia, M.L. Ocular penetration of fluorometholone-loaded PEG-PLGA nanoparticles functionalized with cell-penetrating peptides. Nanomedicine, 14, 2019, 3089-3104. https://doi.org/10.2217/nnm-2019-0201
  • Diaz-Garrido, N.; Fabrega, M.-J.; Vera, R.; Gimenez, R.; Badia, J.; Baldoma, L. Membrane vesicles from the probiotic Nissle 1917 and gut resident Escherichia coli strains distinctly modulate human dendritic cells and subsequent T cell responses. Journal Of Functional Foods, 61, 2019, 103495. https://doi.org/10.1016/j.jff.2019.103495
  • Diaz, N.; Vera, R.; Riera, M.; Fabrega, M.; Gimenez, R.; Badia, J.; Baldoma, L. Effect of Microbiota Membrane Vesicles on Human Dendritic Cells Activation And Derived T-Cell Effector Responses. Annals Of Nutrition And Metabolism, 74, 2019. http://dx.doi.org/10.1159/000496759
  • Vera, R.; Diaz, N.; Ormeno, M. L.; Acevedo, M.; Gimenez, R.; Badia, J.; Baldoma, L. Lactobacillus salivarius LPM01 (DSM 22150) reduces inflammation in cellular models of intestinal epithelium. Annals Of Nutrition And Metabolism , 74, 2019, 76. https://doi.org/10.1186/s40104-020-00488-5
  • Canas, M.-A.; Fabrega, M.-J.; Gimenez, R.; Badia, J.; Baldoma, L. Outer Membrane Vesicles From Probiotic and Commensal Escherichia coli Activate NOD1-Mediated Immune Responses in Intestinal Epithelial Cells. Frontiers In Microbiology, 9, 2018, 498. https://dx.doi.org/10.3389%2Ffmicb.2018.00498
  • Capilla, A. S.; Soucek, R.; Grau, L.; Romero, M.; Rubio-Martínez, J.; Caignard, D. H.; Pujol, M. D. Substituted tetrahydroisoquinolines: synthesis, characterization, antitumor activity and other biological properties. European Journal Of Medicinal Chemistry, 145, 2018, 51-63. https://doi.org/10.1016/j.ejmech.2017.12.098
  • Clemente, M.; Halil Polat, I.; Albert, J.; Bosque, R.; Crespo, M.; Granell, J.; Lopez, C.; Martinez, M.; Quirante, J.; Messeguer, R.; Calvis, C.; Badia, J.; Baldoma, L.; Font-Bardia, M.; Cascante, M. Platinacycles Containing a Primary Amine Platinum(II) Compounds for Treating Cisplatin-Resistant Cancers by Oxidant Therapy. Organometallics, 37, 2018, 3502–3514. https://doi.org/10.1021/acs.organomet.8b00206
  • Limon, D.; Fabrega, J.M.; Calpena, A.C.; Badia, J.; Baldoma, L.; Perez-Garcia, Ll. Multifunctional Serine Protease Inhibitor-Coated Water-Soluble Gold Nanoparticles as a Novel Targeted Approach for the Treatment of Inflammatory Skin Diseases. Bioconjugate Chemistry, 29, 2018, 1060–1072. https://doi.org/10.1021/acs.bioconjchem.7b00717
  • Sole, M.; Balcells, C.; Crespo, M.; Quirante, J.; Badia, J.; Baldoma, L.; Font-Bardia, M.; Cascante, M.  Synthesis, characterization and biological activity of new cyclometallated platinum(IV) complexes containing a para-tolyl ligand. Dalton Transactions, 47, 2018, 8956-8971. https://doi.org/10.1039/C8DT01124A
  • Reig, M.; Bosque, R.; Font-Bardia, M.; Calvis, C.; Messeguer, R.; Baldoma, L.; Badia, J.; Velasco, Dolores; Lopez, C. A study of the properties, reactivity and anticancer activity of novel N- methylated-3-thiazolyl or 3-thienyl carbazoles and their Pd(II) and Pt(II) complexes. Journal Of Inorganic Biochemistry, 184, 2018, 134-145. https://doi.org/10.1016/j.jinorgbio.2018.03.008
  • Fabrega, M.-J.; Rodriguez-Nogales, A.; Garrido-Mesa, J.; Algieri, F.; Badia, J.; Gimenez, R.; Galvez, J.; Baldoma, L.    Intestinal Anti-inflammatory Effects of Outer Membrane Vesicles from Escherichia coli Nissle 1917 in DSS-Experimental Colitis in Mice. Frontiers In Microbiology, 8, 2017, 1274. https://doi.org/10.3389/fmicb.2017.01274
  • Bauer, E.; Domingo, X.; Balcells, C.; Polat, I.H.; Crespo, M.; Quirante, J.; Badia, J.; Baldoma, L.; Font-Bardia, M.; Cascante, M. Synthesis, characterization and biological activity of new cyclometallated platinum(IV) iodido complexes. Dalton Transactions, 46, 2017, 14973-14987. https://doi.org/10.1039/C7DT03448B
  • Pey, J.; Jose-Eneriz, E.S.; Ochoa, M.C.; Apaolaza, I.; de Atauri, P.; Rubio, A.; Cendoya, X.; Miranda, E.; Garate, L.; Cascante, M.; Carracedo, A.; Agirre, X.; Prosper, F.; Planes, F.J. In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer. Scientific Reports, 7, 2017, 14358. https://doi.org/10.1038/s41598-017-14067-8
  • Albert, J.; Granell, J.; Duran, J.A.; Lozano, A.; Luque, A.; Mate, A.; Quirante, J.; Khosa, M.K.; Calvis, C.; Messeguer, R.; Baldoma, L.; Badia, J. Endo and exo cyclopalladated (E)-N-([1,1 ‘-biphenyl]-2-yl)-1-mesitylmethanimines: Anticancer, antibacterial and antioxidant activities. Journal Of Organometallic Chemistry, 839, 2017, 116-125. https://doi.org/10.1016/j.jorganchem.2017.04.002
  • Escolà, A.; Crespo, M.; López, C.; Quirante, J.; Jayaraman, A.; Polat, I.H.; Badía, J.; Baldomà, L.; Cascante, M. On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions. Bioorg Med Chem. 24(22), 2016,  5804-5815. doi: https://doi.org/10.1016/j.bmc.2016.09.037
  • Moran, M.C.; Forniés, I.; Ruano, M.A.; Busquets, M.A., Vinardell, M.P. Efficient encapsulation and release of RNA molecules from gelatin-based nanopartcicles. Colloids and Surfaces A, 516, , 2017, 226.
  • Vinardell, M.P.; Llanas, H.; Marics, L.; Mitjans, M. In vitro comparative skin irritation induced by nano and non-nano zinc oxide. Nanomaterials (Basel). 7. pii: E56. doi: https://doi.org/10.3390/nano7030056 , 2017.
  • Alvarez, CS.; Badia,J.; Bosch, M.; Giménez, R.; Baldomà, L. Outer membrane vesicles and soluble factors released by probiotic Escherichia coli Nissle 1917 and commensal ECOR63 enhance barrier function by regulating expression of tight junction proteins in intestinal epithelial cells. Frontiers in Microbiology, 7, 1981, 2016.
  • Cañas, M.A.; Giménez, R.; Fábrega, M.J.; Toloza, L.; Baldomà, L.; Badia, J. Outer membrane vesicles from the probiotic Escherichia coli Nissle 1917 and the commensal ECOR12 enter intestinal epithelial cells via clathrin-dependent endocytosis and elicit differential effects on DNA damage. PLoS One, 11(8), e0160374, 2016.
  • Escolà, A.; Crespo, M.; López, C.; Quirante, J.; Jayaraman, A.; Polat, I.H.; Badía, J.; Baldomà, L.; Cascante, M. On the stability and biological behavior of cyclometallated Pt(IV) complexes with halido and aryl ligands in the axial positions. Bioorg Med Chem. 24(22), 2016, 5804-5815.
  • Fábrega, M.J.; Aguilera, L.; Giménez, R.; Varela, E.; Cañas, M.A.; Antolin, M.; Badia, J.; Baldomà, L. Activation of immune and defense responses in the intestinal mucosa by outer membrane vesicles of commensal and probiotic Escherichia coli strains. Frontiers in Microbiology, 7, 705, 2016. doi: https://doi.org/10.3389/fmicb.2016.00705
  • García-Becerra, L.; Mitjans, M.; Rivas-Morales, C.; Verde-Star, J.; Oranday-Cárdenas, A.; Vinardell, M. P. Antioxidant comparative effects of two grape pomace Mexican extracts from vineyards on erythrocytes. Food Chem. 194, 1081, 2016.
  • Kwasigroch, B.; Escribano, E.; Morán, M.C.; Queralt, J.; Busquets, M.A.; Estelrich, J. Oil-in-water nanoemulsions are suitable for carrying hydrophobic compounds: Indomethacin as a model of anti-inflammatory drug. Int J Pharm. 515, 749, 2016.
  • Pérez-Cruz, C.; Cañas, MA.; Giménez, R.; Badia, J.; Mercade, E.; Baldomà, L.;, Aguilera, L. Membrane vesicles released by a hypervesiculating Escherichia coli Nissle 1917 tolR mutant are highlyheterogeneous and show reduced capacity for epithelial cell interaction and entry. PLoS One, 11(12), e0169186, 2016.
  • Pinazo, A.; Petrizelli, V.; Bustelo, M.; Pons, R.; Vinardell, M.P.; Mitjans, M.; Manresa, A.; Perez, L. New cationic vesicles prepared with double chain surfactants from arginine: Role of the hydrophobic group on the antimicrobial activity and cytotoxicity. Colloids Surf B Biointerfaces. 141, 19, 2016.
  • Moran, M.C.; Tozar, T.; Simon, A.; Dinache, A.; Smarandache, A., Andrei, I.R.; Boni, A.M.; Pascu, M.L., Cirisano, F.; Ferrari, M. Toxicity study in blood and tumor cells of laser produced medicines for applications in fabrics. Colloids and Surfaces B. 137, 91, 2016.
  • Nogueira, D.R.; Scheeren, L.E.; Macedo, L.B.; Marcolino, A.I.; Vinardell, M.P.; Mitjans, M.; Infante, M.R.; Farooqi, A.A.; Rolim, C.M. Inclusion of a pH-responsive amino acid-based amphiphile in methotrexate-loaded chitosan nanoparticles as a delivery strategy in cancer therapy. Amino Acids. 48, 157, 2016.
  • Nogueira-Librelotto DR, Scheeren LE, Vinardell MP, Mitjans M, Rolim CM. Chitosan-tripolyphosphate nanoparticles functionalized with a pH-responsive amphiphile improved the in vitro antineoplastic effects of doxorubicin. Colloids Surfaces B Biointerfaces. 147, 326, 2016.
  • Scheeren, L.E.; Nogueira, D.R.; Macedo, L.B.; Vinardell, M.P.; Mitjans, M.; Infante, M.R.; Rolim, C.M. PEGylated and poloxamer-modified chitosan nanoparticles incorporating a lysine-based surfactant for pH-triggered doxorubicin release. Colloids Surf B Biointerfaces. 138, 117, 2016.

2011-2015

  • Albert, J.; Bosque, R.; Crespo, M.; Granell, J.; López, C.; Martín, R.; González, A.; Jayaraman, A.; Quirante, J.; Calvis, C.; Badía, J.; Baldomà, L.; Font-Bardia, M.; Cascante, M.; Messeguer, R. Neutral and ionic platinum compounds containing a cyclometallated chiral primary amine: synthesis, antitumor activity, DNA interaction and topoisomerase I-cathepsin B inhibition. Dalton transactions 44(30), 2015, 13602-13614.
  • Baccarin, T.; Mitjans, M.; Lemos-Senna, E.; Vinardell MP. Protection against oxidative damage in human erythrocytes and preliminary photosafety assessment of Punica granatum seed oil nanoemulsions entrapping polyphenol-rich ethyl acetate fraction. Toxicol in vitro. 30, 421, 2015.
  • Ferreira, E.; Giménez, R.; Cañas, M.A.; Aguilera, L.; Aguilar, J.; Badia, J.; Baldomà, L. Glyceraldehyde-3-phosphate dehydrogenase is required for efficient repair of cytotoxic DNA lesions in Escherichia coli. Int. J. Biochem. & Cell Biol.,60, 202-216, 2015. doi: https://doi.org/10.1016/j.biocel.2015.01.008
  • Fornaguera, C.; Calderó, G.; Mitjans, M.; Vinardell, M.P.; Solans, C.; Vauthier, C. Interactions of PLGA nanoparticles with blood components: protein adsorption, coagulation, activation of the complement system and hemolysis studies. Nanoscale. 7, 6045, 2015.
  • Moran, M.C.; Rosell, N.; Ruano, M.A.; Busquets, M.A.; Vinardell, M.P. Gelatin-based nanoparticles as DNA delivery systems: synthesis, physicochemical and biocompatible characterization. Colloids and Surfaces B. 134, 156, 2015
  • Nogueira, D.R.; Scheeren, L.E.; Vinardell, M.P.; Mitjans, M.; Infante, M.R.; Rolim, C.M. Nanoparticles incorporating pH-responsive surfactants as a viable approach to improve the intracellular drug delivery. Mater Sci Eng C Mater Biol Appl. 57, 100, 2015.
  • Romero, M., M. Zanuy, E. Rosell, M. Cascante, J. Piulats, M. Font-Bardia, J. Balzarini, E. De Clerq & M. D. Pujol. Optimization of xanthatin extraction from Xanthium spinosum L. and its cytotoxic, anti-angiogenesis and antiviral properties. European Journal of Medicinal Chemistry, 90, 2015,  491-6.
  • Toloza, L.; Giménez, R.; Fábrega , M.J.; Alvarez, C.S.; Aguilera, L.; Cañas M.A.; Martín-Venegas, R.; Badia, J.; Baldoma, L. The secreted autotransporter toxin (Sat) does not act as a virulence factor in the probiotic Escherichia coli strain Nissle 1917. BMC Microbiol., 15, 250, 2015.
  • Vinardell, M.P. The use of non-animal alternatives in the safety evaluations of cosmetics ingredients by the Scientific Committee on Consumer Safety (SCCS). Regulatory Toxicology Pharmacology. 71, 198, 2015.
  • Vinardell, M.P.; Mitjans, M. Antitumor Activities of Metal Oxide Nanoparticles. Nanomaterials (Basel). 5, 1004, 2015.
  • Aguilera, L.; Toloza, L.; Giménez, R.; Odena, A.; Oliveira, E.; Aguilar, J.; Badia, J.; Baldomà, L. Proteomic analysis of outer membrane vesiclesfrom the probiòtic strain Escherichia coli Nissle 1917. Proteomics, 14, 222-229, 2014.
  • Albert, J., R. Bosque, M. Crespo, G. Garcia, J. Granell, C. Lopez, M. V. Lovelle, R. Qadir, A. Gonzalez, A. Jayaraman, E. Mila, R. Cortes, J. Quirante, C. Calvis, R. Messeguer, J. Badia, L. Baldoma & M. Cascante. Cyclopalladated primary amines: A preliminary study of antiproliferative activity through apoptosis induction. European Journal of Medicinal Chemistry, 84, 2014, 530-536.
  • Botta, A.; Martínez, V.; Mitjans, M.; Balboa, E.; Conde, E.; Vinardell, M.P. Erythrocytes and cell line-based assays to evaluate the cytoprotective activity of antioxidant components obtained from natural sources. Toxicol In Vitro. 28, 120, 2014
  • Escola, A., M. Crespo, J. Quirante, R. Cortes, A. Jayaraman, J. Badia, L. Baldoma, T. Calvet, M. Font-Bardia & M. Cascante. Exploring the Scope of Pt-2(4-FC6H4)(4)(mu-SEt2)(2) as a Precursor for New Organometallic Platinum(II) and Platinum(IV). Antitumor Agents. Organometallics, 33, 2014, 1740-1750.
  • Galbiati, V.; Bianchi, S.; Martínez, V.; Mitjans, M.; Corsini, E. NCTC 2544 and IL-18 production: a tool for the in vitro identification of photoallergens. Toxicol In Vitro. 28, 13, 2014
  • Obiol-Pardo, C., G. Alcarraz-Vizan, S. Diaz-Moralli, M. Cascante & J. Rubio-Martinez. Design of an interface peptide as new inhibitor of human glucose-6-phosphate dehydrogenase. Journal of Molecular Graphics & Modelling, 49, 2014, 110-117.
  • Morán, M.C.; Jorge, A.F.; Vinardell, M.P. Sustainable DNA release from chitosan/protein based-DNA gel particles. Biomacromolecules. 15, 3953, 2014.
  • Morán, M.C.; Vinardell, M.P.; Infante, M.R.; Miguel, M.G.; Lindman, B. DNA gel particles: an overview. Adv Colloid Interface Sci. 205, 240, 2014.
  • Nogueira, D.R.; Mitjans, M.; Rolim, C.M.; Vinardell, M.P. Mechanisms Underlying Cytotoxicity Induced by Engineered Nanomaterials: A Review of In Vitro Studies. Nanomaterials (Basel). 4, 454, 2014.
  • Nogueira, D.R.; Morán, M.C.; MItjans, M.; Pérez, L.; Ramos, D.; de Lapuente, J.; Vinardell. M.P. Lysine-based surfactants in nanovesicle formulations: the role of cationic charge position and hydrophobicity in in vitro cytotoxicity and intracellular delivery. Nanotoxicology, 8, 404, 2014.
  • Ferreira, E.; Giménez, R.; Aguilera, L.; Guzman, K.; Aguilar, J.; Badia, J.; Baldomà, L. Protein interaction studies point to new functions for Escherichia coli glyceraldehyde-3-phosphate dehydrogenase. Res.. Microbiol., 164, 145-154, 2013.
  • Talancon, D., C. Lopez, M. Font-Bardia, T. Calvet, J. Quirante, C. Calvis, R. Messeguer, R. Cortes, M. Cascante, L. Baldoma & J. Badia. Diastereomerically pure platinum(II) complexes as antitumoral agents. The influence of the mode of binding {(N), (N,O)(-) or (C,N)}(-) of (1S,2R) – (eta(5)-C5H5) Fe{(eta(5)-C5H4) – CH=N – CH(Me) – CH(OH) – C6H5) and the arrangement of the auxiliary ligands. Journal of Inorganic Biochemistry, 118, 2013, 1-12.
  • Aguilera, L.; Ferreira, E.; Giménez, R.; Fernández, F.J.; Taulés, M.; Aguilar, J.; Vega, M.C..; Badia, J.; Baldomà, L. Secretion of the housekeeping protein glyceraldehyde-3-phosphate dehydrogenase by the LEE-encoded type III secretion system in enteropathogenic Escherichia coli. Int. J. Biochem. & Cell Biol., 44(6), 955-962, 2012
  • Cortés, R.; Crespo, M.; Davin, L.; Martín, R.; Quirante, J.; Ruiz, D.; Messeguer, R.; Calvis, C.; Baldomà, L.; Badia, J.; Font-Bardía, M.; Calvet, T.; Cascante, M. Seven-membered cyclopatinated complexes as a new family of anticancer agents. X-Ray characterization and preliminary biological studies. European Journal of Medicinal Chemistry, 54, 557-566, 2012.
  • Obiol-Pardo, C., G. Alcarraz-Vizan, M. Cascante & J. Rubio-Martinez. Diphenyl Urea Derivatives as Inhibitors of Transketolase: A Structure-Based Virtual Screening. PLoS ONE, 7, 2012.
  • Zanuy, M.; Ramos-Montoya, A.; Villacañas, O.; Canela, N.; Miranda, A.; Aguilar, E.; Agell, N.; Bachs, O.; Rubio-Martinez, J.; Pujol, M.D.; Lee, WN.P.; Marin, S.; Cascante, M. Cyclin-dependent kinases 4 and 6 control tumor progression and direct glucose oxidation in the pentose cycle. Metabolomics, 8, 454-464, 2012.

2006-2010

  • Garces, F.; Fernández, F.J.; Montellà, C.; Penya-Soler, E.; Prohens, R.; Aguilar, J.; Baldomà, L.; Coll, M.; Badia, J.; Vega, M. C. Molecular architecture of the Mn2+ dependent lactonase UlaG reveals an RNase-like metallo-β-lactamase fold and a novel quaternary structure . J. Mol. Biol, 398(5), 36-38, 2010.
  • Harrak,Y.; Casula, G.; Basset, J.; Rosell, G.; Plescia, S.; Raffa, D.; Grazia Cusimano, M.; Pouplana, R.; Pujol, M.D. Synthesis, Anti-inflammatory Activity and in Vitro Antitumor Effect of a Novel Class of Cyclooxigenase Inhibitors: 4-(Aryloyl)phenyl methyl sulfones. Journal of Medicinal Chemistry, 53, 6560-6571, 2010.
  • Egea, L.; Giménez, R.; Lúcia, D.; Modolell, I.; Badía, J.; Baldoma, L.; Aguilar, J. Increased production of the ether-lipid platelet activating factor in intestinal epithelial cells infected by Salmonella enteritidis. Biochim. Biophys. Acta-Molecular and Cell Biology of Lipids, 1781, 270-276, 2008.
  • Egea, L.; Aguilera, L.; Giménez, R.; Sorolla, M.A.; Aguilar, J.; Badia, J.; Baldoma, L. Role of secreted glyceraldehyde-3-phosphate dehydrogenase in the infection mechanism of enterohemorrhagic and enteropathogenic Escherichia coli: interaction of the extracellular enzyme with human plasminogen and fibrinogen. Int. J. Biochem & Cell Biol. 39(6),1190-1203, 2007