Míriam successfully defended her PhD thesis entitled “Biophysical and structural approaches to discover small molecule modulators of challenging targets in cancer”. In her work she applied different computational and biophysical techniques to discover small molecule ligands for relevant proteins in cancer. All the hard work was truly reflected and both the defense and the results […]

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Salvatore successfully defended his PhD thesis entitled “Biophysical Techniques for the Investigation of Protein-Ligand Complexes”. In his work he applied different biophysical techniques to different projects with huge relevance in the drug discovery field. All the hard work was truly reflected and both the defence and the results were brilliant. You have a bright future […]

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Carles has contributed to writing a chapter about protein degradation, chemical probes and PROTACs, together with Dr Xavier Barril, in “The Discovery and Utility of Chemical Probes in Target Discovery“, a book of the Royal Society of Chemistry. We are very happy to announce that the book has already been published in e-Book format and […]

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Carles had the opportunity to explain and share the efforts of our project with PROTACs to improve CAR-T cell therapies. We want to thank “La Fundació Bosch i Gimpera” for taking the time and bringing science closer to people. You can find the complete interview here (catalan) and here (spanish).

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Our collaborative project between the Fundació Bosch i Gimpera and Vall Hebron Institute of Oncology (VHIO) to improve CAR immunotherapy with PROTAC molecules has been selected to be one of the 23 funded projects of the call “CaixaImpulse Validate” from la “Fundació la Caixa”. The aim is to help and accelerate the technology transfer of […]

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We have been funded with a project of the call for the Valorisation Fund (FVal) of the Fund for the Promotion of Innovation (F2I) from La Fundació Bosch i Gimpera. These grants are supported by the Secretary of Universities and Research of the Department of Business and Knowledge of the Generalitat de Catalunya and are […]

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Last Saturday we started the typical catalan “calçot season” with our Barril Lab team friends enjoying a great Calçotada Day! We prepared and we cooked the calçots and we also had time to walk around to vist the nice outskirts of the town. Looking forward to the next one!

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Today the group attended to the IV Biomed PhD Day at University of Barcelona. Salvo gave a talk about his work ‘Drugging the FBW7 E3 ligase with a fragment-based approach’ and Míriam presented a poster entitled Drugging Challenging E3 Ligases: A Novel Multidisciplinary Approach to Identify Small-Molecules that Bind FBW7. Congratulations on your great work!

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