Datasets

José M. Carbó, Theresa E. León, Joan Font-Díaz, Juan Vladimir De la Rosa, Antonio Castrillo, Felix R. Picard, Daniel Staudenraus, Magdalena Huber, Lídia Cedó, Joan Carles Escolà-Gil, Lucía Campos, Latifa Bakiri, Erwin F. Wagner, Carme Caelles, Thomas Stratmann, Jo A. Van Ginderachter and Annabel F. Valledor. Pharmacological activation of LXR alters the expression profile of tumor-associated macrophages and the abundance of regulatory T cells in the tumor microenvironment. Cancer Res. 2021 Feb 15;81(4):968-985.

Casanova-Acebes M, Menéndez-Gutiérrez MP, Porcuna J, Álvarez-Errico D et al. RXRs control serous macrophage neonatal expansion and identity and contribute to ovarian cancer progression. Nat Commun. 2020 Apr 3;11(1):1655.

Ana Ramón-Vázquez, Juan Vladimir de la Rosa, Carlos Tabraue, Felix Lopez, Bonifacio Nicolas Díaz-Chico, Lisardo Bosca, Peter Tontonoz, Susana Alemany, Antonio Castrillo. Common and Differential Transcriptional Actions of Nuclear Receptors Liver X Receptors α and β in Macrophages. Molecular and Cellular Biology Feb 2019, 39 (5) e00376-18

Walter W., Alonso-Herranz L, Trappetti V., Crespo I., Ibberson M., Cedenilla M., Karaszewska A., Núñez V., Xenarios I., Arroyo A.G., Sanchez-Cabo F., Ricote M. Deciphering the dynamic transcriptional and post-transcriptional networks of cardiac macrophages in the healthy heart and after myocardial injury. Cell reports. 2018 Apr 10;23(2):622-636.

Niell N, Larriba MJ, Ferrer-Mayorga G, Sánchez-Pérez I, Cantero R, Real FX, Del Peso L, Muñoz A, González-Sancho JM. The human PKP2/plakophilin-2 gene is induced by Wnt/β-catenin in normal and colon cancer-associated fibroblasts. Int J Cancer. 2018 Feb 15;142(4):792-804.

Nadal M, Prekovic S, Gallastegui N, Helsen C, Abella M, Zielinska K, Gay M, Vilaseca M, Taulès M, Houtsmuller AB, van Royen ME, Claessens F, Fuentes-Prior P, Estébanez-Perpiñá E.
Structure of the homodimeric androgen receptor ligand-binding domain. Nat Commun. 2017 Feb 6;8:14388. doi: 10.1038/ncomms14388.

García-Arévalo M, Alonso-Magdalena P, Servitja JM, Boronat-Belda T et al. Maternal Exposure to Bisphenol-A During Pregnancy Increases Pancreatic β-Cell Growth During Early Life in Male Mice Offspring. Endocrinology 2016 Nov;157(11):4158-4171.

Menéndez-Gutiérrez MP, Rőszer T, Fuentes L, Núñez V et al. Retinoid X receptors orchestrate osteoclast differentiation and postnatal bone remodeling. J Clin Invest 2015 Feb;125(2):809-23.

Marco Piva, Giacomo Domenici, Oihana Iriondo, Miriam Rábano, Bruno M Simoes, Valentine Comaills, Inmaculada Barredo, Jose A Lopez-Ruiz, Ignacio Zabalza, Robert Kypta & Maria d M Vivanco. Sox2 promotes tamoxifen resistance in breast cancer cells. EMBO Mol Med. 2014 Jan;6(1):66-79.

Zabalza, Robert Kypta & Maria d M Vivanco. Sox2 promotes tamoxifen resistance in breast cancer cells. EMBO Mol Med. 2014 Jan;6(1):66-79.

Mónica Pascual-García, Laura Rué, Theresa León, Josep Julve, José María Carbó, Jonathan Matalonga, Herbert Auer, Antonio Celada, Joan Carles Escolà-Gil, Knut R. Steffensen, Esther Pérez-Navarro and Annabel F. Valledor. Reciprocal Negative Cross-Talk between Liver X Receptors (LXRs) and STAT1: Effects on IFN- −γ Induced Inflammatory Responses and LXR-Dependent Gene Expression. J Immunol 2013; 190:6520-6532

Roszer T, Menéndez-Gutiérrez MP, Lefterova MI, Alameda D et al. Autoimmune kidney disease and impaired engulfment of apoptotic cells in mice with macrophage peroxisome proliferator-activated receptor gamma or retinoid X receptor alpha deficiency. J Immunol 2011 Jan 1;186(1):621-31.

Sevilla LM, Bayo P, Latorre V, Sanchis A, Pérez P. Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol 2010 Nov;24(11):2166-78.

MP Menéndez-Gutiérrez, J Porcuna, R Nayak, A Paredes, H Niu, V Núñez, A Paranjpe, MJ. Gómez, A Bhattacharjee, DJ Schnell, Fátima Sánchez-Cabo, JS Welch, N Salomonis, JA Cancelas, M Ricote. Retinoid X receptor promotes hematopoietic stem cell fitness and quiescence and preserves hematopoietic homeostasis. Blood 2023 Feb 9;141(6):592-608. 

Carceller-Zazo E, Sevilla LM, Pons-Alonso O, Chiner-Oms A, Amazit L, An Vu T, Vitellius G, Viengchareun S, Comas I, Jaszczyszyn Y, Abella M, Alegre-Martí A, Estébanez-Perpiñá E, Lombès M, and Pérez P. The mineralocorticoid receptor modulates timing and location of genomic binding by glucocorticoid receptor in response to synthetic glucocorticoids in keratinocytes. FASEB J 2023 Jan;37(1):e22709.

Carbó JM, León TE, Font-Díaz J, De la Rosa JV, Castrillo A, Picard FR, Staudenraus D, Huber M, Cedó L, Escolà-Gil JC, Campos L, Bakiri L, Wagner EF, Caelles C, Stratmann T, Van Ginderachter JA, Valledor AF. Pharmacologic Activation of LXR Alters the Expression Profile of Tumor-Associated Macrophages and the Abundance of Regulatory T Cells in the Tumor Microenvironment. Cancer Res. 2021 Feb 15;81(4):968-985.

Waddington, Kirsty; Papadaki, Artemis; Coelewij, Leda; Adriani, Marsilio; Nytrova, Petra; Kubala Havrdova, Eva; Fogdell-Hahn, Anna; Farrell, Rachel; Dönnes, Pierre; Pineda Torra, Ines; Jury, Elizabeth. Using serum metabolomics to predict development of anti-drug antibodies in multiple sclerosis patients treated with IFNβ. Front Immunol. 2020 Jul 17;11:1527.

Waddington, KE; Robinson, GA; Rubio-Cuesta, B; Chrifi-Alaoui, E; Andreone, S; Poon, KS; Ivanova, I; Martin-Gutierrez, L; Owen, DM; Jury, EC; Pineda-Torra, I. LXR directly regulates glycosphingolipid synthesis and affects human CD4+T cell function. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2017394118.

Robinson, GA; Waddington, KE; Coelewij, L; Peng, JJ; Naja, M; Wincup, C; Radziszewska, A; Peckham, H; Isenberg, DA; Ioannou, Y; Ciurtin, C; Pineda-Torra, I; Jury, EC. Increased apolipoprotein-B:A1 ratio predicts cardiometabolic risk in patients with juvenile onset SLE. EBioMedicine. 2021 Mar;65:103243.

Becares, N; Gage, MC; Voisin, M; Shrestha, E; Martin-Gutierrez, L; Liang, N; Louie, R; Pourcet, B; Pello, OM; Luong, TV; Goni, S; Pichardo-Almarza, C; Roberg-Larsen, H; Diaz-Zuccarini, V; Steffensen, KR; O’Brien, A; Garabedian, MJ; Rombouts, K; Treuter, E; Pineda-Torra, I. Impaired LXRα Phosphorylation Attenuates Progression of Fatty Liver Disease. Cell Rep. 2019 Jan 22;26(4):984-995.e6.

Gage, MC; Becares, N; Louie, R; Waddington, KE; Zhang, Y; Tittanegro, TH; Rodriguez-Lorenzo, S; Jathanna, A; Pourcet, B; Pello, OM; De la Rosa, JV; Castrillo, A; Pineda-Torra, I. Disrupting LXRα phosphorylation promotes FoxM1 expression and modulates atherosclerosis by inducing macrophage proliferation. Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):E6556-E6565.

Waddington, KE; Robinson, GA; Rubio-Cuesta, B; Chrifi-Alaoui, E; Andreone, S; Poon, KS; Ivanova, I; Martin-Gutierrez, L; Owen, DM; Jury, EC; Pineda-Torra, I. LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2017394118.

Robinson, GA; Peng, JJ; Peckham, H; Butler, G; Pineda-Torra, I; Ciurtin, C; Jury, EC. Investigating sex differences in T regulatory cells from cisgender and transgender healthy individuals and patients with autoimmune inflammatory disease: a cross-sectional study. Lancet Rheumatol. 2022 Aug 31;4(10):e710-e724.