Publications 2024

Molecular driving force of a small molecule-induced protein disorder-order transition

Targeting dihydroceramide desaturase 1 (Des1): Syntheses of ceramide analogues with a rigid scaffold, inhibitory assays, and AlphaFold2-assisted structural insights reveal cyclopropenone PR280 as a potent inhibitor

ProteoCure: A European network to fine-tune the proteome

Proximity-Induced Pharmacology for Amyloid-Related Diseases

A versatile luminescent probe for sensing and monitoring amyloid proteins

Reaction space charting as a tool in organic chemistry research and development

Enumerative Discovery of Noncanonical Polypeptide Secondary Structures

Drugs from drugs: New chemical insights into a mature concept

From canonical to unique: extension of a lipophilicity scale of amino acids to non-standard residues

Binding of Cholesterol to the N-Terminal Domain of the NPC1L1 Transporter: Analysis of the Epimerization-Related Binding Selectivity and Loop Mutations