A scientific team found a new metabolism regulation system for the brown adipose tissue using the kallikrein-kinin hormonal system, so far related to the physiology of the renal and cardiovascular system and inflammation and pain processes. This molecular auto-control system of lipidic metabolism, so far unknown, could help prevent the damaging effects derived from an excessive activation of the brown adipose tissue.
The new study, published in the journal Nature Communications, is led by Professor Francesc Villarroya, from the Faculty of Biology and the Institute of Biomedicine of the University of Barcelona (IBUB), and member of the Physiopathology of Obesity and Nutrition Networking Biomedical Research Centre (CIBERobn) from the Health Institute Carlos III. Other participants in the study are the experts from the University of Santiago de Compostela, Maastricht University (the Netherlands), and Humboldt University, the Center for Cardiovascular Research and Berlin Institute of Health (Germany).
Article reference:
Marion Peyrou, Rubén Cereijo, Tania Quesada-López, Laura Campderrós, Aleix Gavaldà-Navarro, Laura Liñares-Pose, Elena Kaschina, Thomas Unger, Miguel López, Marta Giralt & Francesc Villarroya. “The kallikrein–kinin pathway as a mechanism for auto-control of brown adipose tissue activity”. Nature Communciations, 11: 2132 (2020).
UB News [+]
