Institut de Biomedicina de la Universitat de Barcelona

Drug and target discovery for biomedical science

The Institute of Biomedicine of the University of Barcelona (IBUB) is a transversal research unit formed by some 40 groups from the Faculties of Biology, Chemistry and Pharmacy and Food Sciences. The IBUB was created in 2006 with the aim of identifying, beyond the traditional academic structures (departments and faculties), a set of laboratories with complementary scientific activity, capable of generating synergies.


Technology Transfer Opportunities

One of the key strengths of IBUB is its ability to successfully transfer knowledge to society



Research groups





The Institute of Biomedicine brings together highly qualified biomedical research personnel working in groups renowned for their excellence, and its founding collective’s indicators in scientific production and the raising of resources testify to the IBUB’s benchmark status in biomedical research in both Catalonia and the rest of Europe.

Research Programs

IBUB is comprised of research groups actively coordinated in the form of differents programs and nodes

Research Groups

IBUB consists of different specialized research groups


The need for a wider view on the metabolic syndrome

Marià Alemany, Prof. Emeritus, Fac. Biology, UB


April 8, 2024




Aula Graus, Ed. Durfort, Fac. Biology

Optimizing Molecular Conformations and Interactions for Drug Design

Julian Fuchs, Computational Chemistry at Boehringer Ingelheim


March 22, 2024




Aula Magna, Fac. Pharmacy

New mitochondrial mechanisms in health and disease

Marc Liesa Roig, IBMB, CSIC


March 11, 2024




Aula Graus, Ed. Durfort, Fac. Biology

Article of the month

Marco Bertolini, Lorena Mendive-Tapia, Ouldouz Ghashghaei, Abigail Reese, Charles Lochenie, Anna M. Schoepf, Miquel Sintes, Karolina Tokarczyk, Zandile Nare, Andrew D. Scott, Stephen R. Knight, Advait R. Aithal, Amit Sachdeva, Rodolfo Lavilla, Marc Vendrell

ACS Central Science

Nonperturbative Fluorogenic Labeling of Immunophilins Enables the Wash-free Detection of Immunosuppressan

Immunosuppressants are clinically approved drugs to treat the potential rejection of transplanted organs and require frequent monitoring due to their narrow therapeutic window. Immunophilins are small proteins that bind immunosuppressants with high affinity, yet there are no examples of fluorogenic immunophilins and their potential application as optical biosensors for immunosuppressive drugs in clinical biosamples. In the present work, we designed novel diazonium BODIPY salts for the site-specific labeling of tyrosine residues in peptides via solid-phase synthesis as well as for late-stage functionalization of whole recombinant proteins. After the optimization of a straightforward one-step labeling procedure for immunophilins PPIA and FKBP12, we demonstrated the application of a fluorogenic analogue of FKBP12 for the selective detection of the immunosuppressant drug tacrolimus, including experiments in urine samples from patients with functioning renal transplants. This chemical methodology opens new avenues to rationally design wash-free immunophilin-based biosensors for rapid therapeutic drug monitoring.


MCP Lab offers a predoctoral contract associated with a project of the AGAUR Program “Indústria del Coneixement”

Data límit

20/1/2024 - Send CV and motivation letter

ENDED- Call for 6 research initiation grants 2023-2024

Data límit

3 d'octubre 2023. Més informació: https://www.ub.edu/ibub/call-for-6-research-initiation-grants-2023-2024/ Convocatòria: https://seu.ub.edu/ajutsPublic/showPublicacion/441657


Institut de Biomedicina de la Universitat de Barcelona, IBUB

Departament de Bioquímica i Biomedicina Molecular

Facultat de Biologia / Secretaria IBUB & Bioinformàtica
Avda. Diagonal, 643
Edifici Prevosti, planta -1
08028 Barcelona

+34 606 14 87 72

Our partners