Cohesin is a protein that forms a ring-shaped complex which wraps and alters the DNA molecule shape. It moves through the DNA and creates specific loops in the genetic material which determine the architecture of the genome and gene expression. Some mutations in the genes of the cohesion complex are responsible for rare diseases (cohesinopathies),
The Early Drug Discovery Unit (EDDU) at the University of Barcelona has recently been awarded the prestigious TECNIO quality seal by the Government of Catalonia through ACCIÓ. This recognition identifies entities that develop and facilitate technology for companies, highlighting their capacity to transfer knowledge and technology to the productive sector. EDDU is led by Dr.
The 2nd edition of the IBUB Early Career Day will take place on May 16. It will be a day where IBUB’s young researchers can present their research in various formats, along with two engaging plenary sessions, culminating in prizes for the best presentations! Date: May 16, 2025Schedule: 8:00h – 17:00hVenue: Aula Magna, Faculty of
A unique initiative to add value to chemical compounds from universities & research centers across Spain, enabling their evaluation in biological assays for drug discovery.
EU-OPENSCREEN is a not-for-profit European Research Infrastructure Consortium (ERIC) for chemical biology and early drug discovery. We support all stages of a chemical tool development project, including assay adaptation, high-throughput screening and chemical optimisation of the resulting ‘hit’ compounds. EU-OPENSCREEN operates an open-access database and a unique, common compound collection. Our main library, the European
Glioblastoma multiforme is a very aggressive type of brain cancer, with no effective therapy, so it is classified as an unmet medical need. A team from Institut de Biomedicina de la Universitat de Barcelona (IBUB), led by the professor of the Faculty of Pharmacy and Food Sciences, Carmen Escolano, has received a grant from the
We present the IBUB researchers working in the field of rare diseases, each within their area of expertise. The Chair of Rare Diseases and the pharmaceutical company Pfizer are organizing a conference on March 7 where all the current work on rare diseases will be presented.
According to the dimensional view of mental disorders, psychosis is expressed on a continuum ranging from mild subclinical traits and experiences present in the general population (schizotypy) to clinical symptoms in patients diagnosed with the disorder. Numerous studies have explored the genetic link between schizophrenia and its subclinical expressions, but the results have been inconsistent.
Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to facilitate the uptake of glucose through tissues and organs, leading to an increase in blood glucose (chronic hyperglycaemia). Since skeletal muscle is the tissue that
#11F, International Day of Women and Girls in Science, we want to highlight the scientific talent of the women who drive research forward at #IBUB. They are not all of them, but they represent all of us. #11FdonesIBUB #11FdoneSTEMUB
