The mechanisms that cause the world’s most common chronic liver disease — Metabolic dysfunction-associated steatotic liver disease (MASLD) — to develop and progress are not still fully understood. Now, a study by the IBUB and University of Barcelona has identified a new factor involved in the development of the disease: the protein ENT1, which allows
Once again, IBUB is hosting the IBUB Research Day, an annual event that brings together the Institute’s researchers to share knowledge, welcome new members and foster networking across our research community. The event provides an opportunity to exchange ideas, build new connections and explore opportunities for collaboration and synergies among IBUB research groups. This year’s
After an injury, DNA not only alters its activity but also the way it is organized spatially within the cell nucleus. In this process, certain regions of DNA establish new physical contacts through chromatin loops that act as bridges, bringing together sequences that are far apart in the genome’s linear sequence. Now, a study has
The Medicinal Chemistry and Pharmacology (MCP) Research Group at the University of Barcelona is recruiting a predoctoral researcher to join a multidisciplinary PhD project focused on developing novel ligands targeting Alzheimer’s disease. The position is funded through the project “Decoding and Modulation of Imidazoline I2 Receptors: Modulatory Ligands for Alzheimer’s Disease (PID2025-171044OB-I00)”, within the Spanish
The AmyloidTech Research Group (NanoBIC) at the Faculty of Pharmacy and Food Sciences, University of Barcelona, is recruiting two highly motivated PhD candidates to join two innovative research projects. Available positions BRAIN-PD – Brain-on-Chip Model for Parkinson’s Disease An interdisciplinary project focused on brain organoids, biomarkers, biosensors, microfluidics and precision diagnostics for Parkinson’s disease. Download
Primary biliary cholangitis is a rare autoimmune disease that affects the liver and can progress to cirrhosis. It occurs when the immune system attacks the small bile ducts within the liver. As a result, bile builds up, leading to inflammation and progressive liver damage. Although a first-line treatment exists, 40% of patients do not respond
A study by the University of Barcelona has identified nearly 20 genes that could contribute to some people being more susceptible to depression, anxiety and traits such as irritability and neuroticism. These genes are regulated by the RBFOX1 gene, which acts as the central hub of a genetic network linked to several key processes in
In children and adolescents who have experienced child abuse, the body appears to remain in a state of alert for too long, and this situation can affect several bodily systems, such as the neuroendocrine, immune and metabolic systems. When this alert response is prolonged, it leads to cumulative wear and tear on all the biological
A research article published in Nature, one of the world’s leading scientific journals, has revealed new mechanisms by which cells preserve genome stability under replication stress. The study, entitled “Replication-stress-induced chromatin loops protect fork stability”, has been led by researchers from the Erasmus MC Cancer Institute and Oncode Institute (Rotterdam, the Netherlands), with the participation
A new research project aims to develop an innovative method to measure heat production in living organisms, opening new possibilities for studying energy metabolism at the molecular level. The project is led by Prof. Fèlix Ritort from the Institut de Nanociència i Nanotecnologia de la Universitat de Barcelona (IN2UB), and focuses on the physical principles underlying
