Regulation of Lipid Metabolism in Obesity and Diabetes Group

Western lifestyle has transformed obesity into an alarming epidemic. Of particular concern is the concurrent and parallel increase in the prevalence of the metabolic diseases associated with obesity, such as insulin resistance, type 2 diabetes and cardiovascular disease. The pathophysiology of obesity-induced insulin resistance is attributable to several metabolic derangements such as the ectopic deposition of fat in liver, muscle and pancreas, and the increase in adipose tissue inflammation. Our group is interested in studying the molecular mechanisms implicated in the pathogenesis of obesity and type 2 diabetes. 

 

PhD or Postdoc positions availablec The REGULATION OF LIPID METABOLISM IN OBESITY AND DIABETES GROUP is looking for graduated students in Pharmacy, Biology, Biochemistry, Chemistry, Medicine or related degrees interested in the field of obesity and diabetes (high qualifications recommended for fellowships’ applications). Contact: Dr. Laura Herrero (lherrero@ub.edu)
 
 

TECHNOLOGY TRANSFER (What we offer?)

Mitochondrial bioenergetics (Seahorse) in cultured cells and adipose tissue explants

Tissue, body and cell culture thermogenesis (thermographic camera)

Thermoneutrality mouse chamber

CPT1A flox mice

Adenovirus, lentivirus and AAVs of GFP, CPT1A and CPT1AM 

Fatty acid and glucose oxidation

CPT1 enzymatic activity