We focus our research in the study of the molecular mechanisms involved in behavioral abnormalities and cognitive decline, by using mainly in vivo models of neurodegeneration and cognitive decline (senescence-accelerated mice, SAMP8, Alzheimer’s and Niemann-Pick’s disease mice models). Our expertise is centered in behavioral evaluation and characterization of mice models for senescence and cognitive decline, molecular pathway studies, focus on neuroinflammation, oxidative stress, mitochondrial dynamics and autophagy processes. Our lab has  also available in vitro models (neuronal primary cultures) and C. elegans models of neurodegenerative diseases.