Detall

Conferenciant:  Joel Stavans (Weizmann Institute of Science).

Resum: Circadian clocks in unicellular phototrophic organisms are known to display remarkable reliability. In contrast, not much is known about how circadian clocks perform in a multicellular setting. Are clocks in multicellular cyanobacteria coupled and synchronized with one another through cell-cell communication, or are clocks entrained only by external cues? What is the spatial extent of synchronization? What is the role of cell-cell variations in copy numbers of molecules comprising the KaiABC core clock, demographic noise, in setting the temporal pattern and its robustness? To tackle quantitatively these and other questions, we studied the dynamics of a circadian clock controlled gene in Anabaena sp. PCC 7120, a multicellular cyanobacterium in which cells are arranged one after the other and coupled by protein channels, in a one-dimensional structure.

Link: https://www.ub.edu/portal/web/dp-materia-condensada/inici/-/detall/seminari-fmc-joel-stavans.