University of Barcelona

Genetics and Genomics

Master Thesis/TFM

What is a Master Thesis? The master’s thesis is a piece of original research work written under the direction of an experienced advisor. All students will undertake a Master’s Thesis or Trabajo Final de Master-TFM (30 ECTS). The Thesis is typically based on an experimental research project carried out in one of the research groups of the list shown in this page.Students may be interested in pursuing further research, for instance in a doctoral (PhD) program, or as a researcher in hospitals or research institutes. 

How to do a Master Thesis? You will learn how to plan a research project choose adequate methods to performing the experiments and analysing the results. You will write your Thesis as if it were a scientific publication, critically describing, contemplating and discussing your results in the light of previous scientific literature on the topic.In your written Thesis you are expected to demonstrate that you are capable of scientific thinking, that you are familiar with the methodology and with the topic of your research. The written Thesis is an important exercise for developing skills in project management and written scientific communication. 

Where to find the labs to do the Master Thesis? Below you will find a list of laboratories you can apply. You will see a brief title of the work, a link to the web page of the research group and the name of the supervisor. If you decide to join a particular group for your Master Thesis, write an email to the supervisor and ask for further information and availability. 

If you have problems finding a lab, please contact the master’s coordinator.

 TFM regualtion 

 

Select your laboratory for the research project (Master Thesis/TFM)

Current TFM placements (2021/22)

University of Barcelona, School of Biology

Studying cellular senescence in ageless animals as planarians

Teresa Adell & Emili Saló ; tadellc@ub.edu

 

Evolutionary and Developmental Genomics in insects

Isabel Almudí; ialmudi@ub.edu

 

Molecular mechanisms of subcellular branching: implications for human disease

Sofia J. Araújo; sofiajaraujo@ub.edu

 

How does a mutation in a single gene manage to cause a full intellectual disability- developmental delay syndrome?

Susanna Balcells /Raquel Rabionet; sbalcells@ub.edu / Kelly.rabionet@ub.edu

 

Medical genomics of primary immunodeficiencies

Ferran Casals; ferrancasals@ub.edu

 

Chromatin dynamics and regulation of gene expression during regeneration 

Montserrat Corominas; mcorominas@ub.edu

 

Characterization of iPSC-derived neurons of patients with 7q11.23 rearrangements

Roser Corominas; rosercorominas@ub.edu

 

Gene expression changes in Bex3 KO mice

Jordi García; jordigarcia@ub.edu

 

Comparative genomics of the special amino acid selenocysteine

Marco Mariotti; marco.mariotti.mm@gmail.com 

 

Neural plasticity in the context of stress and cancer 

Marta Morey;  mmorey@ub.edu

 

Function of cbp2 and cbp3 genes in modulating the proliferative response of planarian stem cells during regeneration

Francesc Cebrià i Loli Molina; fcebrias@ub.edu lolimolinaj@ub.edu

 

Dissecting the role of RNA modifying enzymes in stem cell identity

Ana Sevilla; anasevilla@ub.edu

 

Brain Organoid Generation to study Neurodegeneration and Neuroinflammation in Multiple Sclerosis Patients

Ana Sevilla; anasevilla@ub.edu

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Centro Nacional de Análisis Genómico (CNAG)

 

Applying latest generation genomic analysis to the diagnosis of neuromuscular disease patients

Leslie Matalonga, Sergi Beltran; sergi.beltran@cnag.crg.eu; leslie.matalonga@cnag.crg.eu

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Centre for Genomic Regulation (CRG)

 

Towards a training-free GeneID software

Roderic Guigó; roderic.guigo@crg.cat

 

The role of eIF2A in translation regulation in melanoma progression

Fátima Gebauer and Jennifer Jungfleisch; fatima.gebauer@crg.eu jennifer.jungfleisch@crg.eu

 

Transcription factor induced trophectoderm memory in embryonic stem cells.

Thomas Graf and Xiao Wei; thomas.graf@crg.eu xiao.wei@crg.eu

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Bellvitge Biomedical Research Institute; (IDIBELL)

 

Identification of new prognostic and diagnostic markers for urogenital diseases based on ncRNAs in biofluids

Sara Larriba Bartolomé;slarriba@idibell.cat

 

Deciphering the mutational landscape produced by DNA repair defects and their applicability to hereditary cancer

Pilar Mur and Laura Valle; lvalle@idibell.cat pmur@idibell.cat

 

Interpretation of genetic variants in colorectal cancer genes using CRISPR-edited organoids

Laura Valle / Noemi Gonzalez Abuin; lvalle@idibell.cat ngonzaleza@idibell.cat

 

Validation of colorectal cancer gene candidates by means of genetic modification of intestinal organoids by CRISPR-Cas

Mariona Terradas and Laura Valle; lvalle@idibell.cat , mterradas@idibell.cat

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Fundació Puigvert

 

Clinical, genetic and allelic heterogeneity of early-onset hereditary kidney diseases: novel molecular causes of congenital anomalies of the kidney and urinary tract

Elisabet Ars; ears@fundacio-puigvert.es

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Germans Trias i Pujol Research Institute (IGTP), Can Ruti, Badalona

 

Implementation of third generation sequencing of long DNA tandem repeats associated with neurological disorders.

Antoni Matilla-Dueñas; amatilla@igtp.cat

 

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Hospital Sant Joan de Déu - Fundació Sant Joan de Déu

 

Gene editing in vivo: Characterization of a murine model of Congenital Muscular Dystrophy for in vivo assessment of the efficacy and safety of a novel therapeutic strategy for collagen VI-related muscular dystrophies.

Cecilia Jiménez Mallebrera; cecilia.jimenez@sjd.es

 

Investigating the epigenetic changes that drive the initiation of developmental cancers.

Alexandra Avgustinova ; alexandra.avgustinova@sjd.es 

 

Molecular Diagnosis by massive sequencing in mitochondrial disease patients

Delia Yubero, Judith Armstrong; delia.yubero@sjd.es; judith.armstrong@sjd.es

 

Rett Syndrome: Setting the Focus for Therapeutic Targets

Alfonso Oyarzabal; aldeoyarzabal@fsjd.org

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Hospital Clínic de Barcelona

 

Aplicación del test DNA fetal libre para el diagnóstico de la acondroplasia

Irene Madrigal; imadbajo@clinic.cat

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Institute of Biomedical Research (IRB)

 

Modelling cancer in Drosophila: the tissue biology of chromosomal instability.

Marco Milán; marco.milan@irbbarcelona.org

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Institut de Biologia Molecular de Barcelona (IBMB-CSIC-PCB)

 

Development of the Nervous System in Health and Disease

Elisa Martí; emgbmc@ibmb.csic.es

 

Uncovering the Metabolic component of Intellectual Disability: role of the histone demethylase PHF8 maintaining neural progenitor expansion.

Marian Martinez-Balbas; mmbbmc@ibmb.csic.es

 

Transcriptional regulation and cell signaling in Drosophila

Gerardo Jiménez; gjcbmc@ibmb.csic.es

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Institue of Evolutionary Biology (IBE) (CSIC - Universitat Pompeu Fabra)

 

The unknown cell biology and genomics of the most abundant marine microbial eukaryotes

Daniel J. Richter, daniel.richter@ibe.upf-csic.es

 

Celular biology of Corallochytrium limacisporum: role of the cytoskeleton in the cell cycle.

Iñaki Ruiz y Elena Casacuberta; inaki.ruiz@ibe.upf-csic.es

 

Single-cell microbial ecology of the coral holobiont under heat stress

Javier del Campo; jdelcampo@ibe.upf-csic.es

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Institut de Salut Global Barcelona (ISGlobal)

 

Epigenetic regulation of gene expression in malaria parasites

Alfred Cortés; alfred.cortes@isglobal.org

 

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IRBLleida / Universitat de Lleida

 

CRISPR/Cas9 modelling of endometrial carcinoma.

Xavi Dolcet; xavi.dolcet@udl.cat

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Josep Carreras Leukaemia Research Institute (IJC)

 

Engineering human B cells: accelerating the modelling of disease, drug screenings and translation of cancer immunotherapy 

Biola M. Javierre; bmjavierre@carrerasresearch.org

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International (ERASMUS) placements

 

Eukaryotic gene expression

Dep Molecular Biosciences, the Wenner-Gren Institute, Stockholm University

Neus Visa

 

Side-effects to the growing skeleton that occur during radiotherapy

University Karolinska, Stockholm

Phillip Newton

 

Leveraging data from Estonian Biobank (N=200,000) to investigate genetics of female reproductive health and potential personalized strategies

Institute of Genomics, University of Tartu, Tartu, Estonia

Triin Laisk Reedik Mägi

 

Functional plasticity of the spliceosome and the molecular link between pre-mRNA splicing and the maintenance of the transcriptome and genome integrity

Cologne Cluster of Excellence on Cellular stress response in Aging-Associated Disease- CECAD

Mirka Uhlirova

 

Global population genomic structure and demographics of humpback whales

Genetics department, UiT The Arctic University of Norway, Tromsø

Kim Praebel

 

University of Barcelona, School of Biology offers 2022-23

Viral metagenomics for pandemic species surveiilance and characterization

Transcriptomic landscape of planarian, a model organism in regeneration

Josep F. Abril

 

Studying cellular senescence in ageless animals as planarians

Specification of posterior vs anterior identity during planarian regeneration

Teresa Adell i Emili Saló

 

New organs in insects

Isabel Almudí

 

Genetics and cell biology of single-cell branching morphogenesis, implications for human disease

Sofia J. Araújo

 

How does a mutation in a single gene manage to cause a full intellectual disability- developmental delay syndrome?

Susanna Balcells Raquel Rabionet

 

Gene loss, embryo development and CRISPR

Cristian Cañestro & Alfonso Ferrández

 

Genomics and epigenomics of marine embryos in the context of climate change

Cristian Cañestro & Ahmed Elewa

 

Medical genomics of primary immunodeficiencies

Ferran Casals

 

Generation and study of iPSC-derived neurons of patients with 7q11.23 rearrangements

Roser Corominas

 

Expression of transcription factors during epithelial regeneration

Montserrat Corominas

 

Understanding early animal evolution using genome-scale phylogenies

Jesus Lozano

 

Unexpected molecular encounters: How exogenous genes interact with new host genomes when they meet for the first time?

Ignacio Maeso

 

Comparative genomics of the special amino acid selenocysteine

Marco Mariotti

 

Neural plastcity during organ remodeling

Marta Morey

 

Function of CBP/p300 homologues on neoblast cell cylce progression and progenitor specification during planarian regeneration

Loli Molina i Francesc Cebrià

 

What might be the role of VNN2 variants in stroke recovery?

Kelly Rabionet

 

Comparative and evolutionary analysis of multi-gene families in spider genomes

Genomic basis of polygenic adaptation in natural populations

Julio Rozas

 

CRISPR-Cas9 Screening of RNA Modifying enzymes in Pluripotent Stem Cells

Ana Sevilla

 

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University of Barcelona, School of Medicine offers 2022-23

Genetic and epigenetic signatures modulating liver and adipose tissue crosstalk in NAFLD

Pablo M Garcia-Roves

 

Non-genomic Inheritance of environmentally-induced traits: Deciphering epigenetically-driven genetic variation in mammals 

Josep C Jimenez-Chillaron

 

Laboratorio Echevarne

 

Validation of a diagnostic test using NGS in a Molecular Genetic Clinical Laboratory

Raul Santamaria Merino

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Universitat Pompeu Fabra (UPF)

 

Generation of transgenic zebrafish lines to study the spatiotemporal expression of otic neuronal differentiation transcription factors.

Berta Alsina

 

Analysis of the diversity of the human genome: demography and adaptation

David Comas

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Bellvitge Biomedical Research Institute (IDIBELL)

 

Dissecting pathogenic mechanisms in Parkinson's disease through a human iPSC-based disease model

Antonella Consiglio

 

Modeling precancer in germline mismatch repair deficiency to understand early events driving carcinogenesis

Sara Crespo & Marta Pineda

 

Dynamics of stem cell surveillance in live embryos using quantitative imaging

Esteban Hoijman

 

Identification of new prognostic and diagnostic markers for urogenital diseases based on ncRNAs in biofluids

Sara Larriba

 

Analyzing the missing heritability of different hereditary cancer conditions / Deepening the classification of genetic variants in genes related to cancer predisposition

Conxi Lázaro

 

Characterization of mutational processes driving carcinogenesis in syndromes associated with mismatch repair deficiency  

Fatima Marin Nieto & Marta Pineda

 

Organoids for diabetes treatment

Meritxell Rovira

 

Functional characterization of hereditary cancer genes

Laura Valle

 

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Germans Trias i Pujol Research Institute (IGTP), Can Ruti, Badalona

 

 Deciphering the role of HDAC11 in muscular dystrophies

Monica Suelves

 

 Generating Patient Registries and understanding the pathogenesis of Myotonic Dystrophy 1 trough cellular models

Gisela Nogales-Gadea

 

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Hospital Sant Joan de Déu - Fundació Sant Joan de Déu

 

Identifying novel therapeutic vulnerabilities in pediatric cancer

Alexandra Avgustinova

 

Molecular correlation in pediatric patients with drug-resistant focal epilepsy and structural lesion related to mTORpathies

Delia Yubero &  Judith Armstrong

 

Pathophysiology, Genetics and Genomics of Neurogenetic and Developmental Disorders

Francesc Palau

 

Non-genomic Inheritance of environmentally-induced traits: Deciphering epigenetically-driven genetic variation in mammals 

Josep C Jimenez-Chillaron

 

Closing the therapeutic gap for congenital muscular dystrophies: improving efficacy, delivery and safety of CRISPR/cas9 and antisense oligonucleotides based therapies

Arístides López-Márquez

 

Characterisation of a murine model of Congenital Muscular Dystrophy for in vivo assessment of the efficacy and safety of a novel therapeutic strategy for collagen VI-related muscular dystrophies

Cecilia Jiménez Mallebrera

 

Early and predictive serum and CSF biomarkers to optimize therapies for children with spinal muscular atrophy

Selena Trifunov & Cecilia Jiménez

 

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IDIBAPS

 

Gene Regulation in Stem Cells, Cell Plasticity, Differentiation, and Cancer

Antonio Postigo

 

 

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Institut de Biologia Molecular de Barcelona (IBMB-CSIC-PCB)

 

Modeling neurodevelopmental disorders in the mouse and 3D organoids

Maria Lourdes Arbonés

 

Occupancy of histone H1 variants genome-wide and consequences of altering H1 levels on human chromatin organization and gene expression

Albert Jordan

 

The role of the extracellular matrix in the condensation of the nervous system of the Drosophila embryo

Katerina Karkali & Enrique Martín-Blanco

 

Cellular and molecular mechanisms regulating epithelial morphogenesis in Drosophila

Marta Llimargas Casanova

 

The long road of building a nervous system; smooth travels and accidents on the journey to get the Shape, Size, and Cell Diversity

Elisa Martí

 

Understanding epigenetic mechanisms involved in early neurogenesis and neurodevelopmental disorders 

Marian Martinez-Balbas

 

Regeneration versus Tumorogenesis in Drosophila: The transcriptomic response

Mechanisms of control of morphogenetic coordination between different tissues in Drosophila

Enrique Martín-Blanco

 

The Contribution of Human-Acquired Centrosome-Cilia Genes in Normal and Pathological Neural Development

Murielle Saade

 

Role of the basal spliceosome in alternative pre-mRNA splicing

Josep Vilardell

 

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Institue of Evolutionary Biology (IBE) (CSIC - Universitat Pompeu Fabra)

 

Single-cell microbial ecology of the coral holobiont under heat stress

Studying the smallest predator in the ocean using single-cell genomics and long-read metagenomics

Javier del Campo

 

Exploring the genomic basis of terrestrialization across animals through comparative genomics

Rosa Fernández

 

Role and regulation of temporal specifiers during insect development 

Xavier Franch-Marro & David Martín

 

Genomics of adaptation to urban and natural environments in Anopheles and Drosophila

Josefa González

 

The affair of the insect insulin receptors

José Luis Maestro

 

Small RNAs regulating insect oogenesis

M. Dolors Piulachs

 

The unknown cell biology and genomics of the most abundant marine microbial eukaryotes

Daniel J. Richter

 

Unraveling the cell biology of the closest relatives of animals

Iñaki Ruiz Elena Casacuberta 

 

The roots of metazoan regulated cell death pathways

Iñaki Ruiz Michelle Leger 

 

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Institute of Environmental Assessment and Water Research (IDAEA-CSIC)

Identification of biomarkers of exposures to environmental pollutans in zebrafish using a multi-omics approach 

Characterization of epigenetic induced modifications by endocrine disruptors in zebrafish 

Laia Navarro-Martín

 

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Institute of Biomedical Research (IRB)

Drosophila, a model to understand development, regeneration and cancer

Marco Milán

 

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Institut de Salut Global Barcelona (ISGlobal)

 

Regulation of gene expression in malaria parasites

Alfred Cortés

 

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Josep Carreras Leukaemia Research Institute (IJC)

 

Epigenetic and metabolic functions of histone variants

Marcus Buschbeck

 

Characterizing Epigenomic and Epitranscriptomic Alterations in Cancer

Manel Esteller

 

Studying the function of regulatory RNAs in neurodevelopmental diseases

Sonia Guil

 

Epigenetic dysregulation and immune cell crosstalk in inflammation

Esteban Ballestar

 

Impact of the dual catalytic activities of the aging-related sirtuin family members in cancer progression.

Irene Fernández-Duran & Alejandro Vaquero

 

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Institut Hospital del Mar d' Investigació Mèdica(IMIM)

 

Deciphering Intercellular Communication in Cancer and Ageing-related Diseases

Patrick-Simon Welz

 

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Instituto de Biomedicina y Biotecnología de Cantabria (IBBTEC)

 

Dorso-ventral limb patterning and its implication in morphogenesis, evolution and disease

Marian Ros

 

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Centro Andaluz de Biología del Desarrollo

 

Analysis of actomyosin cytoskeleton regulation by cell polarity.

Sol Sotillos Martín

 

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