Today, the CBDD group held a meeting focused on Computational Applications to Structure-Function and Structure-Activity, held at the Food and Nutrition Torribera Campus. We had the pleasure of hosting members of Antonios Kolocouris’ group from the National and Kapodistrian University of Athens, who joined us for a full day of stimulating presentations and scientific exchange. […]

Our latest preprint is now available on ChemRxiv! In this study, we investigate how hydrogen bonds contribute to the stability of molecular glue (MG)-induced ternary complexes. Our findings show that the strengthening of polar interactions is a consistent physicochemical mechanism that supports the action of chemically diverse MGs. Based on these insights, we propose a […]