Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects. This is stated in a study led by the research group of the Diabetes and Associated Metabolic Diseases Networking Biomedical Research Centre (CIBERDEM) of the University of Barcelona (UB) and the Sant Joan de Déu Research Institute (IRSJD), which included the participation of a team of the Alberto Sols Biomedical Research Institute (CSIC/UAM).

More