On Monday 25th of October, Miriam has successfully defended her PhD thesis entitled Biophysical and structural approaches to discover small-molecule modulators of challenging targets in cancer. During her thesis she has employed a wide range of structural and biophysical methodologies to uncover ligandability of the E3 ligases family, including the discovery of the first FBXW7 […]

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A junior postdoc position has opened in our lab, funded by La Fundació La Marató de TV3. The project involves the discovery of druggable binding sites using mixed-solvent molecular dynamics, hit identification by means of virtual screening, and the development of confirmed hits into effective PROTAC molecules. Potentially, the candidate will also perform experimental testing […]

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A PhD positions is available in our lab in the context of a Marie Curie Innovative Training Network (ALLODD). Applications from MSc students finishing their Bioinformatics (or related) are particularly welcome. The ALLODD project is a collaboration between 13 academic and industrial organizations with 14 PhD students in total. The aim of ALLODD is to […]

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Serena has successfully defended her PhD thesis entitled ‘Molecular recognition and chemical space navigation in drug discovery’. In her thesis she has developed a very successful fragment evolution platform and applied it to discover new BRD4 ligand scaffold. She also investigated the very interesting case of the hydrophobic waters hotspot, and the implication of this […]

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Carles Curutchet, full professor of the IQTC, and Xavier Barril, ICREA research professor of the IBUB, have been awarded an EU Marie Curie Innovative Training Network. The ALLOD ITN (Allostery in Drug Discovery), coordinated by Prof. Zoe Curnia, from the Biomedical Research Foundation, Academy of Athens (Greece), involves a number of academic partners and pharmaceutical companies, and aims to train a […]

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Salvatore successfully defended his PhD thesis entitled “Biophysical Techniques for the Investigation of Protein-Ligand Complexes”. In his work he applied different biophysical techniques to different projects with huge relevance in the drug discovery field. All the hard work was truly reflected and both the defence and the results were brilliant. You have a bright future […]

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Dr. Sergi Ruiz has won the Ramon Margalef 2020 award for his paper «Dynamic undocking and the quasi-bound state as tools for drug discovery», published at  Nature Chemistry. This award is given to the most exceptional scientific work derived from a PhD in the University. Regarding Dynamic Undocking, Sergi remarkes this method to design drugs […]

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Moira successfully defended her thesis entitled “Fragment-to-Lead Optimization with Automated and Iterative Virtual Screening”. Her Fragment Evolution Automated platform (FrEvolAtion) has shown to be a powerful tool for Fragment-based Drug Discovery and her results finding binders for the NUDT1, BRD4, HSP90 and other kinases thoroughly validate the reach of the methodology. We hope you have […]

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