Design, synthesis and evaluation of novel soluble epoxide hydrolase (sEH) inhibitors for inflammatory diseases.
This is a more recent topic within our group. We have recently discovered that the lipophilic cavity of the sEH…
This is a more recent topic within our group. We have recently discovered that the lipophilic cavity of the sEH…
Within this project we designed, synthesized and evaluated novel polycyclic compounds as analogs of the clinically approved NMDA receptor antagonists…
Amantadine and rimantadine have been in clinical use as anti-influenza A virus agents for decades. The mechanism of action of…
In the field of cancer therapeutics, we are working in three multidisciplinary projects in collaboration with excellent professionals. Increasing the…
Human African Trypanosomiasis (HAT), caused by Trypanosoma brucei gambiense or T. brucei rhodesiense, and malaria, caused by Plasmodium species, are…
This project is the result of a collaboration with the group of Dr. Carles Galdeano. c-Myc degradation with PROTAC molecules…